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New Tool Uses 'Drug Spillover' to Match Cancer Patients with Treatments
Researchers have developed a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker (KAR) predicts what genetics are truly driving the cancer in any population of cells and chooses the best "kinase inhibitor" to silence these dangerous genetic causes of disease.
HIV Susceptibility Linked to Little-Understood Immune Cell Class
High levels of diversity among immune cells called natural killer cells may strongly predispose people to infection by HIV, and may be driven by prior viral exposures, according to a new study.
Sweet Revenge Against Superbugs
A special type of synthetic sugar could be the latest weapon in the fight against superbugs.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
Tracking Breast Cancer Before it Grows
A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes.
Zebrafish Reveal Drugs that may Improve Bone Marrow Transplant
Compounds boost stem cell engraftment; could allow more matches for patients with cancer and blood diseases.
DNA Damage Seen in Patients Undergoing CT Scanning
Along with the burgeoning use of advanced medical imaging tests over the past decade have come rising public health concerns about possible links between low-dose radiation and cancer.
The Light of Fireflies for Medical Diagnostics
EPFL scientists have exploited the light of fireflies in a new method that detects biological molecules without the need for complex devices and high costs.
Vital Protein in Healthy Fertilization Process Identified
Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice.

Modifying Cell Lines for Target Discovery and Validation
In this 30-minute seminar, we will discuss the process of genome editing, address factors affecting the design of a genome editing project, and explore the application of modified cell lines for target discovery and validation.

Strategies for the Identification of Lead Molecules to Sustain a Discovery Organisation
Steve Rees, AstraZeneca, speaking at Drug Discovery and Development 2014

Machine Learning for Building Models of Cell Perturbation
Robert Murphy, Carnegie Mellon University, speaking at Drug Discovery and Development 2014

Kinases as Targets for Drug Discovery in an Academic Setting
William Janzen,The University of North Carolina at Chapel Hill, speaking at Drug Discovery and Development 2014

Balancing Leverage with Stewardship of a Corporate Compound Collection
Rose Gonzales, Pfizer Global R&D, speaking at Drug Discovery and Development 2014

Heterogeneity of Cellular Responses to Perturbagens in Drug Discovery and Development
Lansing Taylor, University of Pittsburgh, speaking at Drug Discovery and Development 2014

Repurposing Approaches for Rare and Neglected Tropical Diseases
John Mckew, National Institutes of Health, speaking at Drug Discovery and Development 2014

Pivot Park Screening Centre, The Pivot for Screening Knowledge and Expertise
Helma Rutjes, Pivot Park Screening Centre, speaking at Drug Discovery and Development 2014

What Can We Learn from Fragment Based Optimization Programs?
Gyorgy Keseru, Hungarian Academy of Sciences, speaking at Drug Discovery and Development 2014

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