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Agilent Enhances Dissolution Workstation Software

Published: Friday, August 02, 2013
Last Updated: Friday, August 02, 2013
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Greater instrument control and improved monitoring of pharmaceutical ingredients.

Agilent Technologies Inc. has introduced an enhanced version of its Dissolution Workstation Software, providing better data integration, method change control and instrument monitoring for controlling multiple dissolution systems.

Dissolution is a technique used in the pharmaceutical industry to determine the rate at which pure active pharmaceutical ingredients dissolve.

The software supports laboratory capabilities to build, edit, search, retrieve, execute and archive all dissolution methods and test reports from a single interface. To improve efficiency, the new features allow users to:

• Consolidate and maintain electronic data in one location, with options for exporting information into a laboratory information management system or into business tools such as SAP Crystal Reports or Microsoft Excel.

• Monitor the dissolution apparatus for vibration, environmental impacts and failure investigation assistance when using the optional Instrument Module.

• Comply with the latest enhanced mechanical qualification guidelines, including verifying accessories prior to each test.

• Add an automated system-cleaning cycle to the end of each method, extending the life of dissolution equipment.

“One of the greatest enhancements is the addition of vibration monitoring to the Dissolution Workstation Software,” said Allan Little, marketing director for Agilent’s Dissolution Systems business.

Little continued, “Though there is no standard guidance on vibration measurements, it’s important that laboratories understand the impact vibration can have on their dissolution testing. With baseline values for vibration on the x-, y- and z-axes, dissolution systems as well as their environments may be consistently monitored. This added benefit may be used during early research to develop internal tolerances for specific methods, or as part of a quality-control initiative for well-established methods.”

Dissolution Workstation Software organizes, executes and manages methods and information for all Agilent dissolution equipment, including the Agilent 708-DS, 709-DS, BIO-DIS, Apparatus 7 and dissolution sampling systems.

Continuous audit trails provide reliable traceability of methods and system operation, and reduce the time required to manually document information.

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