Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Join | Sign in
Videos
What is LabTube?...
SELECTBIO Corporate Video...Life of a Scientific Poster...IntelliQube® Fully Automated PCR Setup, ...

Featured Products
Featured Product - Miriad RVF Antibody Detection Kit
Miriad RVF Antibody Detection Kit
Featured Product - IMMULITE 2000 XPi Immunoassay System
IMMULITE 2000 XPi Immunoassay System

Webcasts
Webcast - Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!Accelerate Your Research With Tecan´s New Multimode Microplate Reader Platform!
In this webinar, solutions will be presented for fast DNA quantification, single cell counting and viability analysis, and automating long-term live kinetic cell assays.
Advanced Molecular Tools for Proteome Analyses
Masood Kamali-Moghaddam, Uppsala University, speaking at Advances ibn qPCR and dPCR 2014

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Chromatography Resin Market by Application, Techniques & Type - Trends & Forecast to 2018
MarketsandMarkets

The chromatography resin market is expected to grow at a decent pace during the coming decade driven by its increasing application in monoclonal antibody production and food analytics.
Cell Analysis Market by Instruments, Consumables & Application - Global Forecast to 2018
MarketsandMarkets

The global cell analysis market is a technology-driven market and is marked by the ?Threat of Obsolescence,? wherein technologies as well as their adoption by end users changes very rapidly. Hospitals, academic and government institutes, as well as pharmaceutical and biotechnology companies are increasing their focus on using cell analysis as a powerful research tool in research, drug discovery, and diagnosis.
Security Technologies in Biotechnology
RI Technologies

The report serves as a guide to security technology industry for biotechnology applications, covering more than 350 companies that are engaged in security technology/products and services.
Blood - Components, Testing & Collection
RI Technologies

This market insight report gives an insight into global blood ? components, testing and collection market. The report also provides market analytics by Product Type.
Multi-Mode Microplate Reader Trends 2013
HTStec

This market report summarizes the results of HTStec’s 4th industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2013.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
Monoclonal Antibodies Market in Rheumatoid Arthritis to 2018
GBI Research

The currently marketed monoclonal antibodies are highly successful products in the rheumatoid arthritis market, constituting four of the global top 20 best-selling drugs. Significant market exclusivity, expiries in the forecast period and yet more monoclonal antibodies in development will change the dynamics in and this highly lucrative market in the forecast period until 2018.
Life Science Consumables 2013: Markets and Opportunities
Biopharm Reports

Techniques such as PCR, DNA microarray, DNA sequencing, mass spectrometry and flow cytometry have grown significantly in the last decade and by 2015 markets for these five areas are expected to exceed $50 billion, globally. In these and related fields, consumables are generally the second or third largest area in cost terms, after instrumentation.
Scientific News
Strengthening the Immune System’s Fight Against Brain Cancer
NIH-funded research suggests novel way to improve vaccine efficacy in brain tumors.
Surprising Finding In Stroke Research
Scientists at The University of Manchester have made an important new discovery about the brain’s immune system that could lead to potential new treatments for stroke and other related conditions.
Macrophages May Play Critical Role in Melanoma Resistance to BRAF Inhibitors
Discovery could lead to a new melanoma target.
Autoimmune Disease Super-Regulators Uncovered
Scientists discovered key genetic switches, called super-enhancers, involved in regulating the human immune system.
Gene Discovery Provides Clues To How TB May Evade The Immune System
The largest genetic study of TB susceptibility to date has led to a potentially important new insight into how the pathogen manages to evade the immune system.
Tetanus Shot Improves Patient Survival With Brain Tumor Immunotherapy
Study shows patient survival increased when the immune system was primed with a tetanus booster.
First Look At Hospitalized Ebola Survivors' Immune Cells Could Guide Vaccine Design
Emory and CDC researchers have been examining immune cells obtained from four patients treated at Emory University Hospital in 2014.
Energetic Immune Cells are Vital for Fighting Disease
Removing HuR prevented the proper growth and function of B cells.
Adults Only Really Catch Flu About Twice a Decade, Suggests Study
Researchers developed a mathematical model of how our immunity to flu changes over a lifetime as we encounter different strains of the virus.
NIH Announces $41.5 Million in Funding for the Human Placenta Project
Better understanding of the placenta promises to improve the health of mothers and children.
Business News
Compugen Announces Planned Relocation of Headquarters to Larger Facilities
New facilities double available space for corporate offices and research and discovery in Israel.
Celldex Announces Clinical Trial Collaboration with Roche
Collaboration to evaluate the combination of varlilumab and MPDL3280A.
WuXi PharmaTech to Build New Cell Therapy Manufacturing Facility
Facility is designed for CAR T cells and other cancer immunotherapies.
Key TxCell Patent to be Granted in the US for its Lead Product Ovasave®
Patent ensures protection for Ovasave® in the US until 2030 minimum.
First Treatment Approved Under EAMS
New immunotherapy (pembrolizumab) made available in the UK for treatment of adults with advanced melanoma.
BioLineRx’s Treatment for Type 1 Diabetes Effective in Preclinical Trials
Results of experiments with BL-9020, a new antibody treatment, published in PLoS One.
First Treatment Approved under EAMS Developed Using Antibody Humanization Expertise at UK’s MRC Technology
New breakthrough immunotherapy (pembrolizumab) launched in the UK for treatment of adults with advanced melanoma.
Adaptimmune Appoints Lawrence M. Alleva to its Board of Directors
Lawrence M. Alleva will join the Board as an independent, non-executive director.
Compugen Expands and Strengthens Business Development Team
Felix Karim, PhD, joins Company as Vice President Corporate & Business Development.
ModiQuest Research and Cellectis to Collaborate
Collaboration on antibody generation for potential CAR development.

Events
Asthma & COPD
13 Apr 2015
Asthma & COPD ...
2nd Microbiome Forum: Europe
07 May 2015
2nd Microbiome Forum: Europe ...
EMBL Conference on the Human M
10 May 2015
EMBL Conference on the Human M ...
EMBL CONFERENCE: BioMalPar XI:
11 May 2015
EMBL CONFERENCE: BioMalPar XI: ...

ePosters
Novel culture medium using a small-molecule agonist of thrombopoetin receptor
1ReproCELL, Inc. & 2Nissan Chemical Industries

ReproHSC medium for the culture of hematopoietic stem cells. facilitates the culture and expansion of CD34+/CD38- cells that retain their HSC properties
Flexible automated platform for blood group genotyping on DNA microarrays
1 Établissement Français du Sang Rhône-Alpes, Lyon, France. 2 Établissement Français du Sang, La Plaine Saint Denis, France. 3 Établissement Français du Sang Alpes-Méd

The purpose of this project was to set up and validate a flexible robotic platform using 96-well DNA microarray for multiplex blood group genotyping.
Non-invasive Liquid Biopsy
1 Life Technologies AS, Ullerchausséen 52, 0379, Oslo, Norway; 2Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; 3 Centre for Cancer Biomedicine, Univ

Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.
THE MASTOCYTOSIS SOCIETY SURVEY ON MAST CELL DISORDERS: Part 2-Clinical Experiences, Co-Morbidities, Diet, Families and Opinions
The Mastocytosis Society, Inc., USA; Mastocytosis Center, Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, U

Mast cell diseases such as mastocytosis and mast cell activation syndromes involve abnormal proliferation or activation of these cells leading to many potentially debilitating symptoms. In order to determine the characteristics and experiences of people known or suspected to have a mast cell disorder, The Mastocytosis Society (TMS), a U.S. based patient advocacy, research and education organization, conducted a survey of patients.
Safety Of A Sublingual Tablet of House Dust Mite Allergen Extracts In An Environmental Exposure Chamber Study
Stallergenes, Antony, France

In an environmental exposure chamber (EEC) study, treatment with HDM sublingual tablets in patients with HDM-associated allergic rhinitis was generally well tolerated regardless of dose. While asthma and related symptoms were more common during the peri-EEC challenge periods, rates did not differ between active and placebo treatment.
Safety Of The 300 IR and 500 IR Doses Of A House Dust Mite Allergen Extracts Sublingual Tablet In Adults with Allergic Rhinitis
Stallergenes, Antony, France

In a randomized, DBPC study in patients with HDM-associated allergic rhinitis, treatment with HDM sublingual tablets at doses of 300IR and 500IR was associated with a favorable safety profile. There was no appreciable difference in tolerability between the tested doses.
Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge TheatreTM


Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge Theatre
Field Performance of a New Technology with the Potential to Identify Allergy and Asthma Triggers
Inspirotec LLC, Glenview, IL, Argonne National Laboratory, Lemont, IL, Department of Ecology and Evolution, University of Chicago, Chicago, IL

This work introduces a very simple plug-and-play device that can sample air at a high volume flow rate with no moving parts. Aerosol particles are captured on electrodes and eluted for testing. We show that performance of the device is substantially equivalent to capture by pumping through a filter for immunological and molecular analysis.
Marked increase in basophil activation during non-anaphylactic allergic reactions to peanut in man
Imperial College London

Our data imply an important role for basophils in the evolution of acute IgE-mediated reactions to food allergens.
Ten-Year Experience with Sublingual Immunotherapy for Juniper Pollenosis
Allergy and Asthma Specialists

Efficacy of sublingual immunotherapy for Juniper induced allergic rhinitis is presented.
Application Notes
Characterization of IgG Monomers & Their Aggregates
Malvern Instruments Limited

In this application note we characterize two antibody samples using column calibration and multi-detection SEC.
Understanding Antibody and Viral Glycoprotein Interactions Using CG-MALS
Wyatt Technology Corporation

We used size-exclusion chromatography coupled with multi-angle light scattering to determine the molar mass and native oligo-meric state of a viral glycoprotein.
Charge and Interaction Analysis for Predicting Antibody Formulation Stability
Wyatt Technology Corporation

Colloidal stability is a key solution property of a biotherapeutic formulations, indicative of long-term stability. As it is readily measured over much shorter time scales than long-term stability testing or even accelerated testing regimens, measurements of colloidal stability are often utilized in the course of formulation work to screen out poorly behaved conditions.
Performing ADCC Reporter Bioassay with an Environmentally Controlled Microplate Reader
Tecan Group Ltd.

The Promega ADCC Reporter Bioassay provides effector and target cells in frozen, thaw-and-use format, removing the need for isolating or culturing cells in order to perform the assay. Reporter induction requires a six-hour to overnight incubation in a standard cell culture incubator. The CO2 and temperature control features of the Tecan Infinite® 200 PRO with GCM allow the assay induction to be performed without the requirement for a cell culture incubator.
Tag-lite® two-cell assay: a valuable tool for protein drug discovery
Tecan Group Ltd.

Antibodies are central mediators of the immune system, IgG being the most dominant. Binding of IgG/antigen complexes to membrane-bound Fc? receptors triggers a cellular immune response. Alterations in the Fc portion of the antibody by introducing mutations can lead to complete abolition of Fc? receptor binding. This describes the development of a cellbased TR-FRET assay to determine the simultaneous binding of an antibody to its antigen and huFc?RIIIa present on different cells.
Transcreener® ADP2 TR-FRET Red Assay
Tecan Group Ltd.

Adenosine diphosphate (ADP) is an important mediator of cellular metabolism that is essential for maintaining energy levels. The Transcreener ADP2 TR-FRET Red Assay is intended for the detection of ADP production by any kinase or ATPase, and has been developed specifically for high throughput screening applications.
Efficient washing of magnetic beads
Tecan Group Ltd.

The use of magnetic beads as the solid phase in a multiplexed ELISA enables high throughput cytokine screening and offers several advantages over common ELISA assays with direct coupling of the analyte to the well-surface.
Automating ELISAs on Tecan’s Freedom EVO® using Optimiser™ technology from Siloam Biosciences
Tecan Group Ltd.

One of the challenges in life sciences research today is to discover methods for running key assays more quickly, more reliably and using lower volumes of reagents and sample, but still with improved sensitivity. One area where this particularly holds true is for traditional enzyme-linked immunosorbent assays (ELISAs), whose application provides a useful measurement of antigens, including cytokines and a host of other biomarkers.
Validating the Expression Consistency of a Housekeeping Protein
Bio-Rad Laboratories

Housekeeping proteins (HKP) are typically used as loading controls because it is assumed that the HKP expression level remains consistent across samples. However, there is evidence that HKP expression levels change in many scenarios, including siRNA treatment, cell death, cell differentiation, etc.
A Method for Greater Reliability in Western Blot Loading Controls: Stain-Free Total Protein Quantitation
Bio-Rad Laboratories

Reliable assessment of changes in target protein levels by western blot requires measurement of both the target and loading control proteins in the linear dynamic range. Stain-free technology is a novel method introduced by Bio-Rad to visualize and quantify proteins in gels and blots.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters