Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

NIH Awards $7.8 Million for Innovative HIV Vaccine Approaches

Published: Wednesday, August 22, 2012
Last Updated: Wednesday, August 22, 2012
Bookmark and Share
The grants were awarded under the Innovation for HIV Vaccine Discovery initiative, which is expected to receive up to $34.8 million over the next four years.

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded 14 grants totaling $7.8 million in first-year funding for basic research to identify new approaches for designing a safe and effective HIV vaccine.

"Recent discoveries about the basic biology of HIV and how the virus adapts to its host have provided useful information and new opportunities to guide vaccine development," said NIAID Director Anthony S. Fauci, M.D. "These grants are designed to build on that information and stimulate discovery of new ways to design a robust vaccine that prevents acquisition and establishment of latent infection."

The 14 HIV Vaccine Discovery (IHVD) grant recipient organizations include:

Altravax Inc. (Sunnyvale, Calif.)

• Principal Investigator: Robert Whalen, DSc.
• Project title: Germline-Specific Immunogens for the Induction of Neutralizing Antibodies to HIV-1.
• The initial award, supported by grant number 1R01AI10270601, is for $597,816 for fiscal year 2012.

Catholic University of America (Washington, D.C.)
• Principal Investigator: Venigalla Rao, Ph.D.
• Project title: Potent Phage T4-Derived V2 Immunogens as HIV Vaccines.
• The initial award, supported by grant number 1R01AI10272501, is for $413,787 for fiscal year 2012.

Dartmouth College (Hanover, N.H.)
• Principal Investigator: Margaret Ackerman, Ph.D.
• Project title: Applying High-Performance Protein Engineering Tools to HIV Immunogen Design.
• The initial award, supported by grant number 1R01AI10269101, is for $479,437 for fiscal year 2012.
Duke University (Durham, N.C.)
• Principal Investigator: Herman Staats, Ph.D.
• Project title: Mucosal Vaccination to Protect Against HIV-1 Infection at Mucosal Sites.
• The initial award, supported by grant number 1R01AI10274701, is for $492,072 for fiscal year 2012.
Harvard Medical School (Boston)
• Principal Investigator: Amitinder Kaur, M.D.
• Project title: Natural Killer T Cells as Modulators of AIDS Vaccine Efficacy.
• The initial award, supported by grant number 1R01AI10269301, is for $846,896 for fiscal year 2012.
Massachusetts General Hospital (Boston)
• Principal Investigator: Galit Alter, Ph.D.
• Project title: Tuning Fc-Effector Functions of HIV-Specific Antibodies.
• The initial award, supported by grant number 1R01AI10266001, is for $609,875 for fiscal year 2012.
NYU Langone Medical Center (New York City)
• Principal Investigator: Catarina Hioe, Ph.D.
• Project title: Contributions of Anti-V2 Antibodies in Protection Against HIV.
• The initial award, supported by grant number 1R01AI10274001, is for $579,543 for fiscal year 2012.
University of California (Irvine)
• Principal Investigator: Donald Forthal, M.D.
• Project title: The Impact of Antibody and pH on Female-to-Male SIV Infection.
• The initial award, supported by grant number 1R01AI10271501, is for $718,324 for fiscal year 2012.
University of Maryland (Baltimore)
• Principal Investigator: Charles Pauza, Ph.D.
• Project title: Neonatal Fc-Receptor-Targeted Mucosal HIV Vaccine.
• The initial award, supported by grant number 1R01AI10268001, is for $779,175 for fiscal year 2012.
University of Medicine and Dentistry of New Jersey (Newark)
• Principal Investigator: Abraham Pinter, Ph.D.
• Project title: Optimizing Protective Vaccine Targets in the V1/V2 Domain of HIV-1 gp120.
• The initial award, supported by grant number 1R01AI10271801, is for $566,739 for fiscal year 2012.
University of Minnesota (Minneapolis)
• Principal Investigator: Ashley Haase, M.D.
• Project title: Vaccine Design to Concentrate Protective Antibodies at the Mucosal Border.
• The initial award, supported by grant number 1R01AI10262501, is for $843,856 for fiscal year 2012.
University of North Carolina (Chapel Hill)
• Principal Investigator: Nikolay Dokholyan, Ph.D.
• Project title: Immunogen Design to Target Carbohydrate-Occluded Epitopes on the HIV envelope.
• The initial award, supported by grant number 1R01AI10273201, is for $514,331 for fiscal year 2012.
University of Rochester (Rochester, N.Y.)
• Principal Investigator: Mark Dumont, Ph.D.
• Project title: Yeast Genetic Approach to Enhance the Immunogenicity of HIV Envelope Glycoprotein.
• The initial award, supported by grant number 1R01AI10273001, is for $386,250 for fiscal year 2012.
University of Texas at El Paso
• Principal Investigator: June Kan-Mitchell, Ph.D.
• Project title: Effector and Regulatory Activities of HLA-E-restricted HIV-specific CD8 T Cells.
• The initial award, supported by grant number 1R01AI10266301, is for $531,600 for fiscal year 2012.

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Drug Might Help Treat Sepsis
A DNA enzyme called Top1 plays a key role in turning on genes that cause inflammation in mouse and human cells in response to pathogens. A drug blocking this enzyme rescued mice from lethal inflammatory responses, suggesting a potential treatment for sepsis.
Wednesday, May 18, 2016
Large-scale HIV Vaccine Trial to Launch in South Africa
NIH-funded study will test safety, efficacy of vaccine regimen.
Wednesday, May 18, 2016
New HIV Vaccine Target Discovered
NIH-Led team have discovered a new vaccine target site on HIV.
Tuesday, May 17, 2016
Finding Factors That Protect Against Flu
A clinical trial examining the body’s response to seasonal flu suggests new approaches for evaluating the effectiveness of seasonal flu vaccines.
Wednesday, April 27, 2016
Factors Influencing Influenza Vaccine Effectiveness Uncovered
The long-held approach to predicting seasonal influenza vaccine effectiveness may need to be revisited, new research suggests.
Thursday, April 21, 2016
Study Finds Factors That May Influence Influenza Vaccine Effectiveness
Researchers at NIH have suggested that the long-held approach to predicting seasonal influenza vaccine effectiveness may need to be revisited.
Wednesday, April 20, 2016
Submissions Open for the Cancer Moonshot Program
NCI opens online platform to submit ideas about research for Cancer Moonshot.
Tuesday, April 19, 2016
NIH Awards Grants to Explore Vaccine Adjuvants
NIH awards six grants to explore how combination adjuvants improve vaccines.
Wednesday, April 06, 2016
Experimental Vaccine Protects Against Dengue Virus
An experimental dengue vaccine protected all the volunteers who received it from infection with a live dengue virus.
Wednesday, March 30, 2016
Experimental Ebola Antibody Protects Monkeys
Antibody isolated from Ebola survivor can advance to clinical trials.
Friday, February 26, 2016
Dengue Vaccine Enters Phase 3 Trial
Investigational vaccine to prevent ‘breakbone fever’ developed at NIH.
Friday, January 15, 2016
In Uveitis, Bacteria in Gut May Instruct Immune Cells to Attack the Eye
NIH scientists propose novel mechanism to explain autoimmune uveitis.
Wednesday, August 19, 2015
Novel Mechanism to Explain Autoimmune Uveitis Proposed
A new study on mice suggests that bacteria in the gut may provide a kind of training ground for immune cells to attack the eye.
Wednesday, August 19, 2015
HIV Control Through Treatment Durably Prevents Heterosexual Transmission of Virus
NIH-funded trial proves suppressive antiretroviral therapy for HIV-infected people effective in protecting uninfected partners.
Tuesday, July 21, 2015
Starting Antiretroviral Treatment Early Improves Outcomes for HIV-infected Individuals
NIH-funded trial results likely will impact global treatment guidelines.
Thursday, May 28, 2015
Scientific News
Platelets are the Pathfinders for Leukocyte Extravasation During Inflammation
Findings from the study could help in the prevention and treatment of inflammatory pathologies.
Dengue Virus Exposure May Amplify Zika Infection
Researchers at Imperial College London have found that the previous exposure to the dengue virus may increase the potency of Zika infection.
Itchy Inflammation Of Mosquito Bites Helps Viruses Replicate
The itchy swelling that appears at the site of a mosquito bite isn't just an irritating nuisance - it also makes viral infections spread by the insects far worse, new research has found.
Guided Chemotherapy Missiles
Latching chemotherapy drugs onto proteins that seek out tumors could provide a new way of treating tumors in the brain or with limited blood supply that are hard to reach with traditional chemotherapy.
Revealing T-Cells in Action
Salk scientists show how T-cell receptors reposition during an immune response, revealing more on how the immune system is regulated.
Impact of Antibiotic Treatment on the Infant Gut Microbiome
Study shows that antibiotic treatment reduces stability and diversity of microbial population in the first three years of life.
Viruses Hack Their Host's Genome with CRISPR
A virus that infects major freshwater bacteria appears to use stolen bits of immune system DNA to highjack their hosts’ immune response.
Reclaiming The Immune System's Assault On Tumors
EPFL study shows a way to reclaim corrupted immune cells.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Blood Test That Detects Early Alzheimer’s Disease
A research team, led by Dr. Robert Nagele from Rowan University School of Osteopathic Medicine and Durin Technologies, Inc., has announced the development of a blood test that leverages the body’s immune response system to detect an early stage of Alzheimer’s disease – referred to as the mild cognitive impairment (MCI) stage – with unparalleled accuracy.

SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos