Corporate Banner
Satellite Banner
Informatics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Visionary Pharmaceuticals Awarded Phase 1 SBIR Grant

Published: Thursday, August 08, 2013
Last Updated: Thursday, August 08, 2013
Bookmark and Share
Company has been awarded grant to develop TH17 immunomodulators for inflammatory bowel disease.

Visionary Pharmaceuticals, Inc., has announced that the company has obtained a significant Phase 1 Small Business Innovation Research award “Development of RORγt Immunomodulators Targeting the TH17 Axis in IBD”.

The company is using the proceeds to develop novel small molecule retinoic acid related orphan receptor (ROR) modulators targeting TH17 T- lymphocytes in inflammatory bowel disease.

Visionary Pharmaceuticals has created an innovative drug discovery engine utilizing proprietary structure-based drug design technology to focus on nuclear hormone receptors.

The BindingSIGHTs platform encompasses an advanced suite of structural biology and chemical informatics computational tools.

BindingSIGHTs enables sophisticated in silico screening and structure-based drug design for molecular drug targets. With cell assays and deep expertise in nuclear receptor drug discovery Visionary Pharmaceuticals is currently developing several chemically diverse RORγt inverse agonists.

These compounds are potent, selective and demonstrate functional activity to ablate human TH17 differentiation and IL-17 cytokine secretion ex vivo.

“Nuclear hormone receptor modulators account for nearly 15% of all drugs sold in the US with $27 billion in annual sales. In this highly druggable class of targets RORγt inverse agonists represent a potential new source of blockbuster medications for significant unmet medical needs in autoimmune disease. With this grant we can now enable final optimization of our lead series as we move towards selection of an IND candidate.”, said Gordon Alton, Ph.D., President and CEO of Visionary.

Alton continued, “Obtaining this grant, especially under the current NIH budget pressures, reinforces the deep scientific credibility of our organization and rewards us for creating an innovative approach to treating inflammatory bowel disease.”


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Searching Big Data Faster
Theoretical analysis could expand applications of accelerated searching in biology, other fields.
Imaging Software Could Speed Breast Cancer Diagnosis
Technology could improve access to diagnostic services in developing countries.
Data Mining DNA For Polycystic Ovary Syndrome Genes
A new Northwestern Medicine genome-wide association study of PCOS – the first of its kind to focus on women of European ancestry – has provided important new insights into the underlying biology of the disorder.
Firefly Protein Enables Visualization of Roots in Soil
A new imaging tool from a team led by Carnegie’s José Dinneny allows researchers to study the dynamic growth of root systems in soil, and to uncover the molecular signaling pathways that control such growth.
UEA Research Could Help Build Computers From DNA
New research from the University of East Anglia could one day help build computers from DNA.
Viral Comparisons
ORNL team applies genomics expertise to analyze, map virus sequence database.
Preserving Fleeting Digital Information with DNA
A team has demonstrated that DNA they encapsulated can preserve information for at least 2,000 years, and they’re now working on a filing system to make it easier to navigate.
TGAC Leads Development to Diminish Threat to Vietnam’s Most Important Crop
Advanced bioinformatics capabilities for next-generation rice genomics in Vietnam to aid precision breeding.
Mass Extinctions Can Accelerate Evolution
A computer science team at The University of Texas at Austin has found that robots evolve more quickly and efficiently after a virtual mass extinction modeled after real-life disasters such as the one that killed off the dinosaurs.
Furthering Data Analysis of Next-gen Sequencing to Facilitate Research
Researchers at Cincinnati Children's Hospital Medical Center have developed a user-friendly, integrated platform for analyzing the transcriptomic and epigenomic "big data.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!