|Hand-held Automated Instrument for Microchip Electrophoresis with Amperometric Detection|
D.F. Pozo-Ayuso, A. Fernández-la-Villa, M. Castaño-Álvarez
Microchips electrophoresis (ME) in combination with electrochemical detection (ED) can bring a new generation of point-of-care (POC) analysis systems in which would be integrated the main steps of an analytical process.
|DC microelectrode array for cell investigation|
Marisa Rio1 , Sharanya Bola2, Salvatore Girardo3, Richard H. Funk2, Gerald Gerlach1
In order to mimic the endogenous dc electric field that cells experience in vivo, a microelectrode array was designed. Preliminary tests showed biocompatibility and promise to render further understanding of the cellular interaction with DC electric fields.
|A multi-resonances valveless micropump with high fluid transportation efficiency|
Ming-Che Hsieh, Min-Fan Huang, and An-Bang Wang
A multi-resonances valveless micropump equipping with inlet/outlet elastic chambers of intendedly-designed stiffness was successfully realized to solve the low efficiency problem. Besides, a theoretical model based on Hydraulic-electrical-Analogy was also proposed to precisely predict its characteristics of dynamic behavior.
|A novel multi-organ microfluidic chip: on the way to the complexity of a living organism|
Timur R Samatov, Svetlana A Tonevitskaya, Natalya Pulkova, Evgeny A Tonevitsky
A novel physiologically relevant multi-organ chip is developed capable of culturing up to six different organotypic models integrated into a single microfluidic circuit.
|ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES|
Ferenc Ender, Diana Weiser, Andras Vitez, Laszlo Poppe
A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.
|Dry-mass sensing for microfluidics|
T. Müller, D. A. White, and T. P. J. Knowles
The dry mass of analyte from microchannels is measured by means of spray-drying on an electromechanical sensor with nanogram sensitivity.
|Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery|
L.D. van Vliet1*, F. Gielen1, A. Sinha2, B.T. Koprowski3, J.B. Edel4, X.Niu5, A.J. deMello3, F. Hollfelder1, & J. Motschman2
To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).
|Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications|
Daniel Czurratis*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**
We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.
|Aptamer-Based Electrochemical Biosensing Platform for Detection of Hormonal Pollutants in Water|
Contreras Jimenez, G.; Eissa, S.; Ng, A.; Zourob, M.; Siaj, M.
A novel detection mechanism based on aptamers has been developed to detect small molecules as hormones, antibiotics, toxins, drugs, etc. For first time, an aptasensor to detect progesterone has been developed.
|New Microarray Slides Capable of Enhancing Fluorescence|
Slides for proteomic microarrays with imbedded nanoparticles that enhance fluoresce by ~ 30-fold via a plasmonic effect. These slides are useful for enhancing fluorescence of protein or peptide microarrays.
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