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Promising Class of New Cancer Drugs Cause Memory Loss in Mice
New findings from The Rockefeller University suggest that the original version of BET inhibitors causes molecular changes in mouse neurons, and can lead to memory loss in mice that receive it.
Electrical Control of Cancer Cells
Research led by scientists at The University of Texas Health Science Center at Houston (UTHealth) has revealed a new electrical mechanism that can control these switches.
Signature of Microbiomes Linked to Schizophrenia
Studying microbiomes in throat may help identify causes and treatments of brain disorder.
Inflammation Linked to Colon Cancer Metastasis
A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
Determining the Age of Fingerprints
Watch the imprint of a tire track in soft mud, and it will slowly blur, the ridges of the pattern gradually flowing into the valleys. Researchers have tested the theory that a similar effect could be used to give forensic scientists a way to date fingerprints.
Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies
CHOP genomics expert leads analysis of genetic architecture, with eye on repurposing existing drugs.
Surprising Mechanism Behind Antibiotic-Resistant Bacteria Uncovered
Now, scientists at TSRI have discovered that the important human pathogen Staphylococcus aureus, develops resistance to this drug by “switching on” a previously uncharacterized set of genes.
Tissue Bank Pays Dividends for Brain Cancer Research
Checking what’s in the bank – the Brisbane Breast Bank, that is – has paid dividends for UQ cancer researchers.
Researchers Publish Landmark “Basket Study”
Researchers from Memorial Sloan Kettering Cancer Center (MSK) have announced results from the first published basket study, a new form of clinical trial design that explores responses to drugs based on the specific mutations in patients’ tumors rather than where their cancer originated.

Screening for Chemical Tools: Considerations on Compound Screening Collections, Assay Development and High-throughput Screening
Dominique Audenaert, VIB - Ghent University, speaking at European Lab Automation 2012

Multi-analyte Procedures for Target Screening and Quantification of Drugs in Blood using LC-MS/MS: Possibilities and Limitations
Hans Maurer, Saarland University, speaking at European Lab Automation 2012.

Sample Management and HTS: Convergent Platforms and Universal Solutions to Simplify the Integration Challenge
Chris Walsh, Brooks Life Science Systems, speaking at European Lab Automation 2012

Dynamic Cell Culture for Drug Discovery: Stretching Mechanotransduction from the Lung to the Lab
Dr. Sanjit Nirmalanandhan, University of Kansas Medical Center, speaking at Cell Culture 2012.

ESPRIT: High Throughput Screening for Soluble Expression Constructs of Difficult-to-express Proteins
Darren Hart, European Molecular Biology Laboratory, speaking at European Lab Automation 2012

Fragment Based de novo Ligand Design: A Valuable Optimisation Tool in Fragment Based Lead Discovery
Peter Johnson, University of Leeds, speaking at Discovery Chemistry Congress 2012.

Fragment-Based Drug Discovery - Getting in Shape
Doris Hafenbradl, Biofocus, speaking at Discovery Chemistry Congress 2012.

The Versatility of Fragment Screening Approaches and the Application of Fragment Binding Information in Durg Discovery
Stefan Geschwindner, AstraZeneca, speaking at Discovery Chemistry Congress 2012.

Challenges of an Open Access Screening Platform in Academia
Edgar Specker, Leibniz Institute of Molecular Pharmacology, speaking at European Lab Automation 2012

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