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Ingenuity Systems Delivers Integrated Workflow in Ion Reporter™ Software Suite and Ingenuity Variant Analysis Offerings

Published: Sunday, October 14, 2012
Last Updated: Sunday, October 14, 2012
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Ingenuity and Ion Torrent to offer a promotional solution bundle for exome sequencing by the end of 2012

Ingenuity Systems, a leading provider of information and analysis solutions for life science researchers, has demonstrated the integration of Ingenuity Variant Analysis with Ion Reporter™ Software at Ion World 2012. The combined solutions enable users to get one-click access to Variant Analysis to interpret their variants from all human DNA variation workflows.

Integration includes automated user registration and data transfer, allowing researchers to work with Variant Analysis directly from within Ion Reporter. The interactive filter cascade in Variant Analysis provides a streamlined data analysis workflow to identify and prioritize variants.

"Ingenuity Variant Analysis is a natural extension of our cloud-based Ion Reporter Software," said Mike Lelivelt, Ph.D., Director of Bioinformatics at Life Technologies. "Ion Reporter builds a pipeline to do variant calling, mapping, identification and annotation. Variant Analysis extends that pipeline to help researchers identify, prioritize and report the most biologically interesting causal variants for follow-up."

Ion Reporter Software has been developed to simplify bioinformatics data analysis, annotation, reporting, and archiving of semiconductor sequencing data. Ingenuity Variant Analysis combines analytical tools and integrated content to help researchers rapidly identify and prioritize variants by drilling down to a small, targeted subset of compelling variants based on algorithms powered by the Ingenuity Knowledge Base of millions of findings from the biomedical literature and the researcher's own knowledge of disease biology.

"I've been impressed by the capabilities in Ingenuity Variant Analysis to set and adjust rich filters and test new hypotheses with a simple point and click," said Dr. Christopher E. Mason, Assistant Professor, Weill Cornell Medical College. "Increasing access to the unique content and intuitive user interface makes it easier for researchers to get insights from their data, since it allows you to move from a variant file to a hypothesis in a matter of minutes."

Special bundles - Exome Analysis

Ingenuity and Ion Torrent plan to offer a promotional solution bundle for exome sequencing, including the relevant combination of Ion Torrent reagents, Ion Reporter for data processing, and Ingenuity Variant Analysis for additional data interpretation.  The solution bundle will be available by the end of 2012.

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