Corporate Banner
Satellite Banner
Mass Spectrometry
Scientific Community
Become a Member | Sign in
Home>News>This Article

Bruker and UMCG Announce a Collaboration within New ENRIA

Published: Monday, April 09, 2012
Last Updated: Monday, April 09, 2012
Bookmark and Share
Collaboration for MALDI-TOF mass spectrometry-based microbial identification.

At the 22nd ECCMID (European Congress of Clinical Microbiology and Infectious Diseases) in London, Bruker has announced a collaboration with UMCG within the new European Network for the Rapid Identification of Anaerobes (ENRIA), based on Bruker´s MALDI Biotyper system for MALDI-TOF mass spectrometry-based microbial identification.

Anaerobic infections belong to the neglected infectious diseases and are often underestimated in their importance.

However, anaerobic bacteria are important pathogens, composing also the majority of normal, probiotic bacterial flora on the mucosal surfaces and other bacterial ecologic systems in humans, animals and the environment.

Furthermore, anaerobes are key in the growing biofermentor-based renewable energy industry. Knowledge is still lacking on the importance of anaerobes as human pathogens in many infection processes, and their role of being a possible reservoir for virulence and resistance genes.

Therefore, a rapid and correct species identification of anaerobes is an indispensable prerequisite for future microbial diagnostics.

Classic identification of anaerobes has remained cumbersome and difficult to standardize over recent decades. Thus, anaerobic bacteria remain often unidentified in clinical microbiological practice.

The MALDI Biotyper has recently opened the possibility to use MALDI-TOF mass spectrometry for the rapid identification of anaerobic bacteria.

In collaboration with the ESCMID Study Group of Anaerobic Infections (ESGAI), UMCG and Bruker, the new European Network for Rapid Identification of Anaerobes (ENRIA) has now been initiated (

It is coordinated by the Dutch expert center for anaerobic bacteria at the Department of Medical Microbiology of the University Medical Center Groningen (UMCG) in the Netherlands and the Hungarian Reference Laboratory for Anaerobic Infections at the University of Szeged in Hungary.

Since many years, both expert centers are leading in culture-based and molecular analysis of anaerobes, including oral and gut microbiology.

ENRIA will set up an international and well-characterized anaerobic strain collection comprising of the most important anaerobic species, including parodontogenic bacteria.

Reference spectra of this strain collection will be added to Bruker´s MALDI Biotyper database. ENRIA will offer international workshops for standardization of MALDI-TOF MS usage in the identification of anaerobic bacteria.

Finally, participating laboratories will perform a quality certification for the rapid identification of anaerobic bacteria with excellent quality using classical detection methods and MALDI-TOF MS.

The initiators and ENRIA project lead partners are Prof. Alex W. Friedrich (Chair of Medical Microbiology and Head of the Department of Medical Microbiology of the University of Groningen), Prof. Elisabeth Nagy (Chair of the ESGAI group) and Dr. Wolfgang Pusch (Executive Vice President at Bruker Daltonics).

Prof. Dr. Elisabeth Nagy, Institute of Clinical Microbiology, University of Szeged, Hungary and Chair of the ESGAI commented: "With the ENRIA project I envision the chance of a European-wide revival of rapid identification of anaerobic infections, combined with excellence in detection quality. This builds finally the basis for correct microbiological diagnostics, appropriate clinical management and further basic and applied research in the field of anaerobic infections."

Prof. Dr. Alex Friedrich, Chair of Medical Microbiology and Infection Control, University Medical Center Groningen, further stated: "The MALDI Biotyper method of using proteomic fingerprints for MALDI-TOF mass spectrometry-based microbial identification is of special interest for anaerobic bacteria, as they are typically slow growing and inactive in biochemical tests. Moreover, the MALDI Biotyper is using a molecular fingerprint and is not dependent on certain metabolic properties of the respective bacteria. This allows for a much more unambiguous identification of this difficult group of bacteria and opens new perspectives for rapid identification and biotyping. The ENRIA initiative aims towards further building up such identification capabilities by including additional anaerobic isolates from other major European expert laboratories in this field. The UMC Groningen will organize subsequent proficiency tests to establish this approach as the standard for anaerobic bacteria identification."

Dr. Wolfgang Pusch, Executive Vice President, Microbiology Business at Bruker Daltonics concluded: "In the last years the MALDI Biotyper has been widely accepted as the de facto standard for microbial identification. The cooperation with UMCG and the ENRIA project will further establish the system also for anaerobic bacteria in the fields of clinical microbiology, veterinary microbiology as well as for applications in environmental and industrial microbiology."

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

PREMIER Biosoft Announces Reseller Agreement with Bruker
Agreement aims to advance lipidomics and metabolomics research.
Monday, November 17, 2014
Bruker Sells GC Business
Bruker completed the divestiture of its GC and GC single-quadrupole (GC-SQ) mass spectrometry products to Techcomp Europe Ltd on October 31st.
Tuesday, November 04, 2014
Using LC-MS to Analyse Sulfonamides in Food Grade Honey
Sulfonamides are one of a number of groups of chemicals whose presence in honey is limited by international regulations.
Tuesday, July 22, 2014
Bruker MALDI Biotyper™ Receives CFDA Clearance
Company receives clearance from the China Food and Drug Administration to market and sell its IVD MALDI Biotyper System as a medical device in China for the identification of microorganisms isolated from human specimens.
Thursday, June 26, 2014
Bruker Reports 7% Revenue Growth in Q4
Bruker Corporation reported financial results for its fourth quarter and full year ended December 31, 2013.
Wednesday, February 19, 2014
Bruker Granted FDA Clearance to Market the MALDI Biotyper CA System
Bruker able to market MALDI Biotyper CA System in the US for the identification of Gram negative bacterial colonies cultured from human specimens.
Tuesday, November 26, 2013
Bruker and SISCAPA Assay Technologies Announce Second-Phase Collaboration Agreement
The ongoing collaboration aims to exploit MALDI-TOF instruments as an alternative to nano-LC-MS technology currently used in many SISCAPA assays.
Monday, September 16, 2013
Bruker and ImaBiotech Announces Collaboration
Bruker to distribute ImaBiotech's Quantinetix software for quantitative MALDI imaging.
Friday, June 21, 2013
Bruker and 3M Sign Exclusive Patent License Agreement
The licensed 3M patents are directed to a technique for performing mass spectrometry analysis on proteins in tissue that has been preserved in paraffin.
Tuesday, June 04, 2013
Bruker and SCiLS GmbH Announce an Exclusive Partnership
SCiLS Lab is the software developed by SCiLS GmbH which allows the user-friendly statistical analysis of large MALDI imaging datasets.
Wednesday, May 15, 2013
Biodesix Announces Agreement with Bruker Daltonics
The collaborative agreement sees Bruker Daltonics support Biodesix’ VeriStrat diagnostic test as well as future diagnostic tests based on MALDI-TOF mass spectrometry.
Wednesday, April 24, 2013
Bruker and the Genome British Columbia Proteomics Centre to Collaborate
The collaborative effort covers the development and validation of high-throughput assays for determining hemoglobin variants and diabetes risk.
Thursday, April 18, 2013
Bruker and Erasmus Medical Center Sign an Exclusive Licensing Agreement
Agreement for adding rapid beta-lactamase testing capabilities to the MALDI Biotyper system.
Friday, January 04, 2013
Bruker Announces New UK Centre of Excellence
Company introduces its integrated, state-of-the-art demonstration, applications and customer collaboration facilities.
Wednesday, October 03, 2012
Bruker and JMI Laboratories Announce Collaboration for Mass Spectrometry
The collaboration sees Bruker and JMI Laboratories partner in the field of fungal identification by proteomics fingerprinting.
Wednesday, June 20, 2012
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
New Method Identifies Up to Twice as Many Proteins and Peptides
An international team of researchers developed a method that identifies up to twice as many proteins and peptides in mass spectrometry data than conventional approaches.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
Acetaldehyde and Formaldehyde Content in Foods
Korean researchers have determined the content of the toxic and carcinogenic aldehydes, acetaldehyde and formaldehyde, in a variety of food groups.
Combining the Power of Mass Spectrometry & Microscopy
A tool that provides world-class microscopy and spatially resolved chemical analysis shows considerable promise for advancing a number of areas of study, including chemical science, pharmaceutical development and disease progression.
Increasing Vitamin D Supplementation
New study from ETH Zurich finds that elderly women should consume more vitamin D than previously recommended during the winter months.
Advancing Lithium-Ion Battery Research
The increasing number of components in a lithium-ion battery makes it essential to use a variety of analytical methods to attain complete characterization.
Clearest Ever Images of Enzyme that Plays Key Roles in Aging, Cancer
UCLA-led research on telomerase could lead to new strategies for treating disease
Fruit Fly Pheromone Flags Great Real Estate for Starting a Family
Finding could aid efforts to control mosquito-borne diseases like malaria by manipulating odorants
Education and Expense: The Barriers to Mass Spectrometry in Clinical Laboratories?
Here we examine the perceived barriers to mass spec in clinical laboratories and explore the possible drivers behind the recent shift in uptake of the technology in clinical settings.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos