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Thursday, December 18, 2014
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Development of a Lab-on-a-Chip for the Characterization of Human Cells
Richter, L., Stepper, C., Mak, A., Brückl, H. and Ertl, P.

Cell chips are developed to continuously monitor mammalian cell population dynamics in a non-invasive manner. In the presented work we describe the design, fabrication and characterization of a lab-on-a-chip for quantitative cell analysis.

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Label-free Identification of Microorganisms using a Contact-less Dielectric Microsensor
Ertl, P., Richter, L., Reinthaler, A., Stepper, C., Mak, A., Kast, M., Heer, R. and Brückl, H.

Microfabricated biochips are developed to continuously monitor cell population dynamics in a non-invasive manner. In the presented work we describe the novel combination of contact-less dielectric microsensors and microfluidics to promote biofilm formation for quantitative cell analysis.

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Design, Manufacturing and Test of Disposable Microfluidic System for Blood-Plasma Separation
M. Kersaudy-Kerhoas, F. Amalou, D. Kavanagh, S. Marson, U. M. Attia, P. Summersgill, T. Ryan and M.P.Y. Desmulliez

Prenatal diagnosis to determine the outcome of pregnancies and detect conditions that may affect future pregnancies has risen as a big issue in the broad public. Analysis of fetal genetic material extracted from maternal blood is a smart alternative to invasive prenatal testing.

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EasyBeacons™ - new Probes Ideal for Realtime PCR Detection of Methylation Status of Single CpG Duplets and SNPs
K. Skadhauge, C. Nielsen & U.B. Christensen

The EasyBeacons™ presented here are based on the novel technology Intercalating Nucleic Acid, INA®, linked to a fluorophore and a quencher. INA® is composed of normal DNA nucleotides and Intercalating Pseudo Nucleotides (IPNs). The fact that the EasyBeacons™ are mostly composed of normal DNA nucleotides means that in many respects EasyBeacons™ behave like DNA based probes, allowing use of standard buffers, primers and enzymes and hence reduces the optimisation efforts.

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Novel Fluidics Microbead Trap/Flow Cell Enhances Speed/Sensitivity of Bead-Based Bioassays Up to 5-Fold
RM Ozanich, CJ Bruckner-Lea, JW Grate, MG Warner, BP Dockendorff, KC Antolick, HC Edberg, LH Johnson, AN Easterday

Pacific Northwest National Laboratory (PNNL) has developed a micro/nano particle trap that allows surface-functionalized magnetic or non-magnetic particles to be trapped with subsequent perfusion of sample, reagents and wash solutions, yielding significant (up to 5-fold) improvements in assay speed and sensitivity, while significantly reducing sample matrix effects.

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Utilizing High Speed Photography to Optimize Low Volume Dispensing Conditions
Mary Cornett, Mitch Gordon and Anca Rothe

In this study we use high-speed photography as a feedback mechanism for adjusting the Nanodrop instrument dispense settings to improve the positional dispense accuracy of low volume (nanoliter) drops. These same parameters can be investigated, with various fluid classes, to reduce deleterious effects on dispensing performance such as deflected streams, satellite formation, secondary pulses and drop deformation.

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Detection of Genetically Modified Organisms Using DNA Microarrays
Jaroslava Ovesna, Katerina Demnerova and Lucie Vistejnova

With the increasing production of genetically modified organis ms (GMOs ), the quick detection syst em is required. Microarrays offer a suitable and time saving method. Our aim is to develop DNA microarrays for detection of GMOs.

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Gene Expression in Cold-stressed Barley as Detected by Microarray Analysis
J. Ovesná, B. Svejkovská, L. Kuèera, M. Malý, M. Herbstová and L. Cattivelli

Goal of this work is to find genes in spring and winter barleys that are influenced by cold stress and to analyze their expression profiles during stress. A few of experiments reported influence of temperature on the leaves and crown nodes, that is why we focus our study also on crown nodes by microarray technology.

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A Novel Array- Based Assay for the Detection of Ig G-Mediated Food Intolerance
Andrew Macdonald, Michael J. Walker, Michael S. Walker and Julie G. Reeve

We have developed a microarray based immunoassay to permit both greater food panel diversity and higher throughput testing. The Genarrayt™ 200+ Foods IgG test comprises of glass slides onto which 16 microarrays of over 200 different foods have been printed. Each microarray includes standards for quantitation and positive and negative controls for quality control. Food IgGs are detected by a novel fluorescent dye labelled anti-human IgG conjugate and results are measured using a laser scanner.

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Showing Results 91 - 100 of 137
Scientific News
Predicting Sepsis
Altered white-blood-cell motion in burn patients may warn of infection.
New Advance in Cryopreservation Could Change Management of World Blood Supplies
Engineers have identified a method to rapidly prepare frozen red blood cells for transfusions.
Stanford Engineers Discover How to Record the Forensic History of Chemical Contaminations in Water
An invention called a time capsule is a tiny chemistry lab designed to take a fingerprint of contamination and also disclose when it occurred.
Wallet-Sized Labs The Next Big Thing
RMIT researchers are developing inexpensive, portable toxicology laboratories so small you could fit them in your wallet.
Up-close Look at Cancer on the Move
Microscopic view of metastasis could give insight about how to keep cancer in check.
A Medical Lab For The Home
Fraunhofer FIT demonstrates a mobile wireless system that monitors the health of elderly people in their own homes, using miniature sensors.
Detecting Prostate Cancer With a Microfluidic Device
Innovative device detects prostate cancer, kidney disease on the spot.
Hello? Sweat and a Smartphone Could Become The Hot New Health Screening
A new article highlighting UC research reveals how sweat and microfluidics can pinpoint and help dodge potential health issues for everyone from athletes to preemies.
New 'Lab-on-a-Chip' Could Revolutionize Early Diagnosis of Cancer
Faster result times, reduced costs, minimal sample demands and better sensitivity of analysis.
How Fluid Flow Influences Neuron Growth
A University of Texas at Arlington team exploring how neuron growth can be controlled in the lab and, possibly, in the human body has published a new paper in Nature Scientific Reports on how fluid flow could play a significant role.
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