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Microarray Analysis Using Competitive Hybridization
In this work we explore the effects of wild-type and single nucleotide polymorphism (SNP) target specie concentrations, temperature, and the time of hybridization on sensing specificity in two component systems. A finite element method is used to simulate the diffusion of DNA through a microfluidic chamber to the sensing surface of bound oligonucleotide probes where hybridization of DNA is modeled using the corresponding chemical reaction equation assuming low grafting density.

Date Posted: 01/02/2007 13:06:57
ePosters.net Ref: EP0


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