Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

BioGenes Launches Enhanced Generic HCP Assay

Published: Wednesday, September 18, 2013
Last Updated: Wednesday, September 18, 2013
Bookmark and Share
CHO|360-HCP ELISA for early stage biologics production.

BioGenes GmbH has announced that it has launched a new generic HCP assay with enhanced HCP recovery properties.

The CHO|360-HCP ELISA is designed to cover the broadest possible spectrum of antigens by integrating four different assay types.

An upfront feasibility test will identify the most suitable ELISA kit thus allowing to greatly increasing HCP recovery.

CHO|360-HCP ELISAs employ antibodies of HCPs from different species. By immunizing rabbits and goats with HCPs of a non-transfected CHO cell line combined with a unique approach for antigen and antibody preparation as well as an optimized purification strategy, BioGenes has developed a panel of four different HCP ELISAs that altogether build up the enhanced generic CHO|360-HCP Assay.

Dagmar Schwertner-Knoll, Marketing Director of BioGenes GmbH said: “Our strategy is to offer different ELISA kits for HCP detection. An upfront feasibility test, performed by the customer or by BioGenes as a service, enables the selection of the most suitable kit for a specific process and greatly increases the HCP recovery for most samples.”

For all four assay types the lower limit of detection (LOD) is between 0.5–1 ng/ml and the lower limit of quantification (LOQ) is 2–3 ng/ml with a working range between 2–100 ng/ml.

A high specificity for the antigen in all four assays was determined by 2D western blotting with the respective antibodies.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

BioGenes Reports Strong Growth of HCP Assay Development Business
Company is developing pre-optimized HCP assay kits.
Thursday, February 28, 2013
BioGenes to Develop Specific HCP Assay for Boehringer Ingelheim
HCP assays usually required in clinical phase III studies to demonstrate consistency of manufacturing.
Friday, June 15, 2012
BioGenes Has Developed Cellmid’s Midkine Blood Test and Reports Manufacture of First Kits
BioGenes GmbH, a supplier of GMP compliant immunoassay and antibody services, has developed and optimized the first ever fully validated ELISA protocol for Midkine detection in blood serum.
Tuesday, November 16, 2010
Scientific News
Inciting an Immune Attack on Cancer Cells
A new minimally invasive vaccine that combines cancer cells and immune-enhancing factors could be used clinically to launch a destructive attack on tumors.
Inflammation Linked to Colon Cancer Metastasis
A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.
New Strategy for Combating Adenoviruses
Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans.
Major Advance Toward More Effective, Long-Lasting Flu Vaccine
Collaboration shows vaccine candidate can produce powerful ‘broadly neutralizing antibodies’ in animal models.
Immune System: Help for Killer Cells
A study from the University of Bonn may show the way to more effective vaccines.
Protein Found to Control Inflammatory Response
A new Northwestern Medicine study shows that a protein called POP1 prevents severe inflammation and, potentially, diseases caused by excessive inflammatory responses.
A Leap Forward in Vaccinating Against HIV
A team of scientists has developed an experimental vaccine candidate that successfully stimulates the immune system activity in animal models necessary to stop HIV infection.
MRI Scanners Can Steer Therapeutics to Specific Target Sites
Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.
Agricultural Intervention Improves HIV Outcomes
A multifaceted farming intervention can reduce food insecurity while improving HIV outcomes in patients in Kenya, according to a randomized, controlled trial led by researchers at UC San Francisco.
Team Finds Early Inflammatory Response Paralyzes T Cells
Findings could have enormous implications for immunotherapy, autoimmune disorders, transplants and other aspects of immunity.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!