Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Debiopharm, Yale University Extend Collaboration

Published: Wednesday, May 07, 2014
Last Updated: Wednesday, May 07, 2014
Bookmark and Share
New license and research agreement regarding the discovery of MIF inhibitors.

Debiopharm Group™ (Debiopharm) has announced that it has signed a new license and research agreement with Yale University (Yale), a premier university with a long tradition of basic and clinical biomedical research, regarding the discovery of MIF inhibitors for treatment of autoimmune and inflammatory diseases.

This joint effort will enable the discovery and development of potential oral first-in-class compounds that inhibit Macrophage Migration Inhibitory Factor (MIF), a key regulatory cytokine that has been linked genetically to the pathogenesis of several autoimmune and inflammatory diseases.

“We are very pleased to announce this new research collaboration with top-ranked Yale University. We are convinced that building a strong relationship with leading, medically-focused academic institutions is a productive way of creating drugs for tomorrow” said Thierry Mauvernay, Delegate of the Board, Debiopharm Group.

Yale researchers Richard Bucala, MD, PhD, Professor of Medicine, Epidemiology and Pathology, and William L. Jorgensen, PhD, Sterling Professor of Chemistry and Director of the Division of Physical Sciences and Engineering, are leading the Yale scientific team designing small molecule antagonists to block inflammation in patients.

“Debiopharm’s reputation for early stage drug development is well known, and this is an exciting new therapeutic approach that may ultimately allow us to tailor treatment to a patient’s immunogenetic profile,” said Bucala.

“The project is progressing well with great synergies between computer-aided molecular design, synthetic chemistry, crystallography and biology,” Jorgensen added. “We are delighted with Debiopharm's participation, which is essential for spearheading the preclinical and clinical efforts.”

"This is a great example of how scientists of academia and industry can put their efforts together to bring solutions to pressing medical needs in a more efficient manner" added Andrés McAllister, Chief Scientific Officer, Debiopharm International SA.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Go To Market Consulting and Debiopharm Collaborate
Collaboration to identify early stage in-licensing opportunities on the US West Coast.
Friday, September 27, 2013
Scientific News
Breakthrough Flu Vaccine Inhibited by Pre-existing Antibodies
Universal truths – how existing antibodies are sabotaging the most promising new human flu vaccines.
Zika Vaccine Candidates Show Promise
Two experimental vaccines have shown promise against a major viral strain responsible for the Brazilian Zika outbreak.
Antibody Drug Shows Promise in HIV Treatment
Researchers are a step closer to an alternative HIV treatment that has the potential for lasting effects and less frequent dosing.
Targeting Autoimmunity
Researchers have developed a strategy to treat a rare autoimmune disease which could lead to treatments of other autoimmune diseases.
Flu Vaccine May Reduce Death Risk of Type 2 Diabetes
New research suggests that a new flu vaccine may reduce probability of type 2 diabetes patients being hospitalised with stroke and heart failure.
Gut Bacteria Older than Human Species
Some bacteria have lived in the human gut since before we were human, suggesting evolution could have a larger role inhuman bacterial makeup.
Evidence of Mosquito Transmitting Zika
A direct link between the Yellow fever mosquito and Zika transmission has been found following investigation into selective mosquito control.
Antibody-Based Drug for Multiple Sclerosis
New antibody-based drug paves the way for new strategies for controlling and treating multiple sclerosis.
Three-Drug Combinations Counter Antibiotic Resistance
Research shows that combinations of three different antibiotics can treat resistant bacteria, even if they are ineffective independently.
Mapping Zika’s Routes to Developing Fetus
UC researchers show how Zika virus travels from a pregnant woman to her fetus, and also identified a drug that could stop it.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!