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Protein Nanocages Could Improve Drug Design and Delivery
HHMI scientists have designed and built 10 large protein icosahedra that are similar to viral capsids that carry viral DNA.
Connectome Map More Than Doubles Human Cortex’s Known Regions
Researchers at NIH have developed software that automatically detects the “fingerprint” of each of these areas in an individual’s brain scans.
Virus Inspired Cell Cargo Ships
Virus-inspired container design may lead to cell cargo ships following construction of ten large, two-component, icosahedral protein complexes.
Three-Drug Combinations Counter Antibiotic Resistance
Research shows that combinations of three different antibiotics can treat resistant bacteria, even if they are ineffective independently.
Supercomputing and Drug Discovery
New biotech company uses supercomputer simulations to speed up drug discovery and biotech molecule development.
Identifying Cancer Drug Targets Using 3D-Modelling
Researchers are now able to model genetic mutations manipulation of proteins that can potentially drive cancer.
Human Evolution Driven by Viruses
Study finds surprising percentage of protein adaptions in humans have been driven by viruses.
Earliest Sign of Alzheimer's Development Discovered
Researchers have identified the first physiological signs of late-onset Alzheimer's disease, underlining the importance of computational power in neurology.
Computational Method Offers Significant Boost in Finding New Cancer Targets
MIT and ARIAD Pharmaceuticals team have identified evidence of significant cancer mutations.
Drug Response Predicted by Cancer Cell Lines
Large-scale study could increase success rate of developing personalised cancer treatments.
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Considerations for Maintaining a Validated State of Your Analyst® Software
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SCIEX

Once the system has been validated and put into production it is important to assess the impact on maintaining the validated state of installing updates to your Analyst Software. We recommend that you
read the release notes that accompany each hotfix and determine if there are any updates that apply to your system.

If they do apply to your system, it is important to determine whether any of the updates have regulatory impact. If they do have regulatory impact, it is best to apply them. If they do not have regulatory impact, you will need to weigh the benefit of applying the updates in light of the time and effort that will be required for testing.

It is also worth noting that future hotfixes may require you to install prior hotfixes. It is especially important that updates to auditing and/or electronic signature functionality be applied since they have clear regulatory impact.

The purpose of this white paper is to describe the activities and systems that should be monitored or considered in order to preserve the validated status of Analyst® Software.

Further Information

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