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Immunological Bioinformatics
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Author(s): Ole Lund, Morten Nielsen, Claus Lundegaard, Can Kesmir and Søren Brunak Hardcover: 310 pages Publisher: The MIT Press (September 1, 2005) Language: English ISBN-10: 0262122804 ISBN-13: 978-0262122801 Product Dimensions: 9.1 x 7.2 x 1 inches Using bioinformatics methods to generate a systems-level view of the immune system; description of the main biological concepts and the new data-driven algorithms. Table of content 1. Immune Systems and Systems Biology 2. Contemporary Challenges to the Immune System 3. Sequence Analysis in Immunology 4. Methods Applied in Immunological Bioinformatics 5. DNA Microarrays in Immunology 6. Prediction of Cytotoxic T Cell (MHC Class I) Epitopes 7. Antigen Processing in the MHC Class I Pathway 8. Prediction of Helper T Cell (MHC Class II) Epitopes 9. Processing of MHC Class II Epitopes 10. B Cell Epitopes 11. Vaccine Design 12. Web-Based Tools for Vaccine Design 13. MHC Polymorphism 14. Predicting Immunogenicity: An Integrative Approach


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