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Hand-held Automated Instrument for Microchip Electrophoresis with Amperometric Detection
D.F. Pozo-Ayuso, A. Fernández-la-Villa, M. Castaño-Álvarez

Microchips electrophoresis (ME) in combination with electrochemical detection (ED) can bring a new generation of point-of-care (POC) analysis systems in which would be integrated the main steps of an analytical process.

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DC microelectrode array for cell investigation
Marisa Rio1 , Sharanya Bola2, Salvatore Girardo3, Richard H. Funk2, Gerald Gerlach1

In order to mimic the endogenous dc electric field that cells experience in vivo, a microelectrode array was designed. Preliminary tests showed biocompatibility and promise to render further understanding of the cellular interaction with DC electric fields.

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A multi-resonances valveless micropump with high fluid transportation efficiency
Ming-Che Hsieh, Min-Fan Huang, and An-Bang Wang

A multi-resonances valveless micropump equipping with inlet/outlet elastic chambers of intendedly-designed stiffness was successfully realized to solve the low efficiency problem. Besides, a theoretical model based on Hydraulic-electrical-Analogy was also proposed to precisely predict its characteristics of dynamic behavior.

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A novel multi-organ microfluidic chip: on the way to the complexity of a living organism
Timur R Samatov, Svetlana A Tonevitskaya, Natalya Pulkova, Evgeny A Tonevitsky

A novel physiologically relevant multi-organ chip is developed capable of culturing up to six different organotypic models integrated into a single microfluidic circuit.

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ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES
Ferenc Ender, Diana Weiser, Andras Vitez, Laszlo Poppe

A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.

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Dry-mass sensing for microfluidics
T. Müller, D. A. White, and T. P. J. Knowles

The dry mass of analyte from microchannels is measured by means of spray-drying on an electromechanical sensor with nanogram sensitivity.

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Capillary Electrophoresis Coupled with Micro Free Flow Electrophoresis for High Speed Two Dimensional Separations of Biological Samples
Alexander C. Johnson, Michael T. Bowser

We propose using micro free flow electrophoresis (µFFE) as a solution to the under sampling problem.

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Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery
L.D. van Vliet1*, F. Gielen1, A. Sinha2, B.T. Koprowski3, J.B. Edel4, X.Niu5, A.J. deMello3, F. Hollfelder1, & J. Motschman2

To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).

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Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications
Daniel Czurratis*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.

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Aptamer-Based Electrochemical Biosensing Platform for Detection of Hormonal Pollutants in Water
Contreras Jimenez, G.; Eissa, S.; Ng, A.; Zourob, M.; Siaj, M.

A novel detection mechanism based on aptamers has been developed to detect small molecules as hormones, antibiotics, toxins, drugs, etc. For first time, an aptasensor to detect progesterone has been developed.

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Showing Results 1 - 10 of 150
Scientific News
Immunomagnetic Assay On-a-Chip Captures, Analyzes Circulating Tumor Cells
Dartmouth researchers and bioengineers develop novel system to improve cancer treatment.
Mechanically Stimulating Stem Cells
MIT biological engineering graduate student Frances Liu is studying ways to alter mechanical properties of cell environments to produce desired chemical outputs.
Catching And Releasing Tiny Molecules
New technique for sorting biomolecules could lead to efficient clinical diagnostics and chemical purification.
A Single-Cell Breakthrough
UNC School of Medicine scientist Scott Magness and collaborators use their newly developed technology to dissect properties of single stem cells. The advancement will allow researchers to study gastrointestinal disorders and cancers like never before.
Tiny Optical Antennas: A Nano Revolution
Newly developed tiny optical antennas, which function like spotlights at the nanoscale, offer the potential to measure food safety, identify air pollutants and even quickly diagnose and treat deadly diseases, like cancer.
Solving The Mystery Of The Dancing Droplets
Years of research satisfy a graduate student's curiosity about the molecular minuet he observed among drops of ordinary food coloring.
Hearts On A Chip To Aid Drug Screening
UC Berkeley bioengineers have developed a heart-on-a-chip which can be used for drug safety screening.
Lab-On-Paper Invented
New paper-based platform for conducting a wide range of complex medical diagnostics.
Single-Cell, 42-plexed Protein Analysis Achieved with a New Microchip Technology
A novel microdevice capable of detecting 42 unique immune effector proteins has been developed.
Lab-on-a-Chip to Study Single Cells
Scientists at EPFL have developed a new lab-on-a-chip technique to analyze single cells from entire population. The new method, which uses beads and microfluidics can change the way we study mixed populations of cells, such as those of tumors.
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