Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Cerno Bioscience Announces Significant Upgrade of MassWorks Software Product

Published: Saturday, November 23, 2013
Last Updated: Saturday, November 23, 2013
Bookmark and Share
New MassWorks Version 4 adds data support for three high resolution MS systems

Cerno Bioscience has announced a new version of its flagship MassWorks software product. More than any previous improvements and enhancements, the new Version 4 adds DirectRead data support for three high resolution MS systems: Thermo Orbitrap or FT ICR MS, Agilent TOF, and Waters TOF, while expanding unit mass resolution direct support to Agilent MassHunter and Advion CMS. For the first time, MassWorks now enables elemental composition determination in the absence of an observable monoisotope peak or in the presence of larger-than-usual mass errors. In addition, a fully automated calibration feature, AutoCal, is now available for out-of-box accurate mass analysis with GC/MS. Most importantly, the unique ion mixture analysis now handles up to a dozen or more mutually overlapping ions for their accurate quantitation, expanding applications from small molecules to large molecules or biologics and extending its best-in-class formula identification capability to accurate quantitative analysis.

MassWorks won the Most Innovative Product Award at PittCon 2006 for enabling routine formula determination on an otherwise conventional quadrupole MS with up to 100x improvement in mass accuracy through a novel and patented MS calibration algorithm. Important new features have since been added to this innovative software including sCLIPS™ and Spectral Accuracy, a proven companion concept to mass accuracy published in a front cover feature article in Analytical Chemistry ( sCLIPS introduced the concept of Spectral Accuracy to TOF, qTOF, Orbitrap, FT ICR MS, and other high resolution systems and has been shown to eliminate up to 95% of the incorrect formula candidates obtained through accurate mass alone, the details of which can be seen at through a user publication in JASMS.

Dr. Ming Gu, VP for Research at Cerno Bioscience, comments: “With the feature article coverage in a leading journal, MassWorks product has established itself as the most credible and best approach to elemental composition determination, at either unit mass or high resolution, and has won over many hundreds of customers around the world, including a Nobel Prize winning organization. Version 4 represents the most significant upgrade since its debut, which would open new application areas such as hydrogen-deuterium exchange (HDX MS) for protein conformation, accurate quantitation of low level deamination or deamidation impurities in oligo or protein/peptide based biopharmaceuticals, and analysis of the often challenging organometallic compounds.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Agilent to Distribute Cerno's Calibration and Analysis Software with GC/MSD Systems
Novel Program Increases Lab Accuracy and Unknown Compound Identification with Single Quadrupole Instrumentation
Thursday, June 19, 2014
Scientific News
The Secret Behind the Power of Bacterial Sex
Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.
Biomedical Imaging at One-Thousandth the Cost
Mathematical modeling enables $100 depth sensor to approximate the measurements of a $100,000 piece of lab equipment.
University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
On Top of the Flu
Chance for advance warning in search-based tracking method.
TGAC Announces Milestone in Wheat Research
A more complete and accurate wheat genome assembly is being made available to researchers, by The Genome Analysis Centre (TGAC) on 12 November 2015.
Shedding Light on “Dark” Cellular Receptors
UNC and UCSF labs create a new research tool to find homes for two orphan cell-surface receptors, a crucial step toward finding better therapeutics and causes of drug side effects.
Is Allergy the Price We Pay for Our Immunity to Parasites?
New findings help demonstrate the evolutionary basis for allergy.
Questioning the Validity of Forensic DNA Match Statistic
Fifteen years of criminal cases with affected mixture evidence.
Predicting Adverse Drug Reactions with Higher Confidence
A new integrated computational method helps predicting adverse drug reaction—which are often lethal—more reliably than with traditional computing methods.
Healthcare and Life Sciences, Meet the Third Platform of Storage
Current EHR solutions are good for capturing and organizing patient information within a hospital environment, but they are not designed to organize data across the many systems.
Scroll Up
Scroll Down

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos