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Saturday, May 25, 2013
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Investigating Viral dynamics
Sukhdeep Singh

Analysis of SIV next generation sequencing data for the estimation of escape rates in different animal groups and tissue compartments.

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Hepatitis B virus (HBV) and Human immunodeficiency virus (HIV) antibodies detected by peptide microarrays
ahmed Abd El Wahed1, Ulrike Beutling2, Ronald Frank2, Gerhard Hunsmann1, and Hans-Joachim Fritz3

HBV and HIVenv chips with overlapping oligopeptides encompassing the full amino acid sequences of HBV and HIV polypeptides were produced. In addition, a chip displaying a library of random 4608 different 15-mers peptides (4608-RPL) was prepared. Both chips were used for analyzing monoclonal antibodies and sera from HIV- and HBV-infected individuals. 4608-RPL could be used for identifying target sequences of antibodies without prior knowledge of the corresponding immunizing antigen.

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Scientific News
Common Childhood Asthma Not Rooted in Allergens, Inflammation
Discovery of origins of a unique form of asthma may lead to a precision medicine approach to treatment.
Infection Makes Mosquitoes Immune to Malaria Parasites
Study highlights the potential of using Wolbachia in malaria control.
Depression Linked to Telomere Enzyme, Aging, Chronic Disease
The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain.
Program for Breakthrough Biomedical Research to Celebrate 15 Years
A program that fosters basic science projects of potentially high impact is celebrating 15 years of discovery at UC San Francisco.
Osteoarthritis Progression Halted in Mice
If successful in humans, joint replacement surgery might be avoidable.
Vitamin D Could Provide New and Effective Treatments for Asthma
Vitamin D has the potential to significantly reduce the symptoms of asthma, according to a new study from the Medical Research Council (MRC).
Nuvo Research Announces Scientific Presentation at the Annual Meeting of AAI
Data evaluating WF10's therapeutic impact on signs and symptoms of experimentally induced rheumatoid arthritis in mice.
Yale Cancer Center Carves New Path in Immunotherapy
Cancer immunotherapy is showing promise in treating patients with a variety of advanced, metastatic tumors.
UCSF Scientists Use Human Stem Cells to Generate Immune System in Mice
Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory.
Hormone May Help Treat Diabetes
Betatrophin prompts cells in the pancreas to multiply and produce more insulin.
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