Corporate Banner
Satellite Banner
Informatics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Life Technologies Introduces Two Bioinformatics Offerings for Cancer Researchers

Published: Monday, April 08, 2013
Last Updated: Monday, April 08, 2013
Bookmark and Share
Company has launched Oncomine® Gene Browser and Ion Reporter™ Oncomine® Workflow.

Life Technologies Corporation has announced the introduction of two bioinformatics offerings - Oncomine® Gene Browser and Ion Reporter™ Oncomine® Workflow - that will allow cancer researchers new avenues of access to one of the largest genomics databases available, compiled by the former Compendia Bioscience.

Both products will be featured in Life Technologies' booth (#2222) at the 2013 annual meeting of the American Association for Cancer Research (AACR 2013), April 6 - 10 in Washington, D.C.

Oncomine® Gene Browser
Oncomine® Gene Browser enables cancer researchers to characterize their genes of interest across multiple parameters, including gene expression, DNA copy number and mutation data, from thousands of cancer patients' genetic data (exomes and transcriptomes).

The Oncomine® Gene Browser consists of a simple, dynamic web portal and provides a comprehensive gene summary at a moderate price point.

It is ideal for researchers working with small numbers of genes and enables the survey of individual genes across thousands of de-identified clinical cases and dozens of different cancer types and subtypes.

The new product introduction exemplifies Life Technologies' commitment to offering high-value products in the bioinformatics space across a range of price options and demonstrates the company's ability to serve all customers in the cancer research space, including basic, translational and clinical scientists, as well as those working in the biotech and pharma industry.

"Oncomine® Gene Browser is a new product for the academic and smaller pharma scientist that will enable them to be competitive in research and drug development," said Dan Rhodes, head of medical bioinformatics for Life Technologies.

Rhodes continued, "These investigators will now have access to data that have been collected and curated over the course of a decade, drawing from hundreds of clinical studies and representing millions of dollars worth of experiments, which will allow them to design more focused experiments and make faster progress."

"Oncomine® Gene Browser constitutes a unique solution for scientists working in the drug discovery and companion diagnostics space," said Ronnie Andrews, president of Medical Sciences at Life Technologies.

Andrews continued, "When combined with Life's broad portfolio of instrument systems for cancer research, including our Ion Torrent semiconductor based sequencing system and AmpliSeq Cancer Panels, researchers now have an extremely robust system which will provide markedly enhanced selection criteria to more rapidly advance their research."

Ion Reporter™ Oncomine® Workflow
The Ion Reporter™ Oncomine® Workflow streamlines cancer research by combining its proven Oncomine® platform with Ion Reporter™ Software. It provides access to curated next generation sequencing data from 4,000 matched tumor and normal pairs and is designed to assist with interpreting variants from data obtained on the Ion Torrent™ semi-conductor sequencing platforms from Life Technologies.

Using the Ion Reporter™ Oncomine® workflow with Ion AmpliSeq™ cancer panels, such as the Cancer Hotspot Panel and the Comprehensive Cancer Panel, enables researchers to move from sample to sequence to driver mutations in a day, rather than weeks or months. The Ion Reporter™ Oncomine® Workflow will be available at no charge for an introductory period, making this premier cancer bioinformatics capability accessible to any scientist.

"This is a major advance because cancer sequencing experiments often yield hundreds of variants, among which only a small fraction are true cancer driver mutations," said Dan Rhodes, head of Medical Science Informatics for Life Technologies.

"Previously researchers were faced with cumbersome literature searches or complex bioinformatics approaches to discern drivers from passenger mutations. The thousands of patient tumor samples driving the Oncomine Analysis provide both context and confidence for the Gain of Function or Loss of Function classification. This allows any cancer researcher to immediately identify likely driver mutations in their sample."

Ion Reporter™ Software is a suite of bioinformatics tools that enables users to quickly identify and report on biologically relevant mutations. Ion Reporter™ Software streamlines data analysis by providing simple tools for mapping, calling and annotating variants. The Oncomine® platform is a product of Compendia Bioscience®, a preeminent cancer bioinformatics company, which was purchased by Life Technologies in October 2012.

"Next-generation sequencing of cancer samples identifies many potentially important variants, particularly if matched germline DNA is not sequenced in parallel," said Scott Tomlins, M.D., Ph.D., assistant professor, Department of Pathology, University of Michigan. "The addition of Oncomine® annotations to Ion Reporter™ Software provides the best way to prioritize those mutations that are likely cancer drivers, based on well-curated supporting evidence across cancer types."

Life Technologies acquired Compendia Bioscience® in October 2012. Data compiled by Compendia comprises one of the world's largest and most comprehensive sets of mutation profiles, gene expression data and cellular biomarkers that have been gathered from more than 71,000 cancer patients. Oncomine®, a web-based analytics tool, integrates high-throughput cancer profiling data across a large volume of cancer types that provides researchers with valuable insights into biology, regulation, pathways, drug response, and patient populations.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo Acquisition Approved by Life Technologies Stockholders
Company announced that its stockholders voted to adopt the previously announced merger agreement.
Thursday, August 22, 2013
Life Technologies Announces First Quarter 2013 Results
Revenue increased 2.5% to $963 million.
Friday, May 03, 2013
Life Technologies Acquires Compendia Bioscience
Acquisition of a preeminent cancer bioinformatics company enhance's Life's diagnostic development capabilities across multiple platforms
Sunday, November 11, 2012
Life Technologies introduces Ion AmpliSeq™ Community Panels
Ion AmpliSeq™ Community Panels leverages the expertise of scientific thought leaders and the Ion Community to create gene panels for conditions ranging from cancer to inherited diseases.
Wednesday, November 07, 2012
Life Technologies Acquires Compendia Bioscience
Acquisition expands Life Technologies' ability to drive progress in personalized medicine
Sunday, October 14, 2012
Life Technologies Names Alan Sachs as Head of Global Research and Development
Sachs brings more than 20 years of experience as a research scientist and a leader in developing innovative scientific platforms.
Wednesday, February 01, 2012
Scientific News
Computer Model Could Explain how Simple Molecules Took First Step Toward Life
Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules.
The Mystery of the Instant Noodle Chromosomes
Researchers from the Lomonosov Moscow State University evaluated the benefits of placing the DNA on the principle of spaghetti.
Web App Helps Researchers Explore Cancer Genetics
Brown University computer scientists have developed a new interactive tool to help researchers and clinicians explore the genetic underpinnings of cancer.
An Innovative Algorithm to Decipher How Drugs Work Inside the Body
Researchers at Columbia University Medical Center (CUMC) have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body.
How do Networks Shape the Spread of Disease and Gossip?
A team of mathematicians from Oxford University, University of North Carolina at Chapel Hill, and Rutgers University used a set of mathematical rules to encode how a contagion spreads, and then studied the outcomes of these rules.
AncestryDNA and Calico to Research the Genetics of Human Lifespan
Collaboration will analyze family history and genetics to facilitate development of cutting-edge therapeutics.
Informatics Tool Helps Scientists Prioritize Protein Modification Research
Researchers have developed a new informatics technology that analyzes existing data repositories of protein modifications and 3D protein structures to help scientists identify and target research on "hotspots" most likely to be important for biological function.
Software Differences can Skew Medical Scan Results
Differences in software can significantly skew results of medical scans commonly used in clinical care and research.
AMRI, PerkinElmer to Collaborate on Drug Discovery
Albany Molecular Research (AMRI) and PerkinElmer are collaborating to provide drug discovery infrastructure and services in AMRI's newly launched drug discovery center.
Exploring Living cells
JPK reports the exploration of living cells using nanoscale and single molecule techniques through the application of scanning probe microscopy.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!