|Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery|
L.D. van Vliet1*, F. Gielen1, A. Sinha2, B.T. Koprowski3, J.B. Edel4, X.Niu5, A.J. deMello3, F. Hollfelder1, & J. Motschman2
To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).
|Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications|
Daniel Czurratis*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**
We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.
|Aptamer-Based Electrochemical Biosensing Platform for Detection of Hormonal Pollutants in Water|
Contreras Jimenez, G.; Eissa, S.; Ng, A.; Zourob, M.; Siaj, M.
A novel detection mechanism based on aptamers has been developed to detect small molecules as hormones, antibiotics, toxins, drugs, etc. For first time, an aptasensor to detect progesterone has been developed.
|Development of a Microfluidic Device for Sperm Movement|
Shweta Bhagwat (b), Vibha Jayaraj* (b), Priyanka Parte (a), Sameer Jadhav (b)
We show the design of a device for studying sperm chemotaxis and the testing of different chemicals as a source of chemoattractants.
|New Microarray Slides Capable of Enhancing Fluorescence|
Slides for proteomic microarrays with imbedded nanoparticles that enhance fluoresce by ~ 30-fold via a plasmonic effect. These slides are useful for enhancing fluorescence of protein or peptide microarrays.
|A pico-liter semi-automated screening method for morphological identification of microorganisms from environmental samples|
Ms. Charmi Chande, Dr. Ravindra Phadke
An economically feasible microfabrication protocol was developed for fabricating micro features used for bacterial analysis from environmental samples like soil and green sulfur bacteria sample. Organisms were classified in 11 morphotypes by using open source Image analysis software named CMEIAS and the standardized protocol was confirmed by viable count and pure culture study
|Microelectrodes for Microdroplet Motion Based On Electrowetting: A Review on Design|
Nurul Amziah Md Yunus, Noor Faezah Ismail, Seyed Amin Firouzeh, Zurina Zainal Abidin, Nasri Sulaiman and Izhal Abdul Halin.
The technology is growing rapidly whereby the researchers all over the world have discovered the smaller scale of technology. In micro-nanotechnology, the microfluidic manipulation become useful in many field of applications and one of the most advanced method is electrowetting. The observation and review on the design of microelectrode for droplet motion based on electrowetting with different shapes, sizes and fabrication regarding on the different application are hereby reported.
|Real Time Dual-Channel Multiplex SERS Ultradetection|
Sara Abalde-Cela,†,‡ Chris Abell,† Ramón A. Álvarez-Puebla, ?,§ and Luis M. Liz-Marzán‡,?,#
Real time On-line multiplex SERS detection in a microfluidic device.
|Flow Enhancement and Dynamic of Microfluidic Base Biosensor |
Esmail Abdullah Mohammed Basheer, Hayder A.Abdul Bari
The design of new biosesnor base on microfluidic system is presented. The design is consist of two chips, Microchannels chip and electrodes chip. By varying the size and optimizing the microchannels and electrode, the sensitivity of the biosensor will increase.