Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Flu Sends Scientists Dipping for Gold

Published: Wednesday, December 11, 2013
Last Updated: Wednesday, December 11, 2013
Bookmark and Share
Researchers on the Norwich Research Park have patented a quick, simple dipstick flu test using sugar labelled with gold.

Quick diagnosis of flu is important because vaccination and antiviral drugs need to be administered to patients within 48 hours of infection to prevent new pandemics arising.

“We are now looking for a diagnostics company to help us bring it to market,” said Professor Rob Field from the John Innes Centre.

He and Professor David Russell from the University of East Anglia found that a gold solution changes colour in the presence of the flu virus. And the colour it changes to differs according to the strain of flu.

Results published in Organic & Biomolecular Chemistry show that gold nanoparticles can be used to detect the human influenza virus X31 (H3N2) within 30 minutes and to distinguish between human and avian influenza.

Prof Field explains that 90% of human infections use carbohydrate recognition to bind with targets in the body. The sensor is a suspension of sugars tagged with gold particles. If the flu virus is present, it will attach to a sugar, pulling particles closer together. Human and avian flu have a preference for different sugar chains resulting in a colour change visible to the naked eye.

“The same basic principles can be applied wherever rapid detection is required from detecting superbugs in hospitals to biohazards such as ricin,” said Professor Field.

The researchers have already developed a carbohydrate-based sensor to detect cholera in contaminated water supplies.

“Our technique based on gold nanoparticles is much faster than current methods of detection,” said Professor Russell from UEA.

Professor Russell leads a spinout company, Intelligent Fingerprinting, based on drug and drug metabolite screening using the sweat contained in fingerprints. Government funding is being used to develop a patented handheld device for use in Accident and Emergency and coroner services.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Unique Mechanism for a High-Risk Leukemia
Researchers uncovered the aberrant mechanism underlying a notoriously treatment-resistant acute lymphoblastic leukemia subtype; findings offer lessons for understanding all cancers.
Food Triggers Creation of Regulatory T Cells
IBS researchers document how normal diet establishes immune tolerance conditions in the small intestine.
Therapeutic Approach Gives Hope for Multiple Myeloma
A new therapeutic approach tested by a team from Maisonneuve-Rosemont Hospital (CIUSSS-EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a cancer of the bone marrow currently considered incurable with conventional chemotherapy and for which the average life expectancy is about 6 or 7 years.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
Switch Lets Salmonella Fight, Evade Immune System
Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm.
Tricked-Out Immune Cells Could Attack Cancer
New cell-engineering technique may lead to precision immunotherapies.
Neural Networks Adapt to the Presence of a Toxic HIV Protein
HIV-associated neurocognitive disorders (HAND) afflict approximately half of HIV infected patients.
HIV Protein Manipulates Hundreds of Human Genes
Findings search for new or improved treatments for patients with AIDS.
Breaking the Brain’s Garbage Disposal
The children’s ataxia gene problem turned out to be not such a big deal genetically — it was such a slight mutation that it barely changed the way the cells made the protein.
Flesh-Eating Bacteria Work Together
Scientists recently discovered different strains of deadly flesh-eating bacteria working together to spread infection and they now have a better understanding of the role of the toxins they produce. The discovery could change how the illness and other diseases are treated.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!