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Direct On-chip Storage and Release of Liquid Reagents for Diagnostic Lab-on-a-Chip Devices
Daniel Czurratis*, Thomas Brettschneider*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**

We present a direct on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip devices. Reagent release is pressure driven and realized by braking up a barrier film through a deflection of a flexible membrane.

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Polymerized Poly(ethylene glycol) Diacrylate Microfluidic Membrane Valves
Chad I. Rogers, Joseph B. Oxborrow, Long-Fang Tsai, Gregory P. Nordin, and Adam T. Woolley

Polymerized poly(ethylene glycol) diacrylate (poly-PEGDA) was fabricated into pneumatically controlled, non-elastomeric membrane valves as a nonspecific adsorption resistant alternative to polydimethylsiloxane valves. Temporal response, valve closure, and long-term durability of these poly-PEGDA valves were evaluated.

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Polymerized Poly(ethylene glycol) Diacrylate Microfluidic Membrane Valves
Chad I. Rogers, Joseph B. Oxborrow, Long-Fang Tsai, Gregory P. Nordin, and Adam T. Woolley

Polymerized poly(ethylene glycol) diacrylate (poly-PEGDA) was fabricated into pneumatically controlled, non-elastomeric membrane valves as a nonspecific adsorption resistant alternative to polydimethylsiloxane valves. Temporal response, valve closure, and long-term durability of these poly-PEGDA valves were evaluated.

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Polymerized Poly(ethylene glycol) Diacrylate Microfluidic Membrane Valves
Chad I. Rogers, Joseph B. Oxborrow, Long-Fang Tsai, Gregory P. Nordin, and Adam T. Woolley

Polymerized poly(ethylene glycol) diacrylate (poly-PEGDA) was fabricated into pneumatically controlled, non-elastomeric membrane valves as a nonspecific adsorption resistant alternative to polydimethylsiloxane valves. Temporal response, valve closure, and long-term durability of these poly-PEGDA valves were evaluated.

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A Distinctive Analysis of Fluid Flow Behaviour in an AC Electroosmotic Micropump
Nurul Amziah Md Yunus, Farideh Abhari, Mohd Nizar Hamidon, Zurina Zainal Abidin, Izhal Abdul Halin, Gerard H. Markx and Nicolas G. Green

Microfluidic systems are used for chemical and biological analyses, sensing, drug delivery and molecular separation.

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Low-cost “Plug & Play” On-Chip Valve and Pump for Thermoplastic Microfluidics
Mousavi Shaegh Seyed Ali, Wang Zhenfeng, Toh Guek Geok, Soh Yong Chear

Scientists have developed a novel on-chip valving solution for thermoplastic microfluidic devices, which is reliable, easy to implement, and has low-cost fabrication.

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A novel DNA amplification method based on silicon microring resonator for rapid detection of genetic alteration in the point-of care (POC) field of cancers

Nucleic acid testing plays a critical role in molecular diagnosis[1-2]. Due to the low amounts of DNA obtained in clinical samples, the amplification of DNA is an essential step in most NAT methods [3].

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Rapid Concentration of Particles in Microfluidics using AC Electrothermal Effect with Laser Illumination

In this study, the formation of a toroidal microvortex by AC electrothermal (ACET) effect was numerically visualized using COMSOL v4.2a multiphysics software. AC voltage was applied to the two parallel electrodes in a microchannel to generate temperature gradient in the fluids.

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Microfluidic analysis of amino acids using aminoacyl-tRNA synthetase coupled with spectrophotometric detection

Analyses of free amino acids in biological fluids?—?such as urine and plasma?—?can be useful in determining disease status in clinical diagnoses [1]. In the food industry, unique changes in amino acid concentrations are useful markers of freshness, nutrition, and taste.

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Showing Results 31 - 40 of 153
Scientific News
First Liquid Nanolaser Developed
Technology could lead to new way of doing ‘lab on a chip’ medical diagnostics.
Tiny Lab Devices Could Attack Huge Problem of Drug-Resistant Infections
NIH-funded project aims for fast identification and destruction of deadly bacteria.
Detecting Cryptosporidium in China
A recently developed lab-on-a-chip device, which can diagnose the opportunistic parasite in as little as 10 minutes, may help improve treatment in remote, at-risk rural areas.
Detecting Low-Quality Antimalarial Drugs With A Lab-On-Paper
Lab-on-Paper can detect low-quality anitmalarial drugs without expensive equipment.
Measuring Volumes of Key 'Lab on a Chip' Components
NIST found a combination of techniques to effectively measure microfluidic channels, achieving an accuracy of within 5 percent for both a channel's depth and its bottom's width.
Superior Ability To Rapidly Detect Volatile Organic Compounds
Researchers develop a credit-card-sized gas chromatography platform that can analyze volatile compounds within seconds.
Breath Test For Detecting Head And Neck Cancer
A portable device can detect the presence of certain types of cancer in people's breath.
Characterizing the Micro-Mechanical Properties of Soft Materials, Tissues and Cells
Ernst Breel of Optics11 discusses the current problems with characterizing the mechanical properties of soft materials, focusing on how the company's Piuma Nanoindenter can assist researchers.
Using Sound Waves To Detect Rare Cancer Cells
Acoustic device can rapidly isolate circulating tumor cells from patient blood samples.
Immunomagnetic Assay On-a-Chip Captures, Analyzes Circulating Tumor Cells
Dartmouth researchers and bioengineers develop novel system to improve cancer treatment.
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