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  Events - February 2014

3rd International Symposium on Higher Order Structure of Protein Therapeutics (HOS 2014)

18 Feb 2014 - 20 Feb 2014 - Arlington, VA, USA

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This conference is about Biophysical properties such as protein conformation, protein dynamics, self-association, aggregation and particulate formation contribute either individually or collectively to the quality attributes of protein therapeutics. There is thrust from the FDA to characterize the biophysical properties of protein therapeutics so as to assess how protein structure is affected by manufacturing, storage and delivery; thereby evaluating its impact on clinical safety and efficacy. A noticeable lack of understanding of existing biophysical characterization methods used in monitoring the quality attributes of protein therapeutics such as conformation and higher order structure has created hurdles in the application of these technologies for evaluating drug safety.  Use of the appropriate biophysical method, method development and qualification to characterize the quality attributes at different stages of the product lifecycle are therefore a matter of interest and debate. This Symposium will focus on various biophysical characterization methods, theory and practice of biophysics, technical data from academia and industry as well as method qualification, validation and setting specifications.

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