Charting Kidney Cancer Metabolism Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.Insights into the Function of the Main Class of Drug Targets About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.Visualizing a Cancer Drug Target at Atomic Resolution Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.Honey’s Potential to Save Lives The healing powers of honey have been known for thousands of years. 3-D Printed Lifelike Liver Tissue for Drug Screening A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling. Cytoskeleton Crew Findings confirm sugar's role in helping cancers survive by changing cellular architecture.Biomarker for Recurring HPV-Linked Oropharyngeal Cancers A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University. Valvena, GSK Sign New R&D Collaboration Valneva to supply process development services for EB66® -based Influenza vaccines. Light Signals from Living Cells Fluorescent protein markers delivered under high pressure.Cellular 'Relief Valve' A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
Managing Pharmaceutical Lab Data Management to Ensure Compliance Join Stacey Brown and William Leonard, Senior Validation Analysts for Informatics at Thermo Fisher Scientific, to understand more about the complex requirements of pharmaceutical data management.
Translation of Omic Data into Personalised Oncology Tools The Challenge and the Reward William Gallagher, University College Dublin, speaking at Diagnostics & Biomarkers 2015.
Development of a Packed Bed Reactor for the Synthesis of Peptides and Foldamers: A Revolutionary Reduction of the Amino Acid Excess Istvan Mandity, University of Szeged, speaking at Discovery Chemistry Congress 2015.
Plasma Vitronectin Predicts Response to Fluoropyrimidine-oxaliplatin (FOLFOX) Chemotherapy in Metastatic Colorectal Cancer Sarah Hayes, University of Sydney, speaking at Diagnostics & Biomarkers 2015.
SPR Imaging-based Microarray for Enhanced Multianalyte Detection in Blood Plasma Marketa Bockova, Institute of Photonics and Electronics ASCR, speaking at Biodetection & Biosensors 2015
Microwave-to-Terahertz Sensing in Microfluidic Systems Norbert Klein, Imperial College London, speaking at Lab-on-a-Chip & Microfluidics 2015
Parallel Tracking i-biomarkerT Development with Drug Development for Maximum Benefit Kevin Cox, Imanova Limited, speaking at Diagnostics & Biomarkers.
The First Discovery of a Single Digit Nanomolar Small Molecule Blocker of a Protein-protein Interaction Target Nils Hansen, Vipergen ApS, speaking at Discovery Chemistry Congress 2015.
Machine Learning and Image Analysis Methods in High-content Screening for Phenotypic Drug and Gene Discovery Peter Horvath, Hungarian Academia of Sciences, speaking at Screening Europe 2015
Development of a Point-of-Care Diagnostic for Influenza Detection with Antiviral Treatment Effectiveness Indication Richard Murdock, USAF, speaking at Point of Care Diagnostics 2015