Corporate Banner
Satellite Banner
Immunology
Scientific Community
 
Become a Member | Sign in
Home>Products>This Product
  Products


MaxDiscovery™ Human IL-11 ELISA Test Kit

Product Description
The MaxDiscovery™ Human IL-11 ELISA Test Kit is designed for quantitative determination of the concentration of human IL-11 in serum, plasma, and cell culture supernatant. Human interleukin 11 (IL-11), also known as adipogenesis inhibitory factor (AGIF) and oprelvekin, is a highly conserved 19 kDa protein of 178 amino acids after cleavage of the first 21 amino acid signal peptide. IL-11 is thermally stable and contains neither cysteine residues nor N-glycosylation sites. IL-11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multi-subunit receptor complexes containing at least one gp130. IL-11 exerts biological activity through IL-11 receptor by utilizing the gp130 molecule as the signaling component of its receptor. Many cell and tissue types throughout the body, such as CNS, thymus, lung, bone, connective tissues, uterus, skin, and testis, can produce IL-11 depending on the local environment of the cell or tissue. IL-11 promotes primary and secondary immune responses in vitro and in vivo and modulates antigen-specific antibody reactions. IL-11 has activity in bone metabolism and activity in protection and restoration of the gastrointestinal mucosa. Human endometrial stromal cells produce biologically active IL-11, which promotes progesterone-induced decidualization. Therefore, the IL-11 has both paracrine and autocrine actions on human endometrial stromal cells and plays an important role in preparing the human endometrium for implantation. Reports indicate that abnormal IL-11 levels in serum or plasma is related to immune thrombocytopenia, rheumatoid arthritis, and urogenital infection. Immunoreactive IL-11 has also been linked to aseptic loosening of total hip replacement implants. The production of IL-11 is elevated in lesional skin organ cultures of patients with active plaque-type psoriasis as compared with non-lesional and normal skin.
Product MaxDiscovery™ Human IL-11 ELISA Test Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 2119-01
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122
Email: info@biooscientific.com



Scientific News
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Slime Mold Reveals Clues to Immune Cells’ Directional Abilities
Study from UC San Diego identifies a protein involved in the directional ability of a slime mold.
Supressing Intenstinal Analphylaxis in Peanut Allergy
Study from National Jewish Health shows that blockade of histamine receptors suppresses intestinal anaphylaxis in peanut allergy.
Getting a Better Look at How HIV Infects and Takes Over its Host Cells
A new approach, developed by a team of researchers led by The Rockefeller University and The Aaron Diamond AIDS Research Center (ADARC), offers an unprecedented view of how a virus infects and appropriates a host cell, step by step.
Untangling Disease-Related Protein Misfolding
Work advances understanding of genetic forms of thrombosis, emphysema, cirrhosis of the liver, neurodegenerative diseases and inflammation, among others.
Developing a More Precise Seasonal Flu Vaccine
During the 2014-15 flu season, the poor match between the virus used to make the world’s vaccine stocks and the circulating seasonal virus yielded a vaccine that was less than 20 percent effective.
Fighting Cancer with Borrowed Immunity
A new step in cancer immunotherapy: researchers from the Netherlands Cancer Institute and University of Oslo/Oslo University Hospital show that even if one's own immune cells cannot recognize and fight their tumors, someone else's immune cells might.
Loss Of Y Chromosome Increases Risk Of Alzheimer’s
Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at risk of developing Alzheimer’s disease.
Immune Cells Remember Their First Meal
Scientists at the University of Bristol have identified the trigger for immune cells' inflammatory response – a discovery that may pave the way for new treatments for many human diseases.
"Sunscreen" Gene May Guard Against Melanoma
USC-led study reveals that melanoma patients with deficient or mutant copies of the gene are less protected from harmful ultraviolet rays.

SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!