|THE MASTOCYTOSIS SOCIETY SURVEY ON MAST CELL DISORDERS: Part 2-Clinical Experiences, Co-Morbidities, Diet, Families and Opinions|
aNancyRussell, DrPH, aSusanJennings, PhD, aBlairJennings, BS, aValerie Slee , RN, BSN, aLisa Sterling, BS, bMariana Castells, MD, PhD, FAAAAI,cPeter Valent, MD, bCem Akin, MD, PhD, FAAAAI
Mast cell diseases such as mastocytosis and mast cell activation syndromes involve abnormal proliferation or activation of these cells leading to many potentially debilitating symptoms. In order to determine the characteristics and experiences of people known or suspected to have a mast cell disorder, The Mastocytosis Society (TMS), a U.S. based patient advocacy, research and education organization, conducted a survey of patients.
|Safety Of A Sublingual Tablet of House Dust Mite Allergen Extracts In An Environmental Exposure Chamber Study|
Michel Roux, Agnès Viatte, Robert K. Zeldin
In an environmental exposure chamber (EEC) study, treatment with HDM sublingual tablets in patients with HDM-associated allergic rhinitis was generally well tolerated regardless of dose. While asthma and related symptoms were more common during the peri-EEC challenge periods, rates did not differ between active and placebo treatment.
|Safety Of The 300 IR and 500 IR Doses Of A House Dust Mite Allergen Extracts Sublingual Tablet In Adults with Allergic Rhinitis|
Hélène Nguyen, Michel Roux, Josiane Cognet-Sicé, Robert K. Zeldin
In a randomized, DBPC study in patients with HDM-associated allergic rhinitis, treatment with HDM sublingual tablets at doses of 300IR and 500IR was associated with a favorable safety profile. There was no appreciable difference in tolerability between the tested doses.
|Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge TheatreTM|
Suzanne Kelly, PHD;Jacob Karsh, MDCM, FRCPC; Jimmy Yang, MBA; William H. Yang, MD, FRCPC, FAAAAI
Response to ragweed allergen provocation in the Red Maple Trials Allergen Challenge Theatre
|Field Performance of a New Technology with the Potential to Identify Allergy and Asthma Triggers|
Julian Gordon, PhD, Prasanthi Gandhi, MBA, MPH1, Jack A.Gilbert, Jarrad T. Hampton-Marcell
This work introduces a very simple plug-and-play device that can sample air at a high volume flow rate with no moving parts. Aerosol particles are captured on electrodes and eluted for testing. We show that performance of the device is substantially equivalent to capture by pumping through a filter for immunological and molecular analysis.
|Marked increase in basophil activation during non-anaphylactic allergic reactions to peanut in man|
Paul J. Turner, Orla McMahon, Amy Switzer, Andrew Clark, Robert J. Boyle, Stephen R. Durham and Mohamed H. Shamji
Our data imply an important role for basophils in the evolution of acute IgE-mediated reactions to food allergens.
|Ten-Year Experience with Sublingual Immunotherapy for Juniper Pollenosis|
W Donald Cooke MD
Efficacy of sublingual immunotherapy for Juniper induced allergic rhinitis is presented.
|Association between asthma-related emergency department visits, meteorological measurements, and air quality concentrations in the Bronx (2001-2008)|
Abraham R(1), Toh J(2), Desai T(2), Shum M(3), Patel P(2), Rosenstreich D(2), Jariwala SP(2)
Evaluate the association between asthma-related emergency department visits (AREDV), meteorological measurements, and air quality concentrations in a high asthma prevalence area, the New York City borough of the Bronx.
|Ocular papillary changes on the caruncle surface in allergic conjunctivitis|
Milton M. Hom, OD, FAAO1, Leslie E. O’Dell, OD, FAAO2, Carl J. May, Jr., MD2, Leonard Bielory, MD3
The caruncle is small, pink, globular nodule at the inner corner of the eye. We found the papillary changes of the caruncle corresponds to changes in palpebral conjunctiva seen in allergic conjunctivitis. There may indicate a greater inflammatory response in the caruncle resulting in greater itching in the nasal corners of the eye. Allergists can easily assess the caruncle.
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