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Reactome - a knowledgebase of human biological pathways
Esther E Schmidt, Michael Caudy, David Croft, Bernard de Bono, Phani V Garapati, Gopal Gopinath, Marc Gillespie, Robin Haw, Bijay Jassal, Steven Jupe, Alexander Kanapin, Shahana Mahajan, Lisa Matthews, Bruce May, Gavin O’Kelly, Imre Vastrik, Guanming Wu, Ewan Birney, Peter D'Eustachio, Lincoln Stein

Reactome is a manually curated knowledgebase, created and peer-reviewed by experts in their field. Its robust data model describes life processes ranging from metabolism to signal transduction and the cell cycle. As of release 28, Reactome contains 3700 human proteins in 3200 reactions. Data is cross-referenced to publicly available web-based informatics resources. Reactome features the SkyPainter tool for analysis of high-throughput datasets, and the Mart query and data retrieval tool.

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Adaptive mixture filtering: an alternative to particle filtering?
Jarad Niemi, Mike West

This poster presents adaptive mixture filtering, an improvement on Gaussian sum filters, as an alternative to particle systems for filtering in state-space models.

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Adaptive mixture filtering: an alternative to particle filtering?
Jarad Niemi, Mike West

This poster presents adaptive mixture filtering, an improvement on Gaussian sum filters, as an alternative to particle systems for filtering in state-space models.

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A Web Interface for Automatic Microarray Analysis
Enrico Glaab, Jonathan M. Garibaldi, Natalio Krasnogor

DNA-Microarray technology provides a diagnostic tool for studying cancer and genetic diseases, allowing the experimenter to identify disease related genes and predict the tumour type for new cell samples. However, the statistical analysis of microarray data is a time-consuming and error-prone process. To address this problem we have developed a web interface for automatic DNA-microarray analysis, ArrayMining.net, which guides the user through the analysis process and performs automatic parameter

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A modular and stochastic approach to the study of gene circuits using P systems
Romero-Campero FJ, Blakes J, Cao H, Camara M, Krasnogor N.

presented at Genomes to Systems Manchester, UK March 17-19 2008

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Formal informatics and machine learning for more principled systems and synthetic biology
Romero-Campero FJ, Blakes J, Camara M, Willams P, Perez-Jimenez MJ, Krasnogor N

presented at European Conference on Synthetic Biology (ESF-UB Conference in Biomedicine), Sant Feliu de Guixols, Spain, 24-29 November 2007.

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A systems analysis of the AHL Quorum Sensing system in Pseudomonas aeruginosa
Romero-Campero FJ, Blakes J, Camara M, Krasnogor N.

presented at Systems Biology (ESF-UB Conference in Biomedicine), Sant Feliu de Guixols, Spain, 12-17 April 2008

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An Integrated Development Environment for Synthetic Biology Models
Blakes J, Romero-Campero FJ, Twycross J, Cao H, Krasnogor N

presented at European Conference on Synthetic Biology (ECSB) II: Design, Programming and Optimisation of Biological Systems (ESF-UB Conference in Biomedicine), Sant Feliu de Guixols, Spain, 29 March - 03 April 2009

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Data Management System for Distributed Virtual Screening
Ting Zhou , Amedeo Caflisch

To manage HTD data effectively and efficiently, we have developed a distributed virtual screening data manage- ment system (DVSDMS) by integrating the open source database MySQL into high throughput docking.

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Showing Results 31 - 40 of 56
Scientific News
Researchers Use ‘Big Data’ Approach to Map the Relationships Between Human and Animal Diseases
EID2 database used to prevent and tackle disease outbreaks around the globe.
Genetic Pathway for Chronic Kidney Disease Revealed
Findings from the study open the door to early treatment for millions at risk for CKD.
Finding Could Revolutionize Drug Discovery
A study by researchers at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Human Proteome Project Uncovers 193 Proteins Not Known to Exist
The team of international researchers reports the identification of 193 novel proteins that came from regions of the genome not predicted to code for proteins.
Pocket Science: New Mobile Application Enables DNA Analysis On The Go
The application analyses ab1(1) DNA sequencing files, enabling science professionals and amateur enthusiasts to engage in scientific analysis from the convenience of their mobile phones.
Software Could Help Predict and Eliminate Allergens
It’s well known that allergies and asthma are on the rise around the globe, with food allergies in children alone rising 50% from 1997 to 2011.
Stanford Bioengineers Create Circuit Board Modeled on the Human Brain
Development offers greater possibilities for advances in robotics and a new way of understanding the brain.
Some Long Non-Coding RNAs Are Conventional After All
Researchers have used ribosome profiling to identify several hundred long non-coding RNAs that may give rise to small peptides.
Taking Immune Cells for a Test Drive
Combining biological experimentation on human white blood cells with advanced computational methods can help explain the functional impact of human genetic variation on immune disease.
Observing Behavior of Single Molecules in Real Time
New technique developed by Stanford scientists allows observation of single molecules of protein or DNA as they bind with other molecules.
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