Satellite Banner
Informatics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cresset Announces the Release of Forge V10.3

Published: Tuesday, July 08, 2014
Last Updated: Tuesday, July 08, 2014
Bookmark and Share
Significant new science, visualization and integration for leading ligand-based drug design workbench.

Cresset has announced the release of Forge V10.3. This major new release includes significant enhancements to the science, visualization, and integration of Forge, the computational workbench for ligand-based drug design, including significant enhancements to Activity Miner.

“Activity Miner has been a huge hit since its release as part of Forge last year,” says Dr Tim Cheeseright, Director of Products at Cresset. “Customers have found it invaluable for finding and understanding critical activity cliffs in the SAR landscape. In response to customer requests we have now added selectivity cliffs - the use of multiple activity parameters to look for changes that disproportionately change one activity relative to another.”

“Even though independent tests show that our performance is one of the best, we have still made improvements,” says Dr Mark Mackey, CSO at Cresset. “Forge V10.3 includes improved conformation hunt settings that give significantly fewer, lower energy conformations, enabling you to find the correct alignments even more reliably.”

Major highlights of Forge V10.3 include:
• Find and understand structure-selectivity relationships in Activity Miner
• Perfect the design and activity profile of new molecules using 3D-QSAR models for both primary and secondary activities
• Rapidly analyze large datasets by connecting Forge to cloud or local cluster resources to perform calculations using the Cresset Engine Broker module
• Create detailed pharmacophores from diverse ligands using the integrated FieldTemplater module
• Find new chemical intellectual property using Cresset’s Blaze for ligand-based virtual screening directly from users desktop
• Manipulate complex data within Forge using the new Column Script Editor to automatically modify or calculate molecular properties in the data table.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Cresset Donates to Novartis’ TExts to Sub-Saharan Africa Project
Project donates textbooks to Kenyan university libraries.
Tuesday, September 30, 2014
CloudScientific Appointed as Cresset’s Distributor in China
CloudScientific appointed as distributor of computational chemistry software.
Friday, July 11, 2014
Victrix CMCC Chooses Cresset’s Software for Drug Discovery Consulting Projects
Cresset’s software will help Victrix clients to carry out structure based drug design projects.
Friday, June 28, 2013
Cresset Announces Appointment of David Bardsley as Sales Director
David has extensive knowledge in software and technology solutions.
Monday, August 27, 2012
Cresset Announces new International Sales Team
Cresset has expanded its computational chemistry software sales team in the U.S. and Europe.
Thursday, September 09, 2010
Cresset Announces Appointment of Rob Scoffin as new CEO
Rob replaces Beatrice Leigh, who will now become non-executive Chairman of the Board.
Monday, April 26, 2010
Scientific News
Ancient Eggshell Protein Breaks Through DNA Time Barrier
Fossil proteins from a 3.8million year-old eggshell have been identifed, suggests proteins could give insight into evolutionary tree.
NCI Collaborates with Multiple Myeloma Research Foundation
NCI collaborates with MMRF to incorporate genomic and clinical data into NCI Genomic Data Commons database.
Improving Crop Efficiency with CRISPR
New study of CRISPR-Cas9 technology from Virginia Tech shows potential to improve crop efficiency.
Gene Therapy Technique May Help Prevent Cancer Metastasis
Gene-regulating RNA molecules could help treat early-stage breast cancer tumors before they spread.
Space Research Fighting Cancer
JPL and National Cancer Institute renew Big Data partnership that 'learns' data similarities.
Manipulation of Liquid Crystals Could Help Control Drug-Delivery Process
Computer modeling, real-world testing yields new method.
First Accurate Simulation of a Virus Invading a Cell
For the first time, scientists know what happens to a virus’ shape when it invades a host cell.Understanding how the virus shape specifically changes could lead to more effective anti-viral therapies.
A New Approach for Deciphering Complex Immune Responses
Study seeks to establish the parameters that characterize the immune system of healthy individuals and its natural variability.
Infectious Prion Structure Shines Light on BSE
Prion research useing electron cryomicroscopy technology identified the structure of the infectious prion protein that causes BSE.
Vaccination Strategies Coax HIV-Neutralizing Antibody Production
New approaches to encourage the human immune system to produce HIV-blocking antibodies have been successful in mice.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!