Interfacing Medicinal Chemistry with Structural BioinformaticsThe observed aaRS-specific stability differences between key riboswitch structural elements could potentially be targeted to effect ligand-specificity in future drug discovery efforts.
National Data Center for Cancer Genome ResearchIn the wake of personalized medicine, scientists at the University of California, Santa Cruz, make progress in the management and analysis of large data sets.
Researchers Turn Big Data Problems into Advanced Biology and Drug DiscoveriesUniversity of Illinois at Chicago and The Genome Analysis Centre in Norwich, UK leverage SGI(R) UV(TM) to accelerate drug discovery and complex problem analysis.
New Pathogen Resource LaunchedPhytoPath to help researchers find ways to combat agricultural pathogens.
Disease Model Curation Improvements at Mouse Genome InformaticsThis paper evaluates the Comparative Toxicogenomics Database (CTD) and discusses its strengths and weaknesses.
Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and AnalysisThis paper provides an overview of the data processing tools available, offering a review of the collection of recent reports on the topic.
Structural Studies of Specific Intermolecular Interactions and Self-Aggregation of Biomolecules and Their Application to Drug DesignThe group of scientists performed structural analyses on biologically important molecules and their complexes with partners, hoping to contribute to molecular design for controlling biologically abnormal functions.
Biogem: an Effective Tool Based Approach for Scaling up Open Source Software Development in BioinformaticsTo help encourage developers to contribute more code, Biogem was created; a Ruby application framework for rapid creation of decentralised, internet published software modules written to lower the barrier to entry.
Recent Advances of Metabolomics in Plant BiotechnologyThis article describes the basic analytical advancements in plant metabolomics and bioinformatics and the application of metabolomics to the biological study of plants.
SRI Speeds Development of Genome-Scale Models of Metabolic NetworksThe new MetaFlux functionality can be used to design drugs against disease-causing bacteria and metabolically engineer bacteria to make chemicals and fuels.
