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Tuesday, September 16, 2014
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Recent Advancement in Mendelian Genomics...Lessons Learned from Implementing a Nati...ALFA21 LIMS VIDEO PRESENTATION...

Featured Products
Featured Product - Mosaic Software
Mosaic Software
Featured Product - RealTime StatMiner® – qPCR Data Analysis Software
RealTime StatMiner® – qPCR Data Analysis Software

Webcasts
A High Content Imaging Platform to Study Spatio-temporal Signaling Networks during Neuronal Differentiation
Olivier Pertz, University of Basel, speaking at High Content Analysis 2014
Management of Genomic Big Data in a Country-wide Collaborative Initiative for Rare Disease Gene Finding.
Joaquin Dopazo, Centro De Investigacion Principe Felipe, speaking at Advances in NSG & Big Data 2014

Market Reports
Gene Expression Analysis Market by Technology, Consumables, Services & Applications - Global Forecast to 2018
MarketsandMarkets

Over the years, the gene expression analysis market, comprising of instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of gene expression applications.
High Throughput Screening (HTS) Market by Technology, Applications, and End Users - Forecast to 2018
MarketsandMarkets

Technological advancements and flourishing outsourcing industry likely to propel the growth of the global high throughput screening market. In this report, the global high throughput screening market has been segmented on the basis of technology, products, applications, end users, and geography.
Security Technologies in Biotechnology
RI Technologies

The report serves as a guide to security technology industry for biotechnology applications, covering more than 350 companies that are engaged in security technology/products and services.
Bioinformatics
RI Technologies

This report gives a market insight into products and services used in the bioinformatics industry. The market is analyzed by product and applications; Database, Software and Hardware form the product categories, finding applications in Genomics, Proteomics, Metabolomics, and other (Drug Discovery, Cheminformatics, and Pharmacogenomics).
Pathways to Efficient Drug Development - Advances in Modeling and Simulation Outcomes to Fuel Pipeline Productivity
GBI Research

The report examines the reasons why the pharmaceutical industry is looking for improvements in efficiency whilst acknowledging that pharmaceutical R&D remains a long and risky process. It looks in detail at precompetitive research and evaluates how the industry is pulling together to research solutions to problems that are common to all companies.
Laboratory Information Management System Market in India 2013
Netscribes

The Laboratory Information Management System (LIMS) forms a niche market segment in India presently. The growing systemization of laboratories will gradually steer forth the market. The simultaneous rapid development of Indian healthcare sector that is seeing rise in number of various types of laboratories will propel the future of LIMS adoption in Indian healthcare sector as well.
Big Data Market in India 2013
Netscribes

The report highlights the current as well as the future big data market scenario in India. The report furnishes explicit details on the crucial aspects of the overall market to provide a holistic view, with the aide of crisp and insightful representation of market data.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
DNA Sequencing 2013: Market Developments, Growth Areas and Opportunities
Biopharm Reports

DNA sequencing is important in all areas of biological research and increasing demand for this technique is driving advances in this field, in the form of next-generation techniques. Today, laboratories use a number of different sequencing methods, however common goals include increasing throughputs and speeds, while reducing costs.
Benchtop Automation Trends 2013
HTStec

This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on small-scale or benchtop automation carried out in January 2013.
Scientific News
Key Mechanism in Energy and Information Storage
Observing how hydrogen is absorbed into individual palladium nanocubes, Stanford materials scientists have detailed a key step in storing energy and information in nanomaterials.
Computer Model Reveals Cancer's Energy Source
Findings focused on the energy-making process in cancer cells known as the Warburg Effect.
Ultra-enriched Silicon Paves the Road to Quantum Computing
Using a relatively straightforward technique, a team of NIST researchers has created what may be the most highly enriched silicon currently being produced.
Identification of Psoriatic Arthritis Mediators in Synovial Fluid
This study represents the most comprehensive proteomic analysis of psoriatic arthritis synovial fluid, to date.
Researchers Use ‘Big Data’ Approach to Map the Relationships Between Human and Animal Diseases
EID2 database used to prevent and tackle disease outbreaks around the globe.
Genetic Pathway for Chronic Kidney Disease Revealed
Findings from the study open the door to early treatment for millions at risk for CKD.
Finding Could Revolutionize Drug Discovery
A study by researchers at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Human Proteome Project Uncovers 193 Proteins Not Known to Exist
The team of international researchers reports the identification of 193 novel proteins that came from regions of the genome not predicted to code for proteins.
Pocket Science: New Mobile Application Enables DNA Analysis On The Go
The application analyses ab1(1) DNA sequencing files, enabling science professionals and amateur enthusiasts to engage in scientific analysis from the convenience of their mobile phones.
Software Could Help Predict and Eliminate Allergens
It’s well known that allergies and asthma are on the rise around the globe, with food allergies in children alone rising 50% from 1997 to 2011.
Business News
DNASTAR Awarded Antibody Engineering Software SBIR Grant
Company receives Phase II SBIR grant award from the National Institutes of Health.
BGI, Imperial and Waters Sign Translational Medicine Agreement
The collaboration brings together three of the leading scientific groups in the field of translational medicine.
Waters Unveils Global Mass Spectrometry Headquarters in the UK’s North West
The Right Honourable George Osborne MP joins Waters CEO Doug Berthiaume to mark the official opening of the Waters Mass Spectrometry Headquarters in Wilmslow.
Sophia Genetics Obtains CE-IVD Mark for Bioinformatics Pipeline
The quality assurance certification represents an important step in raising the standards of routine genetic testing and clinical diagnosis.
Agilent, Shimadzu Release GC Instrument Control for CDS
The instrument control provides customers more freedom of choice when selecting a chromatography data system.
Exploring Innovations in SPR & Combination Screening
Genedata customers will discuss innovations in high content imaging, high throughput screening, compound combination screening, and other related topics at User Group Meetings.
QIAGEN, BGI Tech Database Agreement
BGI Tech will provide services to the Greater China market with the widely used HGMD literature source.
ATL to Exhibit Data Automation Solutions at 2014 TCEQ Public Drinking Water Conference
LIMS and lab software solutions to be highlighted
GW University Computational Biology Institute Receives Software Donation
The UNIFlow™ software platform, from UNIConnect, will be used for training in laboratory process management methods.
Berry, Illumina Co-Develop NGS System for CFDA Review and Approval
Berry Genomics will use Illumina’s NGS technology to secure Chinese Food and Drug Administration regulatory approval for clinical applications, expanding access to NGS-based tests in China.

Events
Featured Event
17 Sep 2014
Medical Science Liaison Best P ...
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12th Annual Pharma IT Congress
22 Sep 2014
12th Annual Pharma IT Congress ...
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MES & Process Minds 2014
22 Sep 2014
MES & Process Minds 2014 ...
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ePharma West 2014
22 Sep 2014
ePharma West 2014 ...
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ePosters
MS Data Processing With Full Flexibility Of Universal Processing Software
Thermo Fisher Scientific

Liquid Chromatography (LC) in combination with triple quadrupole Mass Spectrometry (MS) is more and more a common analysis technique in routine laboratories. Especially when using MS/MS selected reaction monitoring (SRM) for a large number of components data handling can be a bottle neck. This poster will show MS data processing of pesticides in water samples using an already established chromatography data system which is now also capable of processing large quantities of MS data.
A complete workflow from sample preparation to analysis using SureSelect target enrichment system for Ion Proton semiconductor sequencing
Agilent Technologies

Agilent’s SureSelect Target Enrichment for the Ion Proton Platform provides a comprehensive, efficient, robust, and cost-effective means to sequence subsets of the human genome.

Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
(1)PREMIER Biosoft, Indore, India; (2)PREMIER Biosoft, Palo Alto, U.S.A; (3)AB SCIEX, Darmstadt, Germany; (4)AB SCIEX, Framingham, U.S.A.

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.
Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
(1)PREMIER Biosoft, Indore, India; (2)PREMIER Biosoft, Palo Alto, U.S.A; (3)AB SCIEX, Darmstadt, Germany; (4)AB SCIEX, Framingham, U.S.A.

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.
Coping with BIG DATA Image Formats: Integration of CBF, NeXus and HDF5, A Progress Report
[1] Department of Mathematics and Computer Science, Dowling College, Oakdale, NY 11769 (USA); [2] Diamond Light Source, Harwell Science and Innovation Campus, OX11 0DE (UK); [3] http://wiki.nexusforma

The best of CBF/imgCIF (the Crystallographic Binary File, which has a complete description of the experiment), NeXus (a common data framework for neutron, X-ray and muon science, which gracefully handles large data sets) and HDF5 (Hierarchical Data Format, version 5, the high-performance data format used by NeXus) are being combined for the management of BIG DATA at synchrotrons.
Design of Mixed-Criticality Applications on Distributed Real-Time Systems
Technical University of Denmark

In this thesis, we are interested in mixed-criticality applications (both in the safety and time domains) implemented using heterogeneous processing elements (PE) interconnected using TTEthernet. We address the problem of synthesizing mixed-criticality applications on partitioned architectures, at the PE level and at the communication level.
ChemoSoft: a new chemometric software for non-chemometricians
UMR1145 INRA/AgroParisTech

Professional applications such as those provide by some software editors and free downloadable toolboxes developed for Matlab®, R, Octave or Scilab propose many computation tools. But, to our best knowledge, very few are usable by neophytes or anyone that are not skilled with chemometrics or statistics. ChemoSoft is the first chemometric software designed for non-chemometricians.
Rapid Identification of Microorganisms by Touch Spray and Paper Spray Ambient Ionization
Purdue University

The rapid and accurate identification of microorganisms is necessary in order to improve public health. Molecular-based identification allows for rapid patient treatment and provides more accurate diagnoses, two crucial aspects for successful treatment, yet a great challenge. In this work PS-MS, an existing ambient method, and TS-MS, a newly developed technique, are being utilized in the rapid discrimination of microorganisms (<2 min).
Molecular Dynamics Simulation Study of Pulmonary Surfactant Interacting With Nanoparticles
University of Karachi

MD simulation studies using NAMD of lipid bilayers supported on alpha-quartz (nanoparticles) and kaolinite with explicit water molecules will be presented to understand the physiochemical effects of nanoparticles on pulmonary surfactant.
Identification and Characterization of Strain Specific Drug Target by Subtractive Genome Analysis of Methicillin Resistance Staphylococcus aureus
University of Karachi

This study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology.
Application Notes
Qualitative and Quantitative Characterization of the Metabolome, Lipidome, and Proteome of Human Hepatocytes Stably Transfected with Cytochrome P450 2E1 Using Data Independent LC/MS
Waters Corporation

Drug toxicity is a major reason for the failure of candidate pharmaceuticals during their development. Therefore, it is important to realize the potential for toxicity in a timely fashion. A label-free multi-omics approach has been applied for the analysis of the transfected human hepatocyte cells by implementing LC/HDMSE, providing both qualitative and quantitative information within a single experiment.
TransOmics Informatics Powered by Nonlinear Dynamics
Waters Corporation

This application note introduces the workflow of TransOmics Informatics Software that has been specifically developed for the larger scale analysis of ion mobility MS data from proteomics and metabolomics data sets, comprising technical and biological replicates.
Optimization of the DNA Purification Protocol for the Thermo Scientific KingFisher Flex and BindIt 3.1 Software
Thermo Fisher Scientific

Purpose: Optimal quantity and quality of DNA with the magnetic particle based extraction technology. Method: Thermo Scientific KingFisher Flex magnetic particle processor and BindIt® 3.1 Software. Results: By simple optimization of the nucleic acid extraction protocol it is possible to achieve a great yield of high quality DNA.
Data Acquisition and Analysis of 7-ethoxycoumarin and its Metabolites Using TurboDDS Software in the 500-MS Ion Trap
Agilent Technologies

The ion trap is a powerful tool for metabolism studies, due to the MSn capability for the identification of metabolites and structure elucidation of unknown peaks. The TurboDDS™ software on the Varian 500-MS LC Ion Trap eliminates the need to do multiple runs in order to identify metabolites. Once the expected m/z of a metabolite is entered into the method, the 500-MS will automatically look for this m/z and when found, will immediately trigger an MSn experiment.
SDMS Vision Publisher Facilitating Masslynx and Empower Software Data Capture
Waters Corporation

As the volume and complexity of research data continues to grow, the use of an electronic format for laboratory record keeping is the key to simple recording and global communication of critical scientific information.
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