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Association between asthma-related emergency department visits, meteorological measurements, and air quality concentrations in the Bronx (2001-2008)
Abraham R(1), Toh J(2), Desai T(2), Shum M(3), Patel P(2), Rosenstreich D(2), Jariwala SP(2)

Evaluate the association between asthma-related emergency department visits (AREDV), meteorological measurements, and air quality concentrations in a high asthma prevalence area, the New York City borough of the Bronx.

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Ocular papillary changes on the caruncle surface in allergic conjunctivitis
Milton M. Hom, OD, FAAO1, Leslie E. O’Dell, OD, FAAO2, Carl J. May, Jr., MD2, Leonard Bielory, MD3

The caruncle is small, pink, globular nodule at the inner corner of the eye. We found the papillary changes of the caruncle corresponds to changes in palpebral conjunctiva seen in allergic conjunctivitis. There may indicate a greater inflammatory response in the caruncle resulting in greater itching in the nasal corners of the eye. Allergists can easily assess the caruncle.

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Microbial Regulation of IgE Production in Early Life
Ana B Blazquez, Jeremiah J Faith, Hugh A Sampson, M Cecilia Berin

Changes in gastrointestinal microbiota have been suggested to drive the increasing prevalence of food allergy. Our aim was to determine the impact of mouse and human intestinal microbiota on modulation of allergic parameters including IgE.

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Tolerance to Allergenic Foods Following Food Oral Immunotherapy (FOIT)
AR Hague1, RL Wasserman1,2, SK Silvers1,2, RW Sugerman1,2, M Herbert3

We report on 21 patients who completed FOIT (food oral immunotherapy) escalation followed by a period of maintenance dosing and later underwent a tolerance FC (food challenge). 90% of tested FOIT patients and 94% of patients who met our pre-defined criteria for tolerance FC achieved tolerance to their allergenic food.

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Single Practice Six-Year Experience Treating Food Allergy With Oral Immunotherapy
DM Pence1, AR Hague1, RL Wasserman1,2, SK Silvers1,2, RW Sugerman1,2, M Herbert3

We report a more-than-six-year experience with food oral immunotherapy (FOIT) in a private allergy practice setting. Most patients can be desensitized to one or more allergenic foods. Ongoing evaluation and modification of the FOIT procedures improves outcomes and acceptability. FOIT can be successfully performed in an allergy office.

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Peanut Allergy: An epidemiologic analysis of a large database
Leickly, FE, Vitapur, G, and Kloepfer, K

Over three years, 700 children with a peanut story - either peanut sensitization or peanut allergy- were asked to participate in a database.

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Increasing the Generalization Capability of Biomarkers Through Systems Biology Malaria Vaccines Case Study
Simón Perera del Rosario 1, Raquel Valls 1, Gemma Moncunill 2, Teresa Sardón 1, Carlota Dobaño 2, José Manuel Mas 1

The results underline the utility of Systems Biology (and specially Anaxomics’s TPMS) for the interpretation of high-throughput data in BM identification, with a better generalization capability than conventional methods.

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Apoplastic Venom Allergen‐like Proteins of Cyst Nematodes Modulate the Activation of Basal Plant Innate Immunity by Cell Surface Receptors
Jose L. Lozano-Torresa, Ruud H.P. Wilbersa, SonjaWarmerdama, Anna Finkers-Tomczaka, Amalia Diaz-Granadosa, Casper C. van Schaika, Johannes Heldera, Jaap Bakkera,b, Aska Goversea,b, Arjen Schotsa and Geert Smanta,b

We conclude that parasitic nematodes most likely utilize VAPs to suppress the activation of defenses by immunogenic breakdown products in damaged host tissue.

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Non-disruptively Count and Quantify Fluorescent iPS Colonies During Secondary Reprogramming: 7 min per 6-well Plate, Dual-fluorescence Whole Well Imaging Cytometry
SC Cribbes, S Brightwell, K Kaji

Nexcelom’s Celigo imaging cytometer has been applied to provide automated, rapid assessment of iPS reprogramming.

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Showing Results 11 - 20 of 51
Scientific News
Genetic Mutation Helps Explain Why, In Rare Cases, Flu Can Kill
Study shows that immune response to flu can be affected by a rare genetic mutation.
Honey Bees Use Multiple Genetic Pathways To Fight Infections
The findings may help scientists develop honey bee treatments that are tailored to specific types of infections.
HBV Exposure Matures Infants’ Immune Systems
Findings presents a paradigm shift in the approach to treatment of patients with chronic hepatitis B.
For Most Children with HIV and Low Immune Cell Count, Cells Rebound After Treatment
NIH-funded study finds T-cell level returns to normal with time.
Strengthening the Immune System’s Fight Against Brain Cancer
NIH-funded research suggests novel way to improve vaccine efficacy in brain tumors.
Surprising Finding In Stroke Research
Scientists at The University of Manchester have made an important new discovery about the brain’s immune system that could lead to potential new treatments for stroke and other related conditions.
Macrophages May Play Critical Role in Melanoma Resistance to BRAF Inhibitors
Discovery could lead to a new melanoma target.
Autoimmune Disease Super-Regulators Uncovered
Scientists discovered key genetic switches, called super-enhancers, involved in regulating the human immune system.
Gene Discovery Provides Clues To How TB May Evade The Immune System
The largest genetic study of TB susceptibility to date has led to a potentially important new insight into how the pathogen manages to evade the immune system.
Tetanus Shot Improves Patient Survival With Brain Tumor Immunotherapy
Study shows patient survival increased when the immune system was primed with a tetanus booster.
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