Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Aridhia Wins Genomics England Competition

Published: Thursday, May 08, 2014
Last Updated: Wednesday, May 07, 2014
Bookmark and Share
Company wins Genomics England-led SBRI competition to accelerate the adoption of genomics medicine.

Aridhia has won a Genomics England-led Small Business Research Initiative (SBRI) competition to accelerate the development of data management and analytical techniques that will help Genomics England transfer genomic science to genomic medicine within the NHS.

Aridhia’s bid focused on the scale and accuracy of the analytics required to deliver genomic medicine as a routine service by enabling the industrialization of multiple annotation pipelines from different sequence and bio-informatics providers.

If healthcare and research organizations are to deliver on the promise of genomic medicine, considerable developments around the integration, clinical validation and curation of large scale clinical and genomic datasets remain.

The objective of the competition was to discover innovative technologies that would address the requirements of Genomics England’s 100k Genome Project and demonstrate that the solution could provide the NHS with meaningful and actionable data based on patients’ genetic material, with the goal of making this data a routine part of clinical decision making.

The Department of Health is investing up to £10m in this competition, which will be managed by Genomics England Limited and which is expected to run in two phases.

The work will be carried out at the Stratified Medicine Scotland Innovation Centre on AnalytiXagility, the recently launched healthcare and research data science platform developed by Aridhia. The consortium of specialists involved in the project and led by Aridhia includes Fios Genomics, EMC and Pivotal.

David Sibbald, CEO of Aridhia, explains: “Clinical interpretation of sequence data can inform likely disease progression, prognosis and can identify potential response to treatment. Ultimately this could lead to improved treatment success rates and reduce unnecessary side effects. One of the key challenges is the availability of industrial-strength annotation pipelines that can be deployed at scale and integrated effectively with a range of other data associated with patient care and treatment.”

Whole genome sequencing is predominantly a research activity today with genomic annotation currently a limited add-on to diagnostics. The Aridhia-led collaboration aims to develop an innovative set of annotation services technologies, based on its existing AnalytiXagility platform, which will address the challenges of delivering clinically relevant reports, as well as the operational challenges in storing and linking genomic and phenotype data.

The ultimate aim is to identify the best way to present this information to clinicians in an easily interpreted format, giving the NHS access to clinically relevant, actionable information which can be used to directly influence patient care.

The project will run in two phases. Firstly the AnalytiXagility platform will be extended to execute instrumented annotation pipelines, yielding valuable data to improve those services. Scalability tests will be run.

Secondly, the service will be integrated with NHS systems to demonstrate how genomic data can form part of a patient’s electronic health record in a way that can be used in specialist care.

Clinically-led quality control will be built into the process and the outputs. Direct integration of clinical records from the NHS is also expected, along with qualitative measures of user acceptance demonstrated in an NHS setting.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
Friday, November 20, 2015
Aridhia's Data Platform Chosen for Alzheimer's Research Project
Company announces Northern Ireland based Alzheimer's research collaboration to benefit from AnalytiXagility workspace.
Friday, November 06, 2015
Aridhia, Vancis Collaborate
The companies are joining forces to bring combined cloud collaboration services to Netherlands medical research sector.
Thursday, August 06, 2015
Revolutionary Mini-App Technology to Accelerate Clinical Application Development
Aridhia enhances AnalytiXagility data innovation platform with rapid prototyping technology from leading “R” language tools provider RStudio to accelerate translation of precision medicine and biomedical research into clinical practice.
Thursday, July 09, 2015
Aridhia’s Data Science Platform used in €6M EU Project
The company’s data science platform AnalytiXagility has been chosen to underpin a €6 million oral healthcare innovation project.
Thursday, June 18, 2015
New CEO for Aridhia
Aridhia’s Board of Directors has announced the appointment of Chris Roche as Chief Executive Officer (CEO), succeeding co-founder David Sibbald, who takes up the role of Executive Chairman.
Monday, April 27, 2015
Aridhia Sets Its Sights On Us Market With Craneware Partnership
Partnership will enable Aridhia to offer its core services to Craneware’s US client base.
Tuesday, March 10, 2015
Aridhia Secures Place On G-Cloud 6 Framework
Aridhia’s analytics platform and services will be widely accessible to healthcare providers and research collaborations.
Monday, February 02, 2015
Anonymised Clinical Data Key to Understanding Traumatic Brain Injuries
By exploiting big data in a real healthcare setting, it is hoped that clinicians will be able to make treatment decisions earlier.
Thursday, December 11, 2014
Aridhia Appointed to UK Government’s G-Cloud Framework
The latest in collaborative analytical capability now available on-demand to Government and Healthcare Organisations enabling data-driven healthcare.
Tuesday, June 03, 2014
Aridhia Appoints Former EMC Director Chris Roche
The Company announced today the appointment to a newly created post on its executive team of Chief Commercial Officer.
Tuesday, May 27, 2014
Strategic Partnership Signals New Age of Stratified Medicine
Aridhia and Pivotal™ collaborating on revolutionary solutions for chronic disease management.
Thursday, May 02, 2013
Scientific News
The Secret Behind the Power of Bacterial Sex
Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.
Biomedical Imaging at One-Thousandth the Cost
Mathematical modeling enables $100 depth sensor to approximate the measurements of a $100,000 piece of lab equipment.
University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
On Top of the Flu
Chance for advance warning in search-based tracking method.
TGAC Announces Milestone in Wheat Research
A more complete and accurate wheat genome assembly is being made available to researchers, by The Genome Analysis Centre (TGAC) on 12 November 2015.
Shedding Light on “Dark” Cellular Receptors
UNC and UCSF labs create a new research tool to find homes for two orphan cell-surface receptors, a crucial step toward finding better therapeutics and causes of drug side effects.
Is Allergy the Price We Pay for Our Immunity to Parasites?
New findings help demonstrate the evolutionary basis for allergy.
Questioning the Validity of Forensic DNA Match Statistic
Fifteen years of criminal cases with affected mixture evidence.
Predicting Adverse Drug Reactions with Higher Confidence
A new integrated computational method helps predicting adverse drug reaction—which are often lethal—more reliably than with traditional computing methods.
Healthcare and Life Sciences, Meet the Third Platform of Storage
Current EHR solutions are good for capturing and organizing patient information within a hospital environment, but they are not designed to organize data across the many systems.
Scroll Up
Scroll Down

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos