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 | Library Design for Tackling Protein-protein Interactions: The 2P2I Approacha Dr Philippe Roche, CNRS, speaking at Discovery Chemistry Congress 2013. |
 | Deep Metagenomic Sequencing of Multiple Ruminant Guts Reveals Species-specific Microbiomes Mick Watson, University of Edinburgh, speaking at Genomics Research 2013. |
Benchtop Automation Trends 2013
HTStec
This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
Top 10 Drug Discovery Technologies - Strategic Analysis and Global Forecasts
MarketsandMarkets
The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs. The applications of these technologies in the introduction of drugs have created significant opportunities for market growth. The slow introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.
Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014)
MarketsandMarkets
The market for bioinformatics platforms is growing at a significant pace with the increasing demand from U.S. and Europe. This trend is supported by the increasing demand for sequencing platforms with increasing life science research using techniques such as gene expression analysis, sequence analysis, and protein expression analysis.
The Global Bioinformatics Market: Market size, forecasts and company profiles
Business Insights
This report provides analysis of bioinformatics market over three major segments, namely tools, content/database and service. It further analyzes each macro market with respect to sub segments from the market prospective. It also gives a qualitative and quantitative view of the bioinformatics market over major geographical regions.
HTStec
This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
Top 10 Drug Discovery Technologies - Strategic Analysis and Global Forecasts
MarketsandMarkets
The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs. The applications of these technologies in the introduction of drugs have created significant opportunities for market growth. The slow introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.
Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014)
MarketsandMarkets
The market for bioinformatics platforms is growing at a significant pace with the increasing demand from U.S. and Europe. This trend is supported by the increasing demand for sequencing platforms with increasing life science research using techniques such as gene expression analysis, sequence analysis, and protein expression analysis.
The Global Bioinformatics Market: Market size, forecasts and company profiles
Business Insights
This report provides analysis of bioinformatics market over three major segments, namely tools, content/database and service. It further analyzes each macro market with respect to sub segments from the market prospective. It also gives a qualitative and quantitative view of the bioinformatics market over major geographical regions.
Indiana Biosciences Research Institute Unveiled
Purdue University part of first industry-led collaborative life sciences research institute in the United States.
Molecular Modelling to Help Create Better, Safer Drugs
How our bodies break down the common drugs ibuprofen, diclofenac and warfarin is the subject of a new study from the University of Bristol.
ATARiS Informatics Platform Hits the Jackpot
ATARiS is one of several tools developed at the Broad Institute to precisely tune in to the signals within noisy datasets.
New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure
Computational Tool Translates Complex Data into 2-Dimensional Images
May allow doctors to track progression of cancer, response to treatment, and risk of relapse.
Agilent Technologies Announces Winner of Fifth Annual Early Career Professor Award
Assistant Professor at Northwestern Recognized for Cancer Diagnostics Research.
Launch of £90m Initiative in Big Data and Drug Discovery at Oxford University
'Big data' to revolutionise healthcare.
HealthLinkNow Integrates SBR Health
HLN and SBR announced HLN has selected SBR’s video call routing and management solution to manage virtual patient-provider visits on HLN’s telemedicine network.
Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines
NIAID-funded investigators develop interactive web applications to share data with peers.
Gifts to Boost University of Chicago as Hub for Biomedical 'Big Data'
Two major gifts will build momentum behind the University of Chicago’s leadership in biomedical computation.
Purdue University part of first industry-led collaborative life sciences research institute in the United States.
Molecular Modelling to Help Create Better, Safer Drugs
How our bodies break down the common drugs ibuprofen, diclofenac and warfarin is the subject of a new study from the University of Bristol.
ATARiS Informatics Platform Hits the Jackpot
ATARiS is one of several tools developed at the Broad Institute to precisely tune in to the signals within noisy datasets.
New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure
Computational Tool Translates Complex Data into 2-Dimensional Images
May allow doctors to track progression of cancer, response to treatment, and risk of relapse.
Agilent Technologies Announces Winner of Fifth Annual Early Career Professor Award
Assistant Professor at Northwestern Recognized for Cancer Diagnostics Research.
Launch of £90m Initiative in Big Data and Drug Discovery at Oxford University
'Big data' to revolutionise healthcare.
HealthLinkNow Integrates SBR Health
HLN and SBR announced HLN has selected SBR’s video call routing and management solution to manage virtual patient-provider visits on HLN’s telemedicine network.
Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines
NIAID-funded investigators develop interactive web applications to share data with peers.
Gifts to Boost University of Chicago as Hub for Biomedical 'Big Data'
Two major gifts will build momentum behind the University of Chicago’s leadership in biomedical computation.
ChemAxon Provides Chemistry Informatics Platform for the European Lead Factory
ChemAxon will provide the core tools to support the pan European initiative.
PREMIER Biosoft and JEOL Enter Agreement
The co-marketing agreement aims to advance research involving marker studies, drug metabolite profiling, lipid and proteomics analysis using MALDI-IMS technology.
The Evolution of the Integrated Platform: Accelrys' One-Two Punch
A look at how Accelrys is delivering an integrated platform of enterprise laboratory solutions.
Agilent and Shimadzu to Exchange Chromatography Instrument Drivers
The standardization will reduce costs, enhance interoperability and broaden customer choice.
Kennedy Krieger Institute and Partek Incorporated Awarded $1.8M NIH Grant
Research partnership aimed at developing computational tools to analyze genomic data from patients with autism spectrum disorder and mental health disorders.
The Evolving Relationship of LIMS and Mobile Devices
An Interview with Abbott's Clive Baron about the new STARLIMS Version 11 and how it will leverage mobile devices.
Agilent Technologies Introduces OpenLAB Data Store for Mass Spectrometry
Networked Solution Provides Compliant Storage of ICP-MS Data.
India Laboratory Information Management System Market Trends 2013
Researchmoz releases report on LIMS market segment status in India
Personalis Selects Clarity LIMS, Citing Quick Deployment as Driver
Clarity LIMS User Base Growing
American Engineering Testing Inc. Implements QESTLab, QESTField and Construction Hive
LIMS implementation expected to improve the efficiency and quality of AET operations by electronically registering samples and entering data in the field.
ChemAxon will provide the core tools to support the pan European initiative.
PREMIER Biosoft and JEOL Enter Agreement
The co-marketing agreement aims to advance research involving marker studies, drug metabolite profiling, lipid and proteomics analysis using MALDI-IMS technology.
The Evolution of the Integrated Platform: Accelrys' One-Two Punch
A look at how Accelrys is delivering an integrated platform of enterprise laboratory solutions.
Agilent and Shimadzu to Exchange Chromatography Instrument Drivers
The standardization will reduce costs, enhance interoperability and broaden customer choice.
Kennedy Krieger Institute and Partek Incorporated Awarded $1.8M NIH Grant
Research partnership aimed at developing computational tools to analyze genomic data from patients with autism spectrum disorder and mental health disorders.
The Evolving Relationship of LIMS and Mobile Devices
An Interview with Abbott's Clive Baron about the new STARLIMS Version 11 and how it will leverage mobile devices.
Agilent Technologies Introduces OpenLAB Data Store for Mass Spectrometry
Networked Solution Provides Compliant Storage of ICP-MS Data.
India Laboratory Information Management System Market Trends 2013
Researchmoz releases report on LIMS market segment status in India
Personalis Selects Clarity LIMS, Citing Quick Deployment as Driver
Clarity LIMS User Base Growing
American Engineering Testing Inc. Implements QESTLab, QESTField and Construction Hive
LIMS implementation expected to improve the efficiency and quality of AET operations by electronically registering samples and entering data in the field.
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Identification and Characterization of Strain Specific Drug Target by Subtractive Genome Analysis of Methicillin Resistance Staphylococcus aureus
University of Karachi
This study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology.
Reaxys Xcelerate – Less Searching. More Discovery
Reed Elsevier
Reaxys Xcelerate is a new premium version of Reaxys. Reaxys is a web based workflow tool for synthetic chemists. It is designed to support the optimization of synthetic processes and offers a valuable resource for accurate & validated experimental reaction & substance data.
Processing and Managing Analytical Data to Extract and Share Knowledge – How Far We’ve Come and Why It’s So Hard?
Advanced Chemistry Development Inc.
This paper discusses the ACD/Spectrus Processor, the new all-in-one analytical data processing and chemical characterization software.
GALAS Modeling Methodology Applications In The Prediction Of Drug Metabolism Related Properties
ACD Labs
Analytical identification of metabolites for a drug candidate is usually a time consuming and low-throughput task and is performed only at the later phases of drug development. Therefore the possibility to predict possible sites of human liver microsomal (HLM) metabolism using in silico techniques would be a very attractive feature for any medicinal chemist.
Effective Use of In-Silico Tools in Lead Optimization
ACD Labs
Of all the challenges facing medicinal chemists in general, one of the most significant must be transforming an active molecule into a viable drug. Lead optimization efforts are guided by a combination of factors, such as potency, ease of synthesis, patentability concerns, specific synthetic constrains of the interaction with the target, as well as the lead’s toxicity and ADME properties.
New Approach for In Silico Genotoxicity Testing of Impurities and Degradants
ACD Labs
This study presents a novel approach to aid this assessment based on probabilistic predictors of mutagenicity in Ames test and binding to Estrogen Receptor, supplemented by a knowledge-based system of structural alerts.
QSAR Model of Regioselectivity of Metabolism in Human Liver Microsomes: Development, Validation, Comparison and Adaptation to Novel Compounds
ACD Labs
Analytical identification of metabolites for a drug candidate is usually a time consuming and low-throughput task which is performed only in late drug development phases. Therefore the ability to predict possible sites of human liver microsomal metabolism using in silico techniques would be highly beneficial for any medicinal chemist.
In silico Identification of Metabolic Soft Spots: Case Study Using ACD/ADME Suite Software
ACD Labs
Metabolic stability, determined in liver microsomes, is one of the primary assays used in early drug discovery. A key factor limiting compound half-life is the cytochrome P450 mediated metabolism. High clearance by these enzymes implies a higher and more frequent dosing as well as poses a risk for individual variations in exposure.
Analytical and Chemical Knowledge Management Software for Drug Metabolism Science
ACD Labs
Characterizing metabolite structures and metabolic pathways is essential to understanding the potential biological implications of compounds in drug discovery.
Analytical and Chemical Knowledge Management Software for Drug Metabolism Science
ACD Labs
Characterizing metabolite structures and metabolic pathways is essential to understanding the potential biological implications of compounds in drug discovery.
University of Karachi
This study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology.
Reaxys Xcelerate – Less Searching. More Discovery
Reed Elsevier
Reaxys Xcelerate is a new premium version of Reaxys. Reaxys is a web based workflow tool for synthetic chemists. It is designed to support the optimization of synthetic processes and offers a valuable resource for accurate & validated experimental reaction & substance data.
Processing and Managing Analytical Data to Extract and Share Knowledge – How Far We’ve Come and Why It’s So Hard?
Advanced Chemistry Development Inc.
This paper discusses the ACD/Spectrus Processor, the new all-in-one analytical data processing and chemical characterization software.
GALAS Modeling Methodology Applications In The Prediction Of Drug Metabolism Related Properties
ACD Labs
Analytical identification of metabolites for a drug candidate is usually a time consuming and low-throughput task and is performed only at the later phases of drug development. Therefore the possibility to predict possible sites of human liver microsomal (HLM) metabolism using in silico techniques would be a very attractive feature for any medicinal chemist.
Effective Use of In-Silico Tools in Lead Optimization
ACD Labs
Of all the challenges facing medicinal chemists in general, one of the most significant must be transforming an active molecule into a viable drug. Lead optimization efforts are guided by a combination of factors, such as potency, ease of synthesis, patentability concerns, specific synthetic constrains of the interaction with the target, as well as the lead’s toxicity and ADME properties.
New Approach for In Silico Genotoxicity Testing of Impurities and Degradants
ACD Labs
This study presents a novel approach to aid this assessment based on probabilistic predictors of mutagenicity in Ames test and binding to Estrogen Receptor, supplemented by a knowledge-based system of structural alerts.
QSAR Model of Regioselectivity of Metabolism in Human Liver Microsomes: Development, Validation, Comparison and Adaptation to Novel Compounds
ACD Labs
Analytical identification of metabolites for a drug candidate is usually a time consuming and low-throughput task which is performed only in late drug development phases. Therefore the ability to predict possible sites of human liver microsomal metabolism using in silico techniques would be highly beneficial for any medicinal chemist.
In silico Identification of Metabolic Soft Spots: Case Study Using ACD/ADME Suite Software
ACD Labs
Metabolic stability, determined in liver microsomes, is one of the primary assays used in early drug discovery. A key factor limiting compound half-life is the cytochrome P450 mediated metabolism. High clearance by these enzymes implies a higher and more frequent dosing as well as poses a risk for individual variations in exposure.
Analytical and Chemical Knowledge Management Software for Drug Metabolism Science
ACD Labs
Characterizing metabolite structures and metabolic pathways is essential to understanding the potential biological implications of compounds in drug discovery.
Analytical and Chemical Knowledge Management Software for Drug Metabolism Science
ACD Labs
Characterizing metabolite structures and metabolic pathways is essential to understanding the potential biological implications of compounds in drug discovery.
Qualitative and Quantitative Characterization of the Metabolome, Lipidome, and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC/MS
Waters Corporation
Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.
TransOmics Informatics Powered by Nonlinear Dynamics
Waters Corporation
This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.
Optimization of the DNA Purification Protocol for the Thermo Scientific KingFisher Flex and BindIt 3.1 Software
Thermo Fisher Scientific
Purpose: Optimal quantity and quality of DNA with the magnetic particle based extraction technology. Method: Thermo Scientific KingFisher Flex magnetic particle processor and BindIt® 3.1 Software. Results: By simple optimization of the nucleic acid extraction protocol it is possible to achieve a great yield of high quality DNA.
Data Acquisition and Analysis of 7-ethoxycoumarin and its Metabolites Using TurboDDS Software in the 500-MS Ion Trap
Agilent Technologies
The ion trap is a powerful tool for metabolism studies, due to the MSn capability for the identification of metabolites and structure elucidation of unknown peaks. The TurboDDS™ software on the Varian 500-MS LC Ion Trap eliminates the need to do multiple runs in order to identify metabolites. Once the expected m/z of a metabolite is entered into the method, the 500-MS will automatically look for this m/z and when found, will immediately trigger an MSn experiment.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation
As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
Waters Corporation
Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.
TransOmics Informatics Powered by Nonlinear Dynamics
Waters Corporation
This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.
Optimization of the DNA Purification Protocol for the Thermo Scientific KingFisher Flex and BindIt 3.1 Software
Thermo Fisher Scientific
Purpose: Optimal quantity and quality of DNA with the magnetic particle based extraction technology. Method: Thermo Scientific KingFisher Flex magnetic particle processor and BindIt® 3.1 Software. Results: By simple optimization of the nucleic acid extraction protocol it is possible to achieve a great yield of high quality DNA.
Data Acquisition and Analysis of 7-ethoxycoumarin and its Metabolites Using TurboDDS Software in the 500-MS Ion Trap
Agilent Technologies
The ion trap is a powerful tool for metabolism studies, due to the MSn capability for the identification of metabolites and structure elucidation of unknown peaks. The TurboDDS™ software on the Varian 500-MS LC Ion Trap eliminates the need to do multiple runs in order to identify metabolites. Once the expected m/z of a metabolite is entered into the method, the 500-MS will automatically look for this m/z and when found, will immediately trigger an MSn experiment.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation
As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
