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Webcasts
Rapid and Sensitive Identification of Host Cell Proteins with SWATH® LC-MS Acquisition
Join Eric Johansen PhD, Senior Scientist at Stemcentrx, to learn how to dramatically increase the speed of acquisition of HCP data.
Multi-site LIMS Harmonization
This webinar will explore the process for capturing current state workflows and projecting future state improvements and harmonization across distributed locations and work groups.

Market Reports
Mobile Technology In The Lab Trends 2015
HTStec Limited

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on the use of mobile technology to monitor and control of lab instruments and automated systems carried out in April 2015.
The Global Bioinformatics Market: Market size, forecasts and company profiles
Business Insights

This report provides analysis of bioinformatics market over three major segments, namely tools, content/database and service. It further analyzes each macro market with respect to sub segments from the market prospective. It also gives a qualitative and quantitative view of the bioinformatics market over major geographical regions.
Scientific News
How the Brain Recognizes Faces
Machine-learning system spontaneously reproduces aspects of human neurology.
Improving Drug Production with Computer Model
A model has been developed that can be used to improve and accelerate the production of biotherapeutics, cancer drugs, and vaccines.
Accelerating the Detection of Foodborne Bacterial Outbreaks
The speed of diagnosis of foodborne bacterial outbreaks could be improved by a new technique developed by researchers at the Georgia Institute of Technology.
Largest Resource of Protein-Protein Interactions
Researchers have developed the largest ever database of protein-protein interactions.
NVIDIA Awards $400k to Trailblazers in Cancer Research
NVIDIA Foundation furthers research that could lead to new and more targeted treatments with investments.
Computers Learn to Recognize Molecules That Can Enter Cells
Researchers discover peptides with antimicrobial properties, but also that many known human proteins also had this ability.
Big Data for Infectious Disease Surveillance
NIH-led effort examines use of big data from health records and other digital sources for uses in infectious disease surveillance.
Clinical Screening Test for Gut Health Developed
uBiome has created an entirely new approach to support the clinical diagnosis of gut health conditions.
Computational Tool May Speed Drug Discovery
Scientists are able to see beyond static images of proteins with the help of a new computational tool.
Scientists Develop a Novel Method to Benchmark and Improve the Performance of Protein Measurement Techniques
A wide range of laboratories around the world are benefiting from this work, which enables researchers to analyze or compare the results of quantitative proteomics assays in a standardized way.
Business News
Courtagen, Certainty Health Partner
The partnership will support value-based care, connecting physicians, and improving patient care delivery while reducing health care costs.
Parker Institute, CRI Announces Collaboration on Cancer Neoantigens
This new collaboration, the Tumor neoantigEn SeLection Alliance, includes 30 of the world’s leading cancer neoantigen research groups from both academia and industry.
Aridhia Announces New Deal for RSRCH-Health Service in Netherlands
RSRCH-Health was first established in early 2016 to deliver a digital research environment to Radboudumc Nijmegen in a three-year deal, making it the first University Medical Centre in the Netherlands to offer a digital platform to all research teams across the institution.
Edico Genome, Amazon Web Services Partner
Partnership aims to achieve real-time genomic analysis, provide scalable and secure cloud-based platform.
TSI, DrFirst Collaborate
Collaboration aims to provide PGx-based e-prescribing and medication management.
Improving the Speed and Cost-Efficiency of Drug Discovery
Optibrium and MolPort collaborate, combining MolPort’s 6.3 Million HTS Compounds with StarDrop’s data analysis and compound design capabilities.
Agilent Awards Influential Clinical Genomics Researcher
Dr. Peter Robinson recognized for contributions to clinical genomics and computational biology.
Recursion Raises Additional Funding for Drug Discovery
Recursion Pharmaceuticals announced the close of an additional $2.15M in funding for drug discovery.
sbv IMPROVER Datathon
New approach to connecting data to analytics stimulates multi-disciplinary collaboration and innovation at first sbv IMPROVER Datathon.
Broad Institute, Intel Sign $25M Deal for Genomic Data Analysis
In the age of big data, efficient, comprehensive analysis has become the next key challenge to tackle.

Events
2nd Annual IDMP Update Forum
06 Dec 2016
2nd Annual IDMP Update Forum ...
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Computational Drug Development
13 Dec 2016
Computational Drug Development ...
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IoT Tech Expo Europe
23 Jan 2017
IoT Tech Expo Europe ...
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The 2017 Sports Science Summit
24 Jan 2017
The 2017 Sports Science Summit ...
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ePosters
Building and deploying digital pathology infrastructure for a heterogeneous user base
Faculty of Medicine, Vrije Universiteit Brussel; University Hospital Brussels (UZ Brussel):

Too often, image analysis and data/image mining projects remain stuck in
microenvironments because they are limited by vendorspecific
solutions that neither scale nor interact with material from other departments or institutions. Successful rollout of digital histopathology therefore requires more than a whole slide scanner. At Brussels Free
University (VUB), we wanted to provide a core digital pathology infrastructure that can support a range of different use cases.
The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry
GE Healthcare Dharmacon, Inc.

Dharmacon has previously developed a novel RNA synthesis chemistry making RNA synthesis as reliable, accessible and of comparable quality as routinely observed in DNA synthesis.
Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
Deep Phenotyping - Harnessing Data Richness for Unsupervised High-Content Analysis
Institute of high performance Computing, Astar

Recognising the key challenges, we develop an end-to-end computational framework for HCA dubbed “Deep Phenotyping” that perform unsupervised analysis to leverage on the data richness for the discovery of unknown sub-phenotypes with minimal labeling cost.
The Case for CASE: Computer-Assisted Structure Elucidation
ACD/Labs

Modern CASE systems such as Structure Elucidator Suite provide the necessary capability to accurately elucidate a novel chemical structure for complex molecules based on readily available NMR data sets. This allows organizations to avoid expensive, labor-intensive, and time-consuming synthetic efforts.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Addressing False Positive Variants Arising from Pseudogenes
1National Heart and Lung Institute, Imperial College, London, UK, 2NIHR Cardiovascular BRU, Royal Brompton and Harefield NHS Trust, London, UK, 3Royal Brompton and Har

Clinical genetic testing has been transformed in recent years by the introduction of Next-Generation Sequencing (NGS).
PredRet: Prediction of Retention Time by Direct Mapping between Multiple Chromatographic Systems
Department of Food Quality and Nutrition, Research and Innovation Centre, Fondazione Edmund Mach, San Michele all’Adige (TN), Italy.; Department of Stress and Developmental Biology, Leibniz Institute

Retention time (RT) information is under-utilized in LC-MS based metabolomics and sharing of RTs between systems is not currently possible. PredRet is a new system that allows highly accurate mapping and prediction of RTs between LC systems.
Building a digital pathology ecosystem for education and research
Department of Pathology, Faculty of Medicine, Vrije Universiteit Brussel; Department of Pathology, University Hospital Brussels

We wanted to build a core digital pathology infrastructure to support different use cases. Various images platforms needed to be accessible through a single access point, and support different user profiles.
Predicting Regioselectivityand Labilityof Cytochrome P450 Metabolism using Quantum Mechanical Simulations
Optibrium

Predicting Regioselectivity and Lability of Cytochrome P450 Metabolism using Quantum Mechanical Simulations
Application Notes
Qualitative and Quantitative Characterization of the Metabolome, Lipidome, and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC/MS
Waters Corporation

Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.
TransOmics Informatics Powered by Nonlinear Dynamics
Waters Corporation

This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.
Optimization of the DNA Purification Protocol for the Thermo Scientific KingFisher Flex and BindIt 3.1 Software
Thermo Fisher Scientific

Purpose: Optimal quantity and quality of DNA with the magnetic particle based extraction technology. Method: Thermo Scientific KingFisher Flex magnetic particle processor and BindIt® 3.1 Software. Results: By simple optimization of the nucleic acid extraction protocol it is possible to achieve a great yield of high quality DNA.
Data Acquisition and Analysis of 7-ethoxycoumarin and its Metabolites Using TurboDDS Software in the 500-MS Ion Trap
Agilent Technologies

The ion trap is a powerful tool for metabolism studies, due to the MSn capability for the identification of metabolites and structure elucidation of unknown peaks. The TurboDDS™ software on the Varian 500-MS LC Ion Trap eliminates the need to do multiple runs in order to identify metabolites. Once the expected m/z of a metabolite is entered into the method, the 500-MS will automatically look for this m/z and when found, will immediately trigger an MSn experiment.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation

As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
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