Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

WHEATON® Offers a Turnkey Solution for CHO Cell Bioproduction

Published: Wednesday, August 07, 2013
Last Updated: Wednesday, August 07, 2013
Bookmark and Share
WHEATON® CELLine™ Bioreactor combined with an optimized CHO medium formulation by Irvine Scientific expedites small-scale antibody and protein production.

WHEATON® and Irvine Scientific have collaborated to introduce a high yield, small-scale solution for bioproduction. The solution consists of a WHEATON® CELLine™ bioreactor flask paired with Irvine Scientific’s BalanCD™ CHO Growth A animal component-free, chemically-defined medium.

Scientists may now quickly set up and perform small-scale antibody and protein production while decreasing the cost per milligram produced. This bundled product is available now from WHEATON® and its extensive distributor network.

Antibodies and proteins for research and therapeutic purposes are typically produced in a modified cloned cell. The most widely used cells for in vitro production methods are Chinese Hamster Ovary (CHO) cells due to their stable gene expression, rapid growth, high protein production rate, and rich background of published data.

The combination of a high-throughput bioreactor, an optimized medium formulation, and an easy to follow protocol for cultivating CHO cells, provides a highly productive development platform.

WHEATON® CELLine™ Bioreactors provide an ideal growth environment for high-density cell cultures.

Cells are separated from the bulk growth medium by a dialysis membrane that regulates the flow of nutrients and waste products to and from the cell chamber.

The lower side of the cell chamber is made of a gas permeable membrane allowing continuous exchange of oxygen and carbon dioxide promoting high-density cultures.

CELLine™ bioreactor increases overall yields, and reduces use of consumables and production costs.

Irvine Scientific, a large-scale producer of advanced cell culture media, developed BalanCD™ CHO Growth A medium for optimum CHO cell growth and production.

This particular formulation, in combination with the CELLine™ bioreactor, yields antibody levels higher than conventional methods without the use of a mechanical shaker or agitation.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

WHEATON® Announces Acquisition of CELLine™
WHEATON has acquired the CELLine bioreactor flask line for antibody and protein production from Wilson Wolf Manufacturing Corporation.
Tuesday, July 10, 2012
Scientific News
Shedding Light on HIV Vaccine Design
Broadly speaking - Mathematical modelling of host-pathogen coevolution sheds light on HIV vaccine design.
Progress In Vaccination Against Vespid Venom
Researchers at the Helmholtz Zentrum München and the Technical University Munich have presented a method which facilitates a personalised procedure for wasp allergy sufferers.
New Drug Target for Inflammatory Disorders
Penn study finds enigmatic molecules maintain equilibrium between fighting infection and inflammatory havoc.
Oxygen Can Impair Cancer Immunotherapy
Researchers have identified a mechanism within the lungs where anticancer immune resposnse is inhibited.
LncRNAs Maintain Immune Health
Long non-coding RNAs are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders.
Researchers Identify Influenza Fighting Molecule
St. Jude scientists have identified the molecule that recognizes influenza virus cells and triggers their death to fight the infection.
Breast Milk Sugar May Protect Babies Against Deadly Infection
Researchers from Imperial College London find that a sugar found in some women’s breast milk may protect babies against Group B streptococcus.
New Method of Cancer Immunotherapy
Stanford chemists have dicovered a new form of cancer immunotherapy using sugar presence manipulation.
Immune Breakthrough: Unscratching Poison Ivy’s Rash
Researchers from Monash University have discovered the molecular cause of poison ivy rash.
Alien-Like Reproduction of Single-Celled Fungi
Biologists have directly observed how microspridia, a single-celled fungi, replicate and spread.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!