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Thursday, February 23, 2012
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Integration of Femtosecond Laser Written...Microfluidic Droplet Testing...Micro Droplets - 5µm to 30µm in diameter...

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Featured Product - ClearCell™ System - isolate, enumerate retrieve wholly intact and viable CTC
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Webcasts
Webcast - Microfluidics Systems for Enhancing Life Science Applications Such as in situ Hybridization and  in vitro Stem Cell Cultures.Microfluidics Systems for Enhancing Life Science Applications Such as in situ Hybridization and in vitro Stem Cell Cultures.
Professor Martin Dufva, Technical University of Denmark, speaking at Lab-on-a-Chip.
Webcast - Microfluidic “Apps” for Commercially Available InstrumentsMicrofluidic “Apps” for Commercially Available Instruments
Professor Roland Zengerle, University of Freiburg, speaking at Lab-on-a-Chip 2011.

Market Reports
Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015)
MarketsandMarkets

The global biochip market is studied by the types and key applications. It was valued at $2.6 billion in 2010 and is expected to reach $5.6 billion by 2015; growing at a CAGR of 16.7%. This growth is attributed to increasing applications in cancer diagnostics and expression profiling, the boom in personalized medicine, and government funding.
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Biochips - Products, Applications, Technologies and End-Use Markets Growth Analysis, 2009-2015
Axis Research Mind

The report reviews the latest biochips market trends with a perceptive attempt to disclose the near-future growth prospects. An in-depth analysis on a geographic basis provides strategic business intelligence for life science sector investments. The study reveals profitable investment strategies for pharmaceutical manufacturers, biotechnology companies, laboratories, Contract Research Organizations (CROs), government organizations and many more in preferred locations.
World Microfluidic Players Database 2011
Yole Développement

Description of more than 620 microfluidic players worldwide. The Microfluidic Players Database 2011 is a unique tool for business and marketing managers which are looking for development or manufacturing partners, customers or research capabilities.
Top 10 Drug Discovery Technologies - Strategic Analysis and Global Forecasts
MarketsandMarkets

The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs. The applications of these technologies in the introduction of drugs have created significant opportunities for market growth. The slow introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.
Nanotechnology in Healthcare: Market outlook for applications, tools and materials, and 40 company profiles
Business Insights

The advent of healthcare nanotechnology has had a vast impact on the fields of drug delivery and diagnostics. Its role in healthcare is very important in terms of eradicating diseases, especially in the treatment of cancer. Advanced technological developments in coatings and implants using nanotechnology are expected to boost the scope of the market in various applications.
Single Cell Analysis 2010: the New Frontier for 'Omics Market Report
Select Biosciences Ltd

Successful conversion of opportunity to profit requires a detailed understanding of this emerging market. Single-Cell Analysis 2010: the New Frontier for ’Omics explains the key technologies, applications, unmet needs and trends. The 128-page report includes a survey of more than 300 participants, interviews with 5 leading experts, analyses of 25 companies and 16 academic programs and a 5-by-7 quantitative market model of technologies and applications.
Multiplexed Diagnostics 2010
Select Biosciences Ltd

The multiplexed diagnostics market has grown rapidly and generated sales of approximately $2.4 billon in 2009, but is now balanced on multiple tipping points.
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Scientific News
Recent Advances in Microfluidic Technologies for Biochemistry and Molecular Biologys
A range of basic biochemical and molecular biological operations have been transferred to chip-based microfluidic formats over the last decade.
Cyclofluidic Announces First Fully Automated Lead Discovery Experiment
Scientists used the company’s proprietary microfluidic system to design, make and screen potential drug molecules active against thrombin, a target associated with stroke.
Deutsch Foundation-Sponsored Work Offers Multi-Pronged Attack on Major Medical Problem
Researchers create a microfluidic “lab on a chip” that uses light to monitor biofilm formation and biofilm response to drugs, detects growth and thickening of biofilms by monitoring translucency.
New Silicon Probe Assists in Disease Diagnostics and Drug Discovery
Scientists have developed a flexible, non-contact microfluidic probe made from silicon that can aid researchers and pathologists to investigate critical tissue samples accurately, reducing the need for large biopsy samples.
Where Nanotechnology and Medicine Meet
University of Alberta oncology professor and team have created a microfluidic chip about the size of a thumbnail that can test for up to 80 different genetic markers of cancer.
OPKO Health Announces Commencement of U.S. Clinical Trial for Point-of-Care Prostate Specific Antigen Test
OPKO intends to submit its application to the U.S. Food and Drug Administration for approval of the assay in 2012.
Vivacta Plans Large Scale Manufacture of Point-of-Care Cartridges
The company plans large scale production of its disposable cartridges to meet commercial demand ahead of establishing strategic relationships with commercial partners.
Artificial Intestine Could Treat Children's Bowel Condition
A tiny 3-D collagen "scaffold" developed in a Cornell lab could prove a lifesaver for those who have lost parts of their intestine.
Veterinarians Hope New Gene Chip will Help Detect, Treat West Nile Virus
A new “gene chip” developed at the University of Florida College of Veterinary Medicine sheds light on brain response in horses infected with West Nile virus and could lead to better ways to diagnose and treat both equines and humans, researchers said.
Roche and Labcyte Integrate Echo and LightCycler Systems to Increase Performance of qPCR-based RNA/DNA Analyses
Companies cooperate around high-speed, miniaturized quantitative PCR (qPCR) to monitor the expression of tens to thousands of genes for therapeutic research.
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Business News
Dolomite and GigaGen Collaborate to Develop Novel Droplet Merging Technology
Development of a novel Droplet Merger Chip for massively parallel single cell genetic analysis.
DNA Electronics CEO to Address Scripps “Future of Genomic Medicine” Conference
Company to present “DNA Transistors and Handheld Sequencing” at key educational conference (La Jolla, California, March 1-2 2012).
Bring a Buddy to ELA 2012
Select Biosciences, organisers of the Second European Lab Automation (ELA) at the Congress Center Hamburg, Germany from 30th-31st May 2012, is pleased to offer a ‘bring a buddy’ discount on conference registration fees.
Nanoink Announces Launch of Contract Services Program for Live Single Cell Assay Work
Service offering expected to advance research programs involved with toxicity assessment, high content screening, and cell-cell communication.
Sagentia Selected by PathoGenetix to Develop Commercial-Scale, Rapid Microbial Detection System
The system is being designed to capitalize on the broad range of potential GSS applications that span microbial genomics research, food and product safety, and clinical infectious disease testing.
Agilent and Monash University Sunway Campus Collaborate
Latest technologies to strengthen university’s investigations into diabetes, cancer, neurobiology and infectious diseases.
Microfluidics Evolution
Lab-on-a-chip devices are creating performance advantages across a wide range of applications and basic research.
Alto Marketing Reappointed as Media Relations Partner for European Laboratory Automation (ELA)
Alto Marketing will be conducting the PR programme and running the on-site press room at ELA for the second consecutive year.
Select Biosciences Gears Up for ELA 2012
Following the success of European Laboratory Automation (ELA) 2011, Select Biosciences has announced that it will be hosting next year’s conference and exhibition at the Congress Centre Hamburg (CCH), Germany, 30 - 31 May 2012.
Gyros Announces Changes to its Management Team
Dr. Jon-Sverre Schanche becomes Chief Technology Officer and Vice President Technical Affairs.
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Events
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22 Oct 2012
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ePosters
Nanoliter Volume Pin Tool Transfers as Measured by a Dual-Dye Absorbance Method
V & P Scientific, Inc.

This poster compares the volumes of sample solutions delivered by an array of stainless steel and hydrophobic-coated pins as measured by a fluorescent-dye approach versus a dual-dye absorbance approach.
SFC Fluidics Microfluidic ePump Technology Ideal for Point of Care Diagnostics
SFC Fluidics LLC

True Point of Care medical devices place unique demand on micropump characteristics. SFC Fluidics ePump is an innovative electrochemical pumping system that is different from other microfluidic pumps.
Magnetohydrodynamic Based Circular Liquid Chromatography On Chip
SFC Fluidics LLC

This poster demonstrates cyclic liquid chromatography on chip and shows how this can be used in other closed loop applications.
Novel Valve Designs in a Completely Sealed Microfluidic System
SFC Fluidics LLC

Two one time use valve strategies have been successfully demonstrated in a completely sealed assay chip. They were also shown to be feasible for on chip reagent storage.
Electrochemical Microfluidic Biosensor for E.coli Detection
INRS-EMT, University of Quebec

Microfluidic electrochemical biosensor based on Loop-mediated Isothermal Amplification (LAMP) was developed for detection and quantification of E.coli. The electrochemical detection was achieved using Hoechst 33258 redox molecule and linear sweep voltametry (LSV). Here, we detect and quantify 48 CFU/ml of bacteria in 35 min in LB media and urine samples. This microfluidic chip has great potential to be used as a point of care diagnostic (POC) device for clinical application.
Aptamer-based protein biochip with a SPAD array time-resolved detection
1-FBK-Fondazione Bruno Kessler, Povo-Trento (Italy) 2-Scuola Superiore Sant’Anna, Pisa (Italy)

In this work a silicon biochip based on a matrix of transparent micro-reactor sites coupled with a linear SPAD (Single-Photon Avalanche Diode) detector array for detecting traces of proteins in biological fluids is presented. A microfluidic layer of PDMS containing a peristaltic pump was implemented. The biofunctional layer for the detection of target proteins is based on a dual-site binding strategy employing DNA aptamers.
Optical Microchip Sensors for Multiplexed Detection of Biological Pathogens
Stratophase

SpectroSens, a multi-channel optical microchip sensor system suitable for rapid, label-free multiplexed detection of a wide range of bio-hazardous agents is presented. Optical chips containing multiple high-precision planar Bragg gratings are exploited as low-cost, robust refractive index sensors.
Low cost direct optical structuring of lab-on-a-chip devices using stamps photopolymer
Universidad Nacional de Ingenieria

In this work the development of microfluidics devices using a simple, fast and low cost fabrication method is shown. The devices were made using a photopolymer designed for making stamps. The obtained results make this concept a convenient technology for configuring compact service areas of specialized microfluidic and detection microstructures compatible with autonomous LOC devices.
On chip micro-extraction and real-time PCR with integrated SPAD optical fluorescence detection for nucleic acid analysis
FBK - CMM

A PDMS lab-on-a-chip for one step DNA isolation and real time-polymerase chain reaction (RT-PCR) has been designed, fabricated, and characterized for point-of-care clinical diagnostics. In addition, a module for on-chip optical detection based on SPAD - Single-Photon Avalanche Diode - detector has also been developed and used to monitor the presence of specific DNA polymorphisms possibly related to genetic diseases.
Cell Preparation in a Microfluidic Mixer
(1) Institute of Microsystems Technology, (2) Institute of Bioprocess and Biosystems Engineering

A microfluidic mixer for the purpose of pulse experiments is designed, fabricated, and characterized. The performance of the micromixer was successfully validated by means of chemical iodemetry. Experiments show that the system is suitable for providing a controlled feeding pulse to a cell population without compromising the viability of eukaryotic cells. The micromixer could be further integrated with other microfluidic components for cell lysis and separation on one chip.
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Application Notes
Overcoming the Challenge of Reliable Multi-way Fluidic Connections
Dolomite

If you are struggling to create fast and reliable microfluidic connections, Multiflux™ may be the solution you are looking for.
Miniaturisation of Gas Chromatography Equipment
Dolomite

Gas Chromatography (GC) is a highly sensitive chemical analysis technique with a broad range of applications. Existing commercial GC systems are generally quite bulky and fragile. Microfluidics enables miniaturisation of the gas chromatography column and low power methods for column heating.
Mitos P-Pump Droplet Monodispersity
Dolomite

The formation of droplets of oil-in-water or water-in-oil has a range of uses in science and industry. Monodispersity, or size consistency, is the key to making droplet microfluidics a powerful tool for conducting accurate and repeatable experiments.
Pathogen Detection
febit biotech gmbh

Whereas most microarray platform providers offer biochips that are very restricted in terms of performing different analysis methods to comprehensively characterize a given sample, a new generation of multiplex assay platforms, such as the Geniom® technology, offers unlimited flexibility and is already applied in various fields of molecular analysis.
Dynamic Detection
febit biotech gmbh

In contrast to many microarray platforms, the Geniom technology provides the user with a unique feature that allows specific measurements and quality control via real-time monitoring on the chip: the dynamic detection of hybridization and amplification. Presenting this novel measuring principle, Geniom enables advanced applications and new approaches.
Enzyme-on-chip
febit biotech gmbh

Geniom® presents a revolutionary combination of PCR and micro-array analyses, superior to any previous approach applied in genomic research. The huge amount of available genomic sequence information of different organisms has opened the door to a post genome era where new challenges arise. One of the most ambitious objectives of this new period is to understand the genome and the products it encodes and how these gene products interact.
microRNA Profiling
febit biotech gmbh

febit’s Geniom Technology addresses the special requirements for the analysis of miRNA expression, its most significant advantage being the extraordinary adaptability to up-to-date information. Keeping the pace with ever changing updates of the miRNA databases as well and easy to handle adjustments of microarray setups, enable modern analyses of miRNA profiles.
Genotyping
febit biotech gmbh

The Geniom® technology for mutational and comparative sequence analysis is based on hybridization of sample DNA to specific probes on the custom array. Use genomic sequence information derived from private or public databases, or select fully validated sequences from our pre-selected probe compositions to determine design and setup of your array.
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