Corporate Banner
Satellite Banner
Informatics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Bruker Announces New Quantitative Proteomics Capabilities with Skyline Software

Published: Sunday, October 14, 2012
Last Updated: Sunday, October 14, 2012
Bookmark and Share
New version of Skyline Software supports Bruker maXis™ series ultra-high resolution ESI-Qq-TOF mass spectrometers.

Bruker has introduced a new version of Skyline Software, now supporting Bruker maXis™ series ultra-high resolution ESI-Qq-TOF mass spectrometers.

Skyline is a widely used, open source proteomics software platform for building Selected Reaction Monitoring (SRM) / Multiple Reaction Monitoring (MRM) and Full-Scan (MS1 and MS/MS) quantitative methods and analyzing the resulting data. It employs cutting-edge technologies for creating and iteratively refining targeted methods for large-scale proteomics studies.

Recently, Skyline developers have added support for a variety of full-scan chromatography-based quantitative proteomics approaches for QTOF and ion trap instruments. These include: MS1 filtering, targeted MS/MS and data independent acquisition (DIA). This fall, the release of a version of Skyline is planned that will add full support of Bruker ESI-Qq-TOF instruments.

Combining Skyline software with Bruker’s recently introduced complete proteomics solution comprised of the nanoAdvance™ UHPLC, the unique CaptiveSpray™ ion source and Ultra-High-Resolution UHR-TOF maXis™ impact will add new quantitative capabilities to Bruker’s fully integrated proteomics solution. More detailed information about qualitative and quantitative proteomics on maXis impact and quantitative data analyses by Skyline will be presented at the Bruker users’ meeting at the HUPO conference on Monday September 10th. (http://www.bdal.com/navi/meta/events/hupo-2012.html).

Brendan MacLean, Software Project Manager for Skyline at the University of Washington School of Medicine, Department of Genome Sciences, said: “The Bruker team has been great to work with. They have clearly made Skyline integration with their instruments a high priority, and the resulting level of interaction and progress in this joint effort is impressive."

Dr. Michael MacCoss, Professor at the University of Washington, School of Medicine, Department of Genome Sciences, said: “We are really excited to support the analysis of Bruker mass spectrometry data. We have always wanted Skyline to support all LC-MS data and we are thankful for the opportunity to expand our analysis capabilities to include Bruker instrumentation."

Dr. Alexander Harder, Director of Product Management at Bruker Daltonics, commented: “We are very pleased to enable our customers to work with Skyline. Brendan has created a team of very talented developers and with more than 12,500 installations of Skyline. The MacCoss lab has set the gold standard for targeted proteomics. This nicely complements our instruments and bioinformatics platform for proteomics applications."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Bruker and ImaBiotech Announces Collaboration
Bruker to distribute ImaBiotech's Quantinetix software for quantitative MALDI imaging.
Friday, June 21, 2013
Bruker and SCiLS GmbH Announce an Exclusive Partnership for SCiLS Lab Software for MALDI Imaging
SCiLS Lab is the software developed by SCiLS GmbH which allows the user-friendly statistical analysis of large MALDI imaging datasets
Tuesday, May 21, 2013
Scientific News
Advancing Protein Visualization
Cryo-EM methods can determine structures of small proteins bound to potential drug candidates.
Gene Expression Controls Revealed
Researchers have modelled every atom in a key part of the process for switching on genes, revealing a whole new area for potential drug targets.
Making Genetic Data Easier to Search
Scripps team streamlines biomedical research by making genetic data easier to search.
Monovar Drills Down Into Cancer Genome
Rice, MD Anderson develop program to ID mutations in single cancer cells.
It’s Now Easier To Go With The Flow
Rice University tool simplifies comparison of flow cytometry data for laboratories.
Making Precision Medicine a Reality
Researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer’s and rheumatoid arthritis – and identifying new drug targets and therapies.
New Database for Sharing MS Clinical Trial Data
A new database containing nearly 2500 patient records from the placebo arms of nine multiple sclerosis (MS) clinical trials is now available for research by qualified investigators.
‘Precision Prevention’ for Colorectal Cancer
New risk prediction model — not yet ready for clinical use — incorporates genetic, lifestyle and environmental risk factors.
Characterizing Cancerous Genomic Variations
Tested on large tumor genomics database, REVEALER method allows researchers to connect genomics to cell function.
Uncovering Hidden Genomic Alterations that Drive Cancers
Tested on large tumor genomics database, REVEALER method allows researchers to connect genomics to cell function.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!