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Charting Kidney Cancer Metabolism
Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Honey’s Potential to Save Lives
The healing powers of honey have been known for thousands of years.
3-D Printed Lifelike Liver Tissue for Drug Screening
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling.
Cytoskeleton Crew
Findings confirm sugar's role in helping cancers survive by changing cellular architecture.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Valvena, GSK Sign New R&D Collaboration
Valneva to supply process development services for EB66® -based Influenza vaccines.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.

Functional Interrogation of 'omics' Data
Dr Kartiki V Desai, National Insitute of Biomedical Genomics, speaking at Screening Asia 2011.

Understanding Fat Metabolism at the Organism Level – A Comprehensive Metabolic Screen of C. elegans.
Dr Jules Griffin, University of Cambridge, speaking at Advances in Metabolic Profiling 2011.

Actionable Biomarkers for Rheumatoid Arthritis
Dr William Robinson, Stanford University, speaking at Microarray World Congress 2011.

The Potassium Channels Kv1.3 and KCa3.1 as Targets for Inflammatory Brain Pathologies
Professor Heike Wulff, University of California, speaking at Ion Channel Targets 2011.

Alpha2* Nicotinic Acetylcholine Receptors as a Therapeutic Target for Memory Enhancement
Dr Katumi Sumikawa, University of California, speaking at Ion Channel Targets 2011.

Smooth Muscle Kv7 (KCNQ) Potassium Channels: Important New Therapeutic Targets
Professor Kenneth Byron, Loyola University Chigaco, speaking at Ion Channel Targets 2011.

Protons, Heat and Mechanical Force Converge to Gate Two-Pore Potassium Channels at the Selectivity Filter
Dr Slav Bagriantsev, University of California, speaking at Ion Channel Targets 2011.

Background and Key Drivers Leading to Clinical Immunogenicity
Dr Matthew Baker, Chief Scientific Officer at Antitope Ltd, speaking at Bioprocessing, Biologics and Biotherapeutics 2011.

The Potential of High Content Imaging in Primary Screening
Daniela Siebert, Novartis, speaking at Screening Europe 2011

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