Satellite Banner
Informatics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

AB SCIEX Drives Expanded Use of Micro LC for Regulated Bioanalysis

Published: Thursday, July 04, 2013
Last Updated: Thursday, July 04, 2013
Bookmark and Share
Introduction of 21CFR Part 11 module for software control of Eksigent systems to accelerate adoption of micro LC technology.

AB SCIEX has announced the availability of new software and service offerings to simplify and accelerate the integration of micro LC technology into regulated bioanalytical laboratories.

The addition of a new software module supporting 21CFR Part 11 and a new IQ/OQ/PQ service to the Eksigent line of liquid chromatography solutions gives pharmaceutical companies, contract research organizations and other high-throughput laboratories the opportunity to use a validated approach to micro LC for increasing sensitivity and speed while reducing the cost of running a laboratory.

Regulated bioanalytical labs have been looking for ways to improve productivity and efficiency for their ADME and bioanalysis assays but haven’t been able to take advantage of micro LC because of the lack of tools and precedence to integrate it into an existing lab that follows GLP regulations.

The new 21CFR Part 11 module and the new service to qualify the LC system for GLP solve this dilemma for regulated labs by eliminating any doubt that a micro LC solution can be configured to meet required rules and regulations.

For researchers looking for improved sensitivity, efficiency and cost savings, micro LC technology, such as the Eksigent ekspert™ microLC 200 UHPLC system, delivers up to a 4x increase in sensitivity and as much as a 3x increase in throughput while minimizing sample injection volumes. It also can reduce solvent consumption and costs by up to 95%.

Among the regulated labs that are using micro LC is Alturas Analytics Inc., a contract research organization that provides LC/MS-based services to the pharmaceutical and biotech industries.

Scientists at Alturas are using an Eksigent micro LC solution along with AB SCIEX QTRAP technology for an integrated quantitative/qualitative approach.

“By improving the limits of detection with micro LC technology, regulated labs can improve results in bioanalysis,” said Shane Needham, Ph.D., Lab Director, Alturas Analytics, Inc.

Needham continued, “The availability of the 21CFR Part 11 software module is significant because now we can use micro LC for assays that require regulatory compliance, which gives CROs like us a competitive advantage.”

AB SCIEX’s industry-leading, Ekisgent-branded micro LC solutions complement its line of analytical flow LC and nano LC solutions.

The company expanded its chromatography product portfolio in 2012, delivering simplified UHPLC-MS solutions that are tailor-made for a variety of applications.

“AB SCIEX is driving a ‘micro LC for the masses’ philosophy, simplifying the integration of micro LC technology into an existing high-throughput laboratory,” said Ben Moshiri, Ph.D, Director of the Separations Business, AB SCIEX.

Moshiri continued, “End-users can improve productivity, get faster inject-to-inject times, higher sensitivity and reduced costs with the microLC 200 system. We are now enabling the regulated market to take advantage of the power of micro LC in ways that non-regulated markets have known for years.”

The new qualification services for the micro LC and mass spectrometers will provide testing and documentation to verify the proper installation and operation of the system hardware.

Additionally, the LCMS PQ will test and document the overall performance of the micro LC and mass spectrometry instrumentation as a complete system.

The new software module supporting 21CFR Part 11, in conjunction with these qualification services, provides a comprehensive solution that supports customers in achieving a compliant use of these systems for regulated labs.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

SCIEX Announces OneOmics™ Collaborators
Advaita Bioinformatics, Researchers at Yale University and ISB launch applications and libraries that combine next-generation proteomics and next-generation sequencing data in innovative ways.
Thursday, March 19, 2015
AB SCIEX, Illumina Collaborate to Create Multi-omics Cloud-Computing Environment
Integration of SWATH™ Apps with BaseSpace® brings next-generation proteomics and next-generation sequencing together for the first time.
Thursday, October 02, 2014
AB SCIEX and Premier Biosoft Collaborate on Lipidomics Software
PREMIER Biosoft and AB SCIEX collaborate by offering data analysis solutions for lipidomics.
Monday, June 04, 2012
Scientific News
How the Brain Recognizes Faces
Machine-learning system spontaneously reproduces aspects of human neurology.
Improving Drug Production with Computer Model
A model has been developed that can be used to improve and accelerate the production of biotherapeutics, cancer drugs, and vaccines.
Accelerating the Detection of Foodborne Bacterial Outbreaks
The speed of diagnosis of foodborne bacterial outbreaks could be improved by a new technique developed by researchers at the Georgia Institute of Technology.
Largest Resource of Protein-Protein Interactions
Researchers have developed the largest ever database of protein-protein interactions.
NVIDIA Awards $400k to Trailblazers in Cancer Research
NVIDIA Foundation furthers research that could lead to new and more targeted treatments with investments.
Computers Learn to Recognize Molecules That Can Enter Cells
Researchers discover peptides with antimicrobial properties, but also that many known human proteins also had this ability.
Big Data for Infectious Disease Surveillance
NIH-led effort examines use of big data from health records and other digital sources for uses in infectious disease surveillance.
Clinical Screening Test for Gut Health Developed
uBiome has created an entirely new approach to support the clinical diagnosis of gut health conditions.
Computational Tool May Speed Drug Discovery
Scientists are able to see beyond static images of proteins with the help of a new computational tool.
Scientists Develop a Novel Method to Benchmark and Improve the Performance of Protein Measurement Techniques
A wide range of laboratories around the world are benefiting from this work, which enables researchers to analyze or compare the results of quantitative proteomics assays in a standardized way.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!