Charting Kidney Cancer Metabolism Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.Insights into the Function of the Main Class of Drug Targets About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.Visualizing a Cancer Drug Target at Atomic Resolution Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.Honey’s Potential to Save Lives The healing powers of honey have been known for thousands of years. 3-D Printed Lifelike Liver Tissue for Drug Screening A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling. Cytoskeleton Crew Findings confirm sugar's role in helping cancers survive by changing cellular architecture.Biomarker for Recurring HPV-Linked Oropharyngeal Cancers A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University. Valvena, GSK Sign New R&D Collaboration Valneva to supply process development services for EB66® -based Influenza vaccines. Light Signals from Living Cells Fluorescent protein markers delivered under high pressure.Cellular 'Relief Valve' A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
Modeling and Prediction of Antibody Chromatography Purification Professor Christian Frech, Mannheim University of Applied Science, speaking at BioProcessing, Biologics and Biotherapeutics Congress.
A Systematic Investigation of Candidate Breast Cancer Progression-Associated Biomarkers Identified from Omic Screens: Leveraging Antibody-Based Proteomics Prof. William Gallagher, Chief Scientific Officer at OncoMark, speaking at Advances in Microarray Technology 2011.
A High Quality High Content Screening Assay for Intracellular Leishmania Manu De Rycker, University of Dundee, speaking at Screening Europe 2011
High Content Screening for Cytoskeletal Rearrangements María Montoya, Centro Nacional de Investigaciones Cardiovasculares, speaking at Screening Europe 2011
Kinetic Monitoring of Cellular cAMP/cGMP Signalling Reinhard Seifert, Sibion Biosciences, speaking at Screening Europe 2011
From Acquisition to Analysis: Tools to Improve the High Content Screening Workflow for Stem Cell Assays Ben Haworth, Molecular Devices, speaking at Screening Europe 2011.
Development of an Ultra-high Throughput Long Non-coding RNA Screening System Jan Hellemans, speaking at Advances in qPCR 2011
Latent Hit Identification in Primary Screening Data with Compound Set Enrichment Thibault Varin, PostDoctoral Fellow, Novartis, Speaking at Medchem Europe 2011.
State-of-the-Art in Ligand-Based Virtual Screening Jürgen Bajorath, Professor, Department of Life Science Informatics, University of Bonn, speaking at Medchem Europe 2011.