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Featured Product - BenchTOF-Evolve
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Featured Product - Accelerating GC/MS and LC/MS Sample Preparation
Accelerating GC/MS and LC/MS Sample Preparation

Webcasts
Webcast - A Streamlined Approach for Biotherapeutic CharacterizationA Streamlined Approach for Biotherapeutic Characterization
This presentation will discuss a streamlined solution for collecting and processing data for routine intact mass and peptide workflows.
Webcast - The Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in DiseaseThe Lipidyzer™ Platform: A Revolutionary Tool for Understanding the Role of Lipids in Disease
Join us to learn about the key challenges in lipid analysis and how the Lipidyzer platform can help you overcome them.

Market Reports
Label-Free Binding Analysis Trends 2014
HTStec

This market report summarizes the results of HTStec’s 4th global web-based benchmarking survey on label-free (LF) binding analysis carried out in July 2014. The study was initiated by HTStec as part of its regular (every 2 years) tracking of this life science marketplace. The questionnaire was compiled to address the needs and interests of the LF binding analysis vendor community.
Mass Spectrometry for Clinical Diagnostics Applications 2013 Focus Report
SELECTBIO

This report from SELECTBIO addresses a number of topics including, market segmentation, market landscape, and mass spectrometry products currently on the market as well as in development.
Biomarkers in Late-Stage Clinical Trials: Applications, opportunities and activities of leading players
Business Insights

Biomarkers reduce the attrition rate of late-stage clinical trials by assessing drug potential in terms of efficacy and toxicity at the early stages of clinical development. Thus, biomarkers significantly increase productivity, lower the cost and duration of clinical trials, and help researchers complete the drug development process at a faster pace.
Multiplexed Diagnostics 2010
Select Biosciences Ltd

The multiplexed diagnostics market has grown rapidly and generated sales of approximately $2.4 billon in 2009, but is now balanced on multiple tipping points.
Genomics, Proteomics and Metabolomics in Diagnostics: Market landscape, innovative technologies and future outlook
Business Insights

There has been a significant transition in the diagnostic techniques created with increasing technological innovations. In the future, the focus will be on genetic study and disease predisposition, which will test patients' probability of acquiring a disease or a disorder, enabling precautionary steps.
Scientific News
Featured Article
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.

Gene Deletion Reveals Cell Secrets
Researchers have deleted 174 genes in yeast to analyse the effect of individual gene deletion.
Peer Reviewed Study Demonstrates Mass Spec Technique
The peer reviewed study demonstrates MS workflow, TMTCalibrator workflow, which dramatically enhances detection of key early stage Alzheimer’s biomarkers.
Impact of Emerging Contaminants in Our Water Supply
Emerging contaminants, any synthetic or naturally occurring chemical not commonly monitored in the environment, in our water supply are becoming of increasing concern due to their potential ecological and/or human health effects.
Collaboration to Develop Cannabis Testing Standards
SCIEX workflow solution enables cannabis labs to ensure product safety with robust, cost-effective analytical methods to facilitate routine testing.
Antibiotic Resistance Genes in Indoor Dust
Genetic analyisis of dust samples discovered antimicrobial chemicals and antibiotic-resistance genes.
Sharks Contain High Levels of Neurotoxins Linked to Alzheimer’s
Research team suggests restricting shark consumption to protect human health as shark fins & meat contain high levels of neurotoxins.
Peptide Mutants Help Identify Vulnerability in Tumor Cells
Researchers can detect mutant proteins based on MS data and the results of exome sequencing.
Diverse Fungi Secrete Similar Suite of Decomposition Enzymes
A recent study reveals different fungal species secrete a rich set of enzymes that share similar functions, despite species-specific differences in the amino acid sequences of these enzymes.
Misfiring Drugs Hit the Wrong Targets
Anti-HIV protein inhibitor drugs can bind to the wrong protein, causing unwanted side effects.
Business News
Bruker, 3M Expand License
Bruker has expanded its license agreement with 3M for the processing of formalin fixed parafin embedded (FFPE) tissue sections.
Analytik Jena and Fresenius University are Set Up a Joint Application Center
With the new application center, Company is responding to growing demand for consulting, seminar, and training opportunities in the Frankfurt am Main economic region.
Pittcon Announces 40+ New Classes in 2017 Short Course Program
The courses for broad-based application and general lab functions include lab management, quality control, technical writing, statistics, data management, and lab safety.
Owlstone Medical Makes Appointments to Senior Team
Owlstone Medical has announced Chris Hodkinson, Dr Marc van der Schee and Hamilton Scanlon have been appointed in the company.
InSource Launches Clinical Trial Focused on PGx
Physicians' offices invited to become research sites and enroll patients.
SCIEX Works with the Francis Crick Institute and the University of Cambridge
New proteomic study to develop advanced resource for precision medicine research by using Microflow SWATH® Acquisition for HT industrialized proteomics.
Thermo, NIBRT Announce Collaboration
Analytical solutions designed to streamline workflows, quickly generate data for deeper understanding of molecular complexes.
£18m Lab Opens to Discover the Clues to Individuals’ Illnesses
The Centre will identify biomarkers – the molecular clues that indicate the presence of a disease or condition.
Waters Collaborates with Singapore’s Bioprocessing Technology Institute
Organizations partner to enhance the development of analytical methods and glycan libraries for cancer glycobiology, focusing on glycosphingolipids.
SGS to Offer HDX–MS at West Chester Facility
SGS has announced that it will expand its higher order structure analysis services for proteins at its West Chester, PA facility with an investment in Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) capabilities.

Events
Mass Spec 2016 - 13th Symposiu
27 Sep 2016
Mass Spec 2016 - 13th Symposiu ...
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Featured Event - 3rd International conference o
10 Oct 2016
3rd International conference o ...
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A Streamline Approach for Biot
12 Oct 2016
A Streamline Approach for Biot ...
More information
WWEM - Water, Wastewater & Env
02 Nov 2016
WWEM - Water, Wastewater & Env ...
More information

ePosters
Development and Application of Quantitative Immunoassays for Major Milk Allergens Bos d 5 (β-lactoglobulin) and Bos d 11 (β-casein)
1. Indoor Biotechnologies, Ltd., Cardiff, Wales, UK. 2. INRA, Gif-sur-Yvette, France

In this study, we sought to develop accurate, sensitive and reliable assays that would enable quantification of multiple milk allergens.
A Novel Benchtop Time-of-Flight GC-MS System for High Performance Analysis of Human Urine
LECO Corporation

A workflow was developed and implemented for the effective comparison of urine. It involved the preparation of stable compounds through derivatization, data acquisition using a high performance benchtop TOFMS, comprehensive data processing (NonTarget Deconvolution™), and quick retrospective analysis of rich datasets using Target Analyte Finding.

Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
Accurate Mass Spectral Database: Harnessing the Power of High Performance Mass Spectrometry at Long Last
LECO Corporation, Moscow State University

Standard mixtures comprising of alkanes, PAHs, semivolatiles, and pesticides were analyzed using a high resolution time-of-flight (HRTOF) mass spectrometer—Pegasus GC-HRT (LECO Corporation, Saint Joseph,MI)—at 10 spectra-per-second (m/z40–300) in high resolution mode (25,000 at FWHH). The resulting chromatographic peaks were automatically found, deconvoluted, and curated into an Accurate Mass Library (AML).
Automated Sample Preparation of Whole Blood for Therapeutic Drug Monitoring and Diagnostics by LC-MS using a Commercial Autosampler
1 University of Applied Sciences and Arts Northwestern Switzerland FHNW, Institute for Chemistry and Bioanalytics , Gründenstrasse 40, 4132 Muttenz; 2 CTC Analytics AG; Industriestrasse 20, CH-4222 Zw

In this poster the parameters necessary to automatically prepare whole blood samples for online LC-MS applications in the field of diagnostics and TDM have been investigated. A strategy and the most important parameters are shown for the optimization of a PAL RTC autosampler
for the preparation of whole blood samples.
Development and Application of Quantitative Immunoassays for Major Milk Allergens Bos d 5 (ß-lactoglobulin) and Bos d 11 (ß-casein)
1. Indoor Biotechnologies, Ltd., Cardiff, Wales, UK. 2. INRA, Gif-sur-Yvette, France

In this study, we sought to develop accurate, sensitive and reliable assays that would enable quantification of multiple milk allergens.

A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Instrumental Investigations: A Laboratory Manual of Forensic Analytical Chemistry
Oberlin College

A laboratory manual for undergraduate analytical and forensic chemistry courses
Determination of C2-C12 Aldehydes in Water by SPME Arrow On-Fiber Derivatization and GC/MS
1 BGB Analytik AG, Lettenstrasse 97, 8134 Adliswil, Switzerland; 2 CTC Analytics AG, Industriestrasse 20, 4222 Zwingen, Switzerland

A method applying SPME Arrow extraction and on-fiber derivatization for the quantitation of C2-C12 aldehydes in water by GC/MS is described.
Assessing Diversity in Cassava through the Application of Metabolomics
aSchool of Biological Sciences, Royal Holloway University of London, Egham, UK bInternational Center for Tropical Agriculture, CIAT

In the present study metabolomic platforms have been established for Cassava and used to assess the biodiversity present in Cassava germplasm collections and elucidate underlying biochemical mechanisms associated with traits of interest.
Application Notes
Integrating Automation and DOE to Streamline and Accelerate Quality by Design Activities for Process Chemistry
Unchained Labs

Unchained Labs' tools translate complex experiments into executable methods.
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research
SCIEX

The Lipidyzer™ Platform, powered by Metabolon®.
Novel Chemical Standards Kits Enable Facile Lipid Quantitation
SCIEX

The Lipidyzer platform provides more accurate lipid analysis with less quantitative bias.
Automated Sample Preparation - Analysis of 25-OH-Vitamin D3 and 25-OH-Vitamin D2 by LC/MS/MS
Beckman Coulter Life Sciences


Automated Sample Preparation for the Monitoring of Pharmaceutical and Illicit Drugs by LC-MS/MS
Beckman Coulter Life Sciences


Automated Sample Preparation for the Monitoring of Ethanol Metabolites in Urine by LC-MS/MS
Beckman Coulter Life Sciences


Automating Protein Digestion for Reproducible Proteomics
Beckman Coulter Life Sciences


Simple sample preparation for the determination of vitamin D in serum by LC-MSMS
Tecan Group Ltd.

A growing number of laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) for the determination of vitamin D. The advantage of the latter method is unparalleled specificity combined with high sensitivity, offering the potential for the determination of multiple analytes, such as 25OH-vitamin D3 and 25OH-vitamin D2.
Automated Sample Preparation of 25-OH-Vitamin D3/D2 from Serum with the AC Extraction Plate and the Tecan Freedom EVO® for the quantification by LC-MS/MS
Tecan Group Ltd.

There is an increasing demand for the determination of Vitamin D status which is based on the quantification of the two metabolites 25-OH-Vitamin D3/D2. Numerous laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) because of its specificity combined with high sensitivity. Moreover LC-MS/MS offers the potential for multianalyte determination which is required for Vitamin D status determination.
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
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