Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Become a Member | Sign in
Home>Events>This Event
  Events - October 2013


To SEC-MALS & Beyond - The Road to Biotherapeutic Development Illuminated by Light Scattering

01 Oct 2013 - 01 Oct 2013 - Online Webinar



Bookmark and Share


We present HPLC/SEC-MALS, the technique for quantifying absolute molecular weight, size, polydispersity, aggregation and degree of conjugation. Developers of biopharmaceuticals rely on Wyatt Technology's SEC-MALS products to navigate the path to drug product with confidence.  We review how the Wyatt light scattering instruments constitute a unique set of orthogonal and complementary methods alongside SEC-MALS: SEC-DLS for size & conformation; FFF-MALS for separation & characterization; CG-MALS for intermolecular interactions, and microwell plate-based DLS for high-throughput screening.

Who should attend:
• Researchers assessing biomolecular quality, including size and concentration of aggregates, degree of polymer conjugation, and column interactions
• Protein chemists optimizing production, modification, and formulation of biotherapeutic lead molecules
• Laboratory Managers/Directors/Supervisors performing biophysical characterization

Questions to be answered:
• How do MALS and DLS increase the chromatography data value for advanced analysis of IgG, ADCs, PEGylated proteins, and new format biotherapeutics?
• How can batch light scattering contribute to assessing stability and developing robust formulations?



Further information
Scientific News
Sorting Through Cellular Statistics
Aaron Dinner, professor in chemistry, and his graduate student Herman Gudjonson are trying to read the manual of life, DNA, as part of the Dinner group’s research into bioinformatics—the application of statistics to biological research.
Women’s Immune System Genes Operate Differently from Men’s
A new technology reveals that immune system genes switch on and off differently in women and men, and the source of that variation is not primarily in the DNA.
Experimental MERS Vaccine Shows Promise in Animal Studies
A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques, report National Institutes of Health scientists who designed the vaccines.
HIV Susceptibility Linked to Little-Understood Immune Cell Class
High levels of diversity among immune cells called natural killer cells may strongly predispose people to infection by HIV, and may be driven by prior viral exposures, according to a new study.
New Weapon in the Fight Against Blood Cancer
This strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
Scientists Create CRISPR/Cas9 Knock-In Mutations in Human T Cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9.
Researchers Develop Vaccine that Protects Primates Against Ebola
A collaborative team from The University of Texas Medical Branch at Galveston and the National Institutes of Health have developed an inhalable vaccine that protects primates against Ebola.
Universal Flu Vaccine in the Works
A new study has demonstrated a potential strategy for developing a flu vaccine with potent, broad protection.
Immunotherapy Shows Promise for Myeloma
A strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
Immune System 'On Switch' Breakthrough Could Lead to Targeted Drugs
A crucial 'on switch' that boosts the body's defenses against infections has been successfully identified in new scientific research.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!