Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Bruker Announces New Quantitative Proteomics Capabilities with Skyline Software

Published: Sunday, October 14, 2012
Last Updated: Sunday, October 14, 2012
Bookmark and Share
New version of Skyline Software supports Bruker maXis™ series ultra-high resolution ESI-Qq-TOF mass spectrometers.

Bruker has introduced a new version of Skyline Software, now supporting Bruker maXis™ series ultra-high resolution ESI-Qq-TOF mass spectrometers.

Skyline is a widely used, open source proteomics software platform for building Selected Reaction Monitoring (SRM) / Multiple Reaction Monitoring (MRM) and Full-Scan (MS1 and MS/MS) quantitative methods and analyzing the resulting data. It employs cutting-edge technologies for creating and iteratively refining targeted methods for large-scale proteomics studies.

Recently, Skyline developers have added support for a variety of full-scan chromatography-based quantitative proteomics approaches for QTOF and ion trap instruments. These include: MS1 filtering, targeted MS/MS and data independent acquisition (DIA). This fall, the release of a version of Skyline is planned that will add full support of Bruker ESI-Qq-TOF instruments.

Combining Skyline software with Bruker’s recently introduced complete proteomics solution comprised of the nanoAdvance™ UHPLC, the unique CaptiveSpray™ ion source and Ultra-High-Resolution UHR-TOF maXis™ impact will add new quantitative capabilities to Bruker’s fully integrated proteomics solution. More detailed information about qualitative and quantitative proteomics on maXis impact and quantitative data analyses by Skyline will be presented at the Bruker users’ meeting at the HUPO conference on Monday September 10th. (

Brendan MacLean, Software Project Manager for Skyline at the University of Washington School of Medicine, Department of Genome Sciences, said: “The Bruker team has been great to work with. They have clearly made Skyline integration with their instruments a high priority, and the resulting level of interaction and progress in this joint effort is impressive."

Dr. Michael MacCoss, Professor at the University of Washington, School of Medicine, Department of Genome Sciences, said: “We are really excited to support the analysis of Bruker mass spectrometry data. We have always wanted Skyline to support all LC-MS data and we are thankful for the opportunity to expand our analysis capabilities to include Bruker instrumentation."

Dr. Alexander Harder, Director of Product Management at Bruker Daltonics, commented: “We are very pleased to enable our customers to work with Skyline. Brendan has created a team of very talented developers and with more than 12,500 installations of Skyline. The MacCoss lab has set the gold standard for targeted proteomics. This nicely complements our instruments and bioinformatics platform for proteomics applications."

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Bruker and ImaBiotech Announces Collaboration
Bruker to distribute ImaBiotech's Quantinetix software for quantitative MALDI imaging.
Friday, June 21, 2013
Bruker and SCiLS GmbH Announce an Exclusive Partnership for SCiLS Lab Software for MALDI Imaging
SCiLS Lab is the software developed by SCiLS GmbH which allows the user-friendly statistical analysis of large MALDI imaging datasets
Tuesday, May 21, 2013
Scientific News
Editing of LIMS Data Made Faster and More Efficient in Matrix Gemini
The latest version of the Matrix Gemini LIMS (Laboratory Information Management System) from Autoscribe Informatics now provides faster and more efficient editing of LIMS data by eliminating the need for a second editing screen.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
World’s First Therapeutic Venom Database
Open-source library describes nearly 43,000 effects on the human body.
Mathematical Model Forecasts the Path of Breast Cancer
Chances of survival depend on which organs breast cancer tumors colonize first.
The Secret Behind the Power of Bacterial Sex
Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.
Biomedical Imaging at One-Thousandth the Cost
Mathematical modeling enables $100 depth sensor to approximate the measurements of a $100,000 piece of lab equipment.
University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
On Top of the Flu
Chance for advance warning in search-based tracking method.
TGAC Announces Milestone in Wheat Research
A more complete and accurate wheat genome assembly is being made available to researchers, by The Genome Analysis Centre (TGAC) on 12 November 2015.
Shedding Light on “Dark” Cellular Receptors
UNC and UCSF labs create a new research tool to find homes for two orphan cell-surface receptors, a crucial step toward finding better therapeutics and causes of drug side effects.
Scroll Up
Scroll Down

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos