Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Bruker Announces New Quantitative Proteomics Capabilities with Skyline Software

Published: Sunday, October 14, 2012
Last Updated: Sunday, October 14, 2012
Bookmark and Share
New version of Skyline Software supports Bruker maXis™ series ultra-high resolution ESI-Qq-TOF mass spectrometers.

Bruker has introduced a new version of Skyline Software, now supporting Bruker maXis™ series ultra-high resolution ESI-Qq-TOF mass spectrometers.

Skyline is a widely used, open source proteomics software platform for building Selected Reaction Monitoring (SRM) / Multiple Reaction Monitoring (MRM) and Full-Scan (MS1 and MS/MS) quantitative methods and analyzing the resulting data. It employs cutting-edge technologies for creating and iteratively refining targeted methods for large-scale proteomics studies.

Recently, Skyline developers have added support for a variety of full-scan chromatography-based quantitative proteomics approaches for QTOF and ion trap instruments. These include: MS1 filtering, targeted MS/MS and data independent acquisition (DIA). This fall, the release of a version of Skyline is planned that will add full support of Bruker ESI-Qq-TOF instruments.

Combining Skyline software with Bruker’s recently introduced complete proteomics solution comprised of the nanoAdvance™ UHPLC, the unique CaptiveSpray™ ion source and Ultra-High-Resolution UHR-TOF maXis™ impact will add new quantitative capabilities to Bruker’s fully integrated proteomics solution. More detailed information about qualitative and quantitative proteomics on maXis impact and quantitative data analyses by Skyline will be presented at the Bruker users’ meeting at the HUPO conference on Monday September 10th. (

Brendan MacLean, Software Project Manager for Skyline at the University of Washington School of Medicine, Department of Genome Sciences, said: “The Bruker team has been great to work with. They have clearly made Skyline integration with their instruments a high priority, and the resulting level of interaction and progress in this joint effort is impressive."

Dr. Michael MacCoss, Professor at the University of Washington, School of Medicine, Department of Genome Sciences, said: “We are really excited to support the analysis of Bruker mass spectrometry data. We have always wanted Skyline to support all LC-MS data and we are thankful for the opportunity to expand our analysis capabilities to include Bruker instrumentation."

Dr. Alexander Harder, Director of Product Management at Bruker Daltonics, commented: “We are very pleased to enable our customers to work with Skyline. Brendan has created a team of very talented developers and with more than 12,500 installations of Skyline. The MacCoss lab has set the gold standard for targeted proteomics. This nicely complements our instruments and bioinformatics platform for proteomics applications."

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,700+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Bruker and SCiLS GmbH Announce an Exclusive Partnership for SCiLS Lab Software for MALDI Imaging
SCiLS Lab is the software developed by SCiLS GmbH which allows the user-friendly statistical analysis of large MALDI imaging datasets
Tuesday, May 21, 2013
Scientific News
Breaking Through the Barriers to Lab Innovation
Here we examine the drivers behind the move for greater innovation, the challenges and current trends in laboratory informatics, and the tools that can be used to break these barriers.
Researchers Construct Atomic Model of an Immature Retrovirus
Using molecular modeling and large-scale molecular dynamic simulation, Beckman researchers have constructed an atomic model of an immature retrovirus.
New Mathematics Advances the Frontier of Macromolecular Imaging
Berkeley Lab’s M-TIP solves the reconstruction problem for fluctuation X-ray scattering.
Exploring Living cells
JPK reports the exploration of living cells using nanoscale and single molecule techniques through the application of scanning probe microscopy.
The Perfect Partnership: Research & Industry; Software & Instrumentation. It really starts to come together at ASMS 2015
Collaboration and knowledge-sharing were evident everywhere: on the bus, in the hallways and in the bars. This article aims to capture this theme and share with you some of the fruits of this coming together of science and industry.
Designing New Pain Relief Drugs
Researchers have identified the molecular interactions that allow capsaicin to activate the body’s primary receptor for sensing heat and pain, paving the way for the design of more selective and effective drugs to relieve pain.
Antibody Pries Loose Bacteria’s Grip
Study finds novel method of improving antibody efficacy.
CLAIRE Brings Electron Microscopy to Soft Materials
CLAIRE works by essentially combining the best attributes of optical and scanning electron microscopy into a single imaging platform.
Sample & Analysis Tracking in Oncogenomic Experiments
The study outlines Onco-STS, a web-based laboratory information management system for sample and analysis tracking in oncogenomic experiments.
Pittcon Announces Wide Variety of Short Courses
Courses range from beginner and intermediate to advanced levels.

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,700+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos