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Marked increase in basophil activation during non-anaphylactic allergic reactions to peanut in man
Paul J. Turner, Orla McMahon, Amy Switzer, Andrew Clark, Robert J. Boyle, Stephen R. Durham and Mohamed H. Shamji

Our data imply an important role for basophils in the evolution of acute IgE-mediated reactions to food allergens.

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Ten-Year Experience with Sublingual Immunotherapy for Juniper Pollenosis
W Donald Cooke MD

Efficacy of sublingual immunotherapy for Juniper induced allergic rhinitis is presented.

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Association between asthma-related emergency department visits, meteorological measurements, and air quality concentrations in the Bronx (2001-2008)
Abraham R(1), Toh J(2), Desai T(2), Shum M(3), Patel P(2), Rosenstreich D(2), Jariwala SP(2)

Evaluate the association between asthma-related emergency department visits (AREDV), meteorological measurements, and air quality concentrations in a high asthma prevalence area, the New York City borough of the Bronx.

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Ocular papillary changes on the caruncle surface in allergic conjunctivitis
Milton M. Hom, OD, FAAO1, Leslie E. O’Dell, OD, FAAO2, Carl J. May, Jr., MD2, Leonard Bielory, MD3

The caruncle is small, pink, globular nodule at the inner corner of the eye. We found the papillary changes of the caruncle corresponds to changes in palpebral conjunctiva seen in allergic conjunctivitis. There may indicate a greater inflammatory response in the caruncle resulting in greater itching in the nasal corners of the eye. Allergists can easily assess the caruncle.

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Microbial Regulation of IgE Production in Early Life
Ana B Blazquez, Jeremiah J Faith, Hugh A Sampson, M Cecilia Berin

Changes in gastrointestinal microbiota have been suggested to drive the increasing prevalence of food allergy. Our aim was to determine the impact of mouse and human intestinal microbiota on modulation of allergic parameters including IgE.

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Tolerance to Allergenic Foods Following Food Oral Immunotherapy (FOIT)
AR Hague1, RL Wasserman1,2, SK Silvers1,2, RW Sugerman1,2, M Herbert3

We report on 21 patients who completed FOIT (food oral immunotherapy) escalation followed by a period of maintenance dosing and later underwent a tolerance FC (food challenge). 90% of tested FOIT patients and 94% of patients who met our pre-defined criteria for tolerance FC achieved tolerance to their allergenic food.

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Single Practice Six-Year Experience Treating Food Allergy With Oral Immunotherapy
DM Pence1, AR Hague1, RL Wasserman1,2, SK Silvers1,2, RW Sugerman1,2, M Herbert3

We report a more-than-six-year experience with food oral immunotherapy (FOIT) in a private allergy practice setting. Most patients can be desensitized to one or more allergenic foods. Ongoing evaluation and modification of the FOIT procedures improves outcomes and acceptability. FOIT can be successfully performed in an allergy office.

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Peanut Allergy: An epidemiologic analysis of a large database
Leickly, FE, Vitapur, G, and Kloepfer, K

Over three years, 700 children with a peanut story - either peanut sensitization or peanut allergy- were asked to participate in a database.

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Increasing the Generalization Capability of Biomarkers Through Systems Biology Malaria Vaccines Case Study
Simón Perera del Rosario 1, Raquel Valls 1, Gemma Moncunill 2, Teresa Sardón 1, Carlota Dobaño 2, José Manuel Mas 1

The results underline the utility of Systems Biology (and specially Anaxomics’s TPMS) for the interpretation of high-throughput data in BM identification, with a better generalization capability than conventional methods.

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Showing Results 11 - 20 of 55
Scientific News
Inciting an Immune Attack On Cancer Cells
A new minimally invasive vaccine that combines cancer cells and immune-enhancing factors could be used clinically to launch a destructive attack on tumors.
Inciting an Immune Attack on Cancer Cells
A new minimally invasive vaccine that combines cancer cells and immune-enhancing factors could be used clinically to launch a destructive attack on tumors.
Inflammation Linked to Colon Cancer Metastasis
A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.
New Strategy for Combating Adenoviruses
Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans.
Major Advance Toward More Effective, Long-Lasting Flu Vaccine
Collaboration shows vaccine candidate can produce powerful ‘broadly neutralizing antibodies’ in animal models.
Immune System: Help for Killer Cells
A study from the University of Bonn may show the way to more effective vaccines.
Protein Found to Control Inflammatory Response
A new Northwestern Medicine study shows that a protein called POP1 prevents severe inflammation and, potentially, diseases caused by excessive inflammatory responses.
A Leap Forward in Vaccinating Against HIV
A team of scientists has developed an experimental vaccine candidate that successfully stimulates the immune system activity in animal models necessary to stop HIV infection.
MRI Scanners Can Steer Therapeutics to Specific Target Sites
Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.
Agricultural Intervention Improves HIV Outcomes
A multifaceted farming intervention can reduce food insecurity while improving HIV outcomes in patients in Kenya, according to a randomized, controlled trial led by researchers at UC San Francisco.
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