Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Cerno Bioscience Announces Significant Upgrade of MassWorks Software Product

Published: Saturday, November 23, 2013
Last Updated: Saturday, November 23, 2013
Bookmark and Share
New MassWorks Version 4 adds data support for three high resolution MS systems

Cerno Bioscience has announced a new version of its flagship MassWorks software product. More than any previous improvements and enhancements, the new Version 4 adds DirectRead data support for three high resolution MS systems: Thermo Orbitrap or FT ICR MS, Agilent TOF, and Waters TOF, while expanding unit mass resolution direct support to Agilent MassHunter and Advion CMS. For the first time, MassWorks now enables elemental composition determination in the absence of an observable monoisotope peak or in the presence of larger-than-usual mass errors. In addition, a fully automated calibration feature, AutoCal, is now available for out-of-box accurate mass analysis with GC/MS. Most importantly, the unique ion mixture analysis now handles up to a dozen or more mutually overlapping ions for their accurate quantitation, expanding applications from small molecules to large molecules or biologics and extending its best-in-class formula identification capability to accurate quantitative analysis.

MassWorks won the Most Innovative Product Award at PittCon 2006 for enabling routine formula determination on an otherwise conventional quadrupole MS with up to 100x improvement in mass accuracy through a novel and patented MS calibration algorithm. Important new features have since been added to this innovative software including sCLIPS™ and Spectral Accuracy, a proven companion concept to mass accuracy published in a front cover feature article in Analytical Chemistry ( sCLIPS introduced the concept of Spectral Accuracy to TOF, qTOF, Orbitrap, FT ICR MS, and other high resolution systems and has been shown to eliminate up to 95% of the incorrect formula candidates obtained through accurate mass alone, the details of which can be seen at through a user publication in JASMS.

Dr. Ming Gu, VP for Research at Cerno Bioscience, comments: “With the feature article coverage in a leading journal, MassWorks product has established itself as the most credible and best approach to elemental composition determination, at either unit mass or high resolution, and has won over many hundreds of customers around the world, including a Nobel Prize winning organization. Version 4 represents the most significant upgrade since its debut, which would open new application areas such as hydrogen-deuterium exchange (HDX MS) for protein conformation, accurate quantitation of low level deamination or deamidation impurities in oligo or protein/peptide based biopharmaceuticals, and analysis of the often challenging organometallic compounds.”

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,100+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Agilent to Distribute Cerno's Calibration and Analysis Software with GC/MSD Systems
Novel Program Increases Lab Accuracy and Unknown Compound Identification with Single Quadrupole Instrumentation
Thursday, June 19, 2014
Scientific News
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
Salford Lung Study - The First Real World Clinical Trial
In this podcast, we learn about the Salford Lung Study and its potential to revolutionize the way we assess new drugs and treatments around the world.
Supercomputers Could Improve Cancer Diagnostics
Researchers push the boundaries of cancer research through high-performance computing to map the human immunone.
Systems Medicine – The Future Approach to Diseases
Review give insight into the future of understanding the body and its mechanisms through systems medicine.
Genetic Signature Linked to Cancer Prognosis Identified
The results of the analysis of 8,161 tissue samples could in the future help clinicians decide how best to treat a patient as well as aid the development of new targeted treatments.
Mapping the Human Immune System
Researchers try to harness supercomputers to create the first map of the human immune system.
Microsatellites Linked to Cancer
DNA repeat stretches, called microsatellites, play a greater role in cancer progression and survival that previously thought.
Universal Flu Vaccine Designed by Scientists
An international team of scientists have designed a new generation of universal flu vaccines to protect against future global pandemics that could kill millions.
Faecal Bacteria Linked to Body Fat
Researchers at King’s College London have found a new link between the diversity of bacteria in human poo – known as the human faecal microbiome - and levels of abdominal body fat.
NCI Collaborates with Multiple Myeloma Research Foundation
NCI collaborates with MMRF to incorporate genomic and clinical data into NCI Genomic Data Commons database.
Scroll Up
Scroll Down

SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,100+ scientific videos