Corporate Banner
Satellite Banner
Informatics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Genedata Biologics 3.0 Boosts Efficiency Through Standardization

Published: Sunday, February 10, 2013
Last Updated: Saturday, February 09, 2013
Bookmark and Share
Enhanced, integrated biologics platform extends biopharma R&D support - from early library generation to candidate development

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, has announced the release of Genedata Biologics™ 3.0, the latest version of its enterprise solution for biologics R&D. A first-in-class software solution for integrated data management, Genedata Biologics enables R&D organizations to more efficiently discover and develop novel biotherapeutics. Version 3.0 dramatically improves process efficiency with new functionality for standardization of antibody screening, protein engineering, and protein production processes.

Standardization – The Strategic Advantage for Innovative R&D in Biotherapeutics


Workflow and nomenclature standardization are key success factors for large-scale biopharma discovery operations, which consist of specialized groups working in division-of-labor environments across departments and sites, as well as with numerous external partners and CROs. A scalable data management platform shared among all stakeholders and directly interfacing with laboratory automation equipment is required to facilitate the frequent handover and processing of candidate molecules, samples, and testing results.

“Standardization is a strategic advantage in today’s biopharma R&D. The new version of Genedata Biologics provides a complete view on all biologics candidates and their history,” said Dr. Othmar Pfannes, CEO of Genedata. “The standardization of these views and the underlying automated data processing minimizes duplication of work, eliminates error-prone manual activities, and provides extremely valuable transparency across an organization for efficient decision making. Our insight into standard processes and best practices has driven the development of Genedata Biologics, which is becoming the data management platform of choice for innovative biologics R&D organizations.”

Genedata Biologics V 3.0 – Highlights


Data Management & Access Control Framework: New user group infrastructure provides a fine-granular mechanism to control access to sensitive data in a collaborative environment. The system now supports cross-departmental and external data exchange with CROs and CMOs, as well as technology transfers among research partners, which is of vital importance in IP-critical environments.

Flexible Reporting Engine: New framework for generating customized reports for scientists, project managers, technicians, and management. Easily generated reports can now be tagged for keywords and relationship (e.g. reporting all cell lines stably expressing Fab-Fvs), research stage and success of results (e.g. portfolio of leads across different screening efforts), or grouped with data, e.g. Protein Expression Batches along with expression levels, vector information (i.e. signal peptides, promoters), or antibody germline sequence information (i.e. IGHV1-24). Typical examples also include KPIs (e.g. real-time overview of the number of candidates successfully expressed and purified, with a monthly break-down), and dashboards for facilitating decision support.

Extended Molecule Processing Support: Enhanced functionalities to register, process, and visualize specific molecule types such as scFv and other antibody- and non-antibody molecules.
High-throughput Antibody Reformatting: Extended support of bulk reformatting from Fab-to-IgG and similar workflows; new reporting and statistics of recovered versus unrecovered clones using a parental Hit List, which enables straightforward antibody clone recovery; systematic handling of incomplete sequences; fully integrated re-streaking support.

Bulk Processing of Protein Production Samples: Support of fully automated protein expression and purification equipment and processes (e.g. automated transient transfection robots in 24-tube racks). Bulk create and edit from native Excel files, in addition to file-based uploads; protein purification batches, as well as assays and analytics data for expression constructs, cell lines, protein expression batches.

Extended Antigen Management: In-house produced antigens and externally-sourced antigen materials; different types of antigens (including cell lines, recombinant versions); integrated material management and availability tracking.

Dedicated Handling of Externally-sourced Materials: Processing and registration logic for externally sourced antibody molecules (e.g. reference compounds) or protein tools. Specific logic for registration and processing of incomplete information (e.g. lack of sequence information).

Expansion of Admin UIs: Facilitates data and configuration maintenance tasks enabling application administrators to easily introduce new controlled vocabularies, sequence motifs for automatic sequence annotations, among others.

Name Generator API: Construct a molecule or sample name by customer-defined rules such as applicable molecules, samples, or for other entities (e.g. for plate name generation). Additional APIs for external registration of actual product protein and protein purification batches for registration in corporate compound registration systems, and others.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Boehringer Ingelheim Chooses Genedata Selector for Cell Line Development and Cell Culture Optimization
Company has announced that the leading pharma company to implement Genedata Selector as its global cell line and genome knowledge management platform.
Thursday, March 10, 2016
Genedata Signs License Agreement with AstraZeneca
Genedata Screener now AstraZeneca’s corporate platform for expediting drug discovery.
Saturday, November 21, 2015
Kymab Implements Genedata Biologics for High-throughput Antibody Discovery
Genedata Biologics™ integrated workflow platform used to increase throughput and automation of Kymab’s transgenic mice-based discovery platforms.
Tuesday, November 17, 2015
Genedata Completes Important Milestone in Collaboration with Bayer Pharma AG
Successful integration of Genedata Profiler™ allows researchers to access, process, analyze and manage petabytes of NGS and other omics data from patients and pre-clinical experiments.
Thursday, September 24, 2015
Merck Serono Chooses Genedata Biologics to Streamline Antibody Discovery Processes
Global deployment of Genedata Biologics across multiple protein therapeutics R&D groups to standardize workflows and improve efficiency.
Thursday, July 23, 2015
Genedata Releases a Breakthrough for Genomic Comparison
Genedata Selector™4.0 provides reference-independent genome sequence comparisons while reducing data processing and analysis time to optimize efficiency and save costs.
Wednesday, July 22, 2015
Genedata Forges Alliance with Intellicyt
Swiss informatics firm Genedata and Intellicyt today announced an alliance to work on cell-based screening in drug discovery.
Thursday, June 18, 2015
Precision Medicine Software Genedata Profiler™ Launched at Bio-IT World
Open, interoperable enterprise platform for patient and compound profiling provides important data management infrastructure for pharma internal R&D processes.
Friday, April 24, 2015
Partner on Innovative Workflow Platform for High-Throughput Cell Line Development
Novel Cell Line Development (CLD) data platform to support the generation and assessment of mammalian production cell lines.
Tuesday, March 17, 2015
Genedata, Bayer Pharma AG Partner on Innovative Workflow Platform for High-Throughput Cell Line Development
Novel Cell Line Development (CLD) data platform to support the generation and assessment of mammalian production cell lines.
Tuesday, March 17, 2015
Genedata Biologics Licensed by Pfizer
Pfizer implements Genedata Biologics to streamline global biopharma R&D processes.
Wednesday, March 04, 2015
Boehringer Ingelheim Selects Genedata Biologics as Antibody Discovery Workflow Platform
Genedata Biologics integrates and streamlines workflows for protein therapeutics R&D groups across multiple Boehringer Ingelheim sites.
Thursday, February 19, 2015
Exploring Innovations in SPR & Combination Screening
Genedata customers will discuss innovations in high content imaging, high throughput screening, compound combination screening, and other related topics at User Group Meetings.
Tuesday, August 26, 2014
GSK Implements Genedata Biologics as Antibody Discovery Platform
Genedata Biologics integrates GlaxoSmithKline's Biopharm Discovery workflows across multiple Biopharm R&D groups and sites
Thursday, June 12, 2014
Genedata Showcases Integrated Analysis & Image Management Solution for Phenotypic Screening
Regardless of instrument or application, Genedata Screener® for High Content Screening enables time-efficient workflow for analysis of high-content experiments
Friday, February 21, 2014
Scientific News
Advancing Protein Visualization
Cryo-EM methods can determine structures of small proteins bound to potential drug candidates.
Gene Expression Controls Revealed
Researchers have modelled every atom in a key part of the process for switching on genes, revealing a whole new area for potential drug targets.
Making Genetic Data Easier to Search
Scripps team streamlines biomedical research by making genetic data easier to search.
Monovar Drills Down Into Cancer Genome
Rice, MD Anderson develop program to ID mutations in single cancer cells.
It’s Now Easier To Go With The Flow
Rice University tool simplifies comparison of flow cytometry data for laboratories.
Making Precision Medicine a Reality
Researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer’s and rheumatoid arthritis – and identifying new drug targets and therapies.
New Database for Sharing MS Clinical Trial Data
A new database containing nearly 2500 patient records from the placebo arms of nine multiple sclerosis (MS) clinical trials is now available for research by qualified investigators.
‘Precision Prevention’ for Colorectal Cancer
New risk prediction model — not yet ready for clinical use — incorporates genetic, lifestyle and environmental risk factors.
Characterizing Cancerous Genomic Variations
Tested on large tumor genomics database, REVEALER method allows researchers to connect genomics to cell function.
Uncovering Hidden Genomic Alterations that Drive Cancers
Tested on large tumor genomics database, REVEALER method allows researchers to connect genomics to cell function.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!