Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Cell Therapy Company Uses TAP’s Fill-It Automated Cryovial Processing System

Published: Thursday, December 05, 2013
Last Updated: Wednesday, December 04, 2013
Bookmark and Share
To rapidly produce consistent cancer immunotherapy batches and cell banks.

TAP Biosystems has announced that its Fill-It™, automated benchtop vial filling system is being routinely used at an innovative cell therapy company developing novel cancer immunotherapies, to improve processing speed and throughput of large batches of cells in cryovials for use as master cell banks or as cell-based immunotherapies.

Scientists at the company are using Fill-It to produce batches of around 1000 cryovials per run, containing 0.65ml of up to 100 million cell/ml of an immunotherapy product candidate, consisting of two allogeneic cancer cell lines.

Fill-It aseptically processes these temperature-sensitive cells at high throughput, enabling vials to be uncapped, filled and recapped at speed, so they can be put them in the freezer quickly to maintain optimum cell quality.

Stephen Guy, Fill-It Product Manager at TAP, explained: “The company wanted to automate their vial processing as it was taking around one and half hours for a scientist to produce a batch of 1000 vials. As well as the RSI issues associated with uncapping and recapping this number of vials, it was difficult to maintain product consistency across the batch. Using the Fill-It automated system, batches of vials are processed at speed with minimal human interaction. The cells are dispensed using sterile, GMP-certified disposable tubing and the vials get into the freezer quickly. This results in cell numbers being maintained at consistently high quality until the vials are thawed for use.”

Guy added: “We are delighted our Fill-It system is helping such an innovative cell therapy company to ensure their critical cancer cell banks and cancer immunotherapies are maintained in top condition. This firm’s routine application of our technology demonstrates to cell therapy companies looking for a method of rapidly producing large batches of consistent quality cells that a Fill-It system is a tried and trusted choice.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Boosting Breast Cancer Treatment
To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years.
Research Finding Could Lead to Targeted Therapies for IBD
Findings published online in Cell Reports.
A Cellular Symphony Responsible for Autoimmune Disease
Broad Institute researchers have used a novel approach to increase our understanding of the immune system as a whole.
Genetic Basis of Fatal Flu Side Effect Discovered
A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a recent study.
Developing Drug Resistance may be a Matter of Diversity for Tuberculosis
Researchers have probed the bacteria that causes tuberculosis, Mycobacterium tuberculosis, to learn more about how individual bacterial cells change and adapt while in the human body.
Surprising Trait Found in Anti-HIV Antibodies
Scientists at The Scripps Research Institute (TSRI) have new weapons in the fight against HIV.
Some Gut Microbes May Be Keystones of Health
University of Oregon scientists have found that strength in numbers doesn’t hold true for microbes in the intestines. A minority population of the right type might hold the key to regulating good health.
Essential Component of Antiviral Defense Identified
Infectious disease researchers at the University of Georgia have identified a signaling protein critical for host defense against influenza infection.
Single Vaccine for Chikungunya, Related Viruses May be Possible
What if a single vaccine could protect people from infection by many different viruses? That concept is a step closer to reality.
Is Allergy the Price We Pay for Our Immunity to Parasites?
New findings help demonstrate the evolutionary basis for allergy.

SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos