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Scientific News
Two Studies Identify A Detectable, Pre-Cancerous State In The Blood
Findings pave way for new lines of cancer research focused on detection and prevention.
Antibiotic Resistance Threatens Future of Modern Medicine
Overuse and misuse of antibiotics, one of the key contributors to antimicrobial resistance (AMR).
Powerful Method To Speed Cancer Drug Discovery Unveiled
The new method lets researchers identify weak and previously undetectable interactions between proteins inside living cells.
Translating Research: New Drugs from Fish Oil Could Aid Artery Repair
Every year, more than a half-million Americans undergo procedures to have a narrowed coronary artery propped open with a small metal mesh tube, or stent.
Direct Drug Screening Of Biopsies Could Overcome Resistance
Combining genetic with pharmacologic screening of tumors may enable truly individualized treatment regimens.
Almac Announces Launch of CLIA Validated Next Generation Sequencing Assay
P53 considered important biomarker for cancer drug discovery.
Next-Gen Melanoma Drug Excels in Lab Tests
Anti-cancer activity was reported in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733.
Blood Test Could Reduce Antibiotic Use
A new blood biomarker test that indicates whether bacteria is the cause of a patient’s lung infection is now being studied at UPMC Presbyterian.
New Targets and Test to Develop Treatments for Memory Disorders
The study focuses on kinesin, a molecular motor protein that plays a role in the transport of other proteins throughout a cell.
Drugging the Undruggable
Discovery opens up possibility of slowing cancer spread.

High Content Screening for Inhibitors of Protein Interactions and Post-translational Modifications in Primary Cells by Proximity Ligation
Karl-Johan Leuchowius, PhD Student, Uppsala University, speaking at Screening Europe 2010

Discovery and Development of Novel USP7 Inhibitors
Craig Leach, Associate Director, Progenra, Inc, speaking at Screening Europe 2010

Interaction of G-Protein-Coupled Receptors With Arrestins
Cornelius Krasel, Lecturer in Pharmacology, University of Reading, speaking at Screening Europe 2010

Virtual Fragment Screening by Glide
György Keseru, Head of Discovery Chemistry, Gedeon Richter, speaking at Screening Europe 2010

sciWIFTER is new Paradigm for in vitro Cellular Screening
Igor Ivanov, Managing Director, Oncolead, speaking at Screening Europe 2010

Kinetic Cell-based Morphological Screening: Detection of Pro-Arrhythmic Compounds, Mechanism of Compound Action and Off-Target Effects
Jeff Irelan, Research Scientist, ACEA Biosciences, speaking at Screening Europe 2010

Small Molecule Inhibition of Eicosanoids May Prove a Viable Approach for Treatment of Platelet-Mediated Thrombosis.
Michael Holinstat, Assistant Professor, Thomas Jefferson University, speaking at Screening Europe 2010

ADP-Glo: A Universal Bioluminescent and Homogenous ADP Monitoring Assay for Detection of Enzymatic Activities of Kinases and Phosphatases
Said Goueli, Research Fellow, Promega, speaking at Screening Europe 2010

Biomarkers of Metabolic Syndrome in Clinical Trials
This will discuss the latest developments in biomarkers for metabolic syndrome. The topics will include: 1) Pre-analytical and analytical concerns regarding gut and incretin hormones, 2) dysfunctional HDL biomarkers in metabolic syndrome, and 3) kidney injury markers and their usefulness in diabetic nephropathy.

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