Corporate Banner
Satellite Banner
LIMS & ELNs
Scientific Community
 
Become a Member | Sign in
Home>Events>This Event
  Events - March 2014


Deciphering SAR around aromatics

25 Mar 2014 - 25 Mar 2014 - Webinar



Bookmark and Share


In the medicinal and computational chemists toolbox, the substitution of aromatic groups is a well-used tool to tweak potency and physicochemical properties of drug-like molecules during the optimization process. However, the diversity in positional and functional group substitutions that are synthetically accessible can quickly result in a SAR that is difficult to understand or keep in mind as the project progresses. Small changes in structure can result in large changes in potency (activity cliffs), and the understanding of the causes of activity cliffs is ultimately key to the project success. This webinar will showcase Cresset’s Activity Miner to explore the SAR landscape of a series of compounds involving substituted aromatic moieties, with focus on rapid identification of activity cliffs and how they can be used to better understand the relationship between structure and activity.

Further information
Scientific News
Exploring Living cells
JPK reports the exploration of living cells using nanoscale and single molecule techniques through the application of scanning probe microscopy.
The Perfect Partnership: Research & Industry; Software & Instrumentation. It really starts to come together at ASMS 2015
Collaboration and knowledge-sharing were evident everywhere: on the bus, in the hallways and in the bars. This article aims to capture this theme and share with you some of the fruits of this coming together of science and industry.
Designing New Pain Relief Drugs
Researchers have identified the molecular interactions that allow capsaicin to activate the body’s primary receptor for sensing heat and pain, paving the way for the design of more selective and effective drugs to relieve pain.
Antibody Pries Loose Bacteria’s Grip
Study finds novel method of improving antibody efficacy.
CLAIRE Brings Electron Microscopy to Soft Materials
CLAIRE works by essentially combining the best attributes of optical and scanning electron microscopy into a single imaging platform.
Sample & Analysis Tracking in Oncogenomic Experiments
The study outlines Onco-STS, a web-based laboratory information management system for sample and analysis tracking in oncogenomic experiments.
Pittcon Announces Wide Variety of Short Courses
Courses range from beginner and intermediate to advanced levels.
Ultra-enriched Silicon Paves the Road to Quantum Computing
Using a relatively straightforward technique, a team of NIST researchers has created what may be the most highly enriched silicon currently being produced.
BioClinica and Rutgers University Announce Research Project Results
Scientific Partnership Aims to Expand Automation of Clinical Trial Image Data Analysis
Leading Japanese CRO Standardizes on Thermo Scientific Watson LIMS
JCL Bioassay uses Thermo Scientific Watson LIMS to optimize communication, data management and quality control during U.S. expansion.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!