Corporate Banner
Satellite Banner
Mass Spectrometry
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

AB SCIEX Launches Next-generation TripleTOF™ 5600 System

Published: Thursday, May 24, 2012
Last Updated: Thursday, May 24, 2012
Bookmark and Share
New system in TripleTOF™ family delivers advanced features, including SWATH™ Acquisition, SelexION™ compatibility and software that is capable of supporting 21 CFR Part 11 compliance.

AB SCIEX has announced the launch of the second generation of the TripleTOF™ 5600 System. The new TripleTOF™ 5600+ System delivers novel innovation for biomolecule research with MS/MSALL with SWATH™ Acquisition and supports a higher level of selectivity when coupled with SelexION™ Technology.

The new system also comes with software that is capable of supporting 21 CFR Part 11 compliance, making TripleTOF™ technology more accessible for regulated labs in the pharmaceutical industry.

The TripleTOF 5600+ is on display at this week’s American Society of Mass Spectrometry (ASMS) conference in Vancouver.

The new TripleTOF™ 5600+ system represents an advance in accurate mass technology that combines high resolution with sensitivity and speed.

This system builds on the proven innovation of the original TripleTOF™ 5600, which was launched at ASMS in 2010, and is now the industry’s fastest, high sensitivity, high-resolution mass spectrometer for simultaneous high-performance qualitative and quantitative analysis.

A built-in capability to support SelexION™ Technology further adds versatility and breakthrough levels of selectivity.

SWATH™ Acquisition is a mass spectrometry-based technique that quantifies nearly all peptides and proteins in a sample from a single analysis.

By incorporating support for MS/MSALL with SWATH™ Acquisition on the TripleTOF™ 5600+ platform, researchers will be able to obtain more information about proteins, peptides and other biomolecules from a sample than ever before.

The TripleTOF™ 5600+ is the only platform in the industry that has the speed, sensitivity and dynamic range to enable SWATH™ Acquisition, which was developed through collaboration with leading proteomics researcher Ruedi Aebersold, Ph.D., based at ETH Zurich, and has already received positive feedback from the scientific community.

“The combination of the AB SCIEX TripleTOF™ 5600+ system and the recent development of SWATH acquisition has completely changed how I think about designing and implementing quantitative proteomics studies,” said Bradford W. Gibson, Ph.D., Professor & Director of Chemistry and Mass Spectrometry, Buck Institute for Research on Aging.

Gibson continued, “The high resolution and fast scanning capabilities of the TripleTOF have made it possible for the first time to acquire MS and MS/MS ion intensity data on essentially all peptides in a single run that can be mined both immediately and retrospectively. This is truly a revolutionary combination of instrumentation technologies and software innovation.”

AB SCIEX is extending the utility of TripleTOF™ technology for use in pharmaceutical laboratories, addressing a need for compliance to 21 CFR Part 11 for electronic records and signatures.

With software capable of supporting 21 CFR Part 11 compliance, the new TripleTOF solution opens up new possibilities for drug discovery labs to meet this regulatory requirement.

“The launch of the TripleTOF 5600+ System is exactly two years after the first TripleTOF instrument broke new ground in the mass spectrometry industry and changed the way scientists approach analyses of drugs, contaminants and proteins,” said Dave Hicks, Vice President of the Pharma & Academic Business at AB SCIEX.

Hicks continued, “Now, we are continuing the evolution of the TripleTOF platform with new functionality that directly addresses feedback from customers who want to push the limits in their quantitative and qualitative analyses.”

Compatibility with SelexION™ Technology is another new feature of the TripleTOF™ 5600+ system, developed in response to customer feedback.

SelexION™ Technology delivers a new dimension of selectivity by adding differential ion mobility to conventional mass spectrometry for both quantitative and qualitative analysis.

It significantly improves selectivity and performance for any application requiring the separation of isobaric species, isolation of challenging co-eluting contaminants and elimination of high background noise. This advancement reduces sample preparation requirements and improves overall data quality.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

SCIEX Works with the Francis Crick Institute and the University of Cambridge
New proteomic study to develop advanced resource for precision medicine research by using Microflow SWATH® Acquisition for HT industrialized proteomics.
Wednesday, June 29, 2016
SCIEX, QPS Holdings Collaborate
Agreement aims to advance the hybrid LBA-LCMS workflow for biologics quantification.
Wednesday, April 06, 2016
SCIEX, Children's Medical Research Institute Collaborate
SCIEX industrialized proteomics solutions, using SWATH® Acquisition-based workflows and powered by the OneOmics™ Project, will enable large scale proteome studies to advance cancer research.
Thursday, February 11, 2016
SCIEX, A*STAR’s BTI Launch Collaboration
Agreement aims to boost innovation of protein drugs that target new diseases and are safer for patients.
Wednesday, January 27, 2016
SCIEX, Pressure BioSciences Partner
SCIEX and Pressure BioSciences to offer complete solution for next-generation proteomics, to increase the reproducibility and depth of proteomic analysis.
Wednesday, January 13, 2016
SCIEX, University of Manchester Partner
SWATH® Acquisition-based next-generation proteomics technology promises to make industrial proteomics a reality.
Thursday, October 29, 2015
SCIEX Partners with the Paulovich Lab at Fred Hutchinson Cancer Research Center
Collaboration targets research reproducibility crisis with highly validated multiplex quantitation assays.
Wednesday, September 23, 2015
SCIEX and New Objective Announce Partnership
New nanospray sources to offer maximum sensitivity and robustness for NanoLC-MS.
Tuesday, June 02, 2015
SCIEX and New Objective Partner
Partnership will provide advanced nanospray ionization technologies for next-generation proteomics.
Tuesday, May 26, 2015
SCIEX and Hepregen Announce Co-Marketing Agreement
Alliance establishes SCIEX and Hepregen as a one-stop solution provider for drug metabolism investigators.
Friday, May 22, 2015
SCIEX and Mass Consortium Corporation Announce Exclusive Reseller Agreement
SCIEX to provide customers with XCMSplus software solution for simplified and accelerated metabolomics workflows.
Tuesday, March 31, 2015
SCIEX and Labor Berlin Collaboration to Advance Forensic Testing
Collaboration for the development of a hybrid Quadrupole Time-of-Flight (TOF) MS/MS reference library.
Thursday, March 05, 2015
New Capabilities for Bioanalysis Studies at the International Pharmaceutical Research Center
AB SCIEX Triple Quad™ 6500 LC/MS/MS systems enable new levels of sensitivity for clinical trials of inhaled drugs.
Wednesday, February 11, 2015
Improved Accuracy of Pesticide Detection in Food
European Reference Laboratory improves accuracy of pesticide detection in food with AB SCIEX mass spectrometry instrumentation.
Wednesday, February 04, 2015
AB SCIEX Wins New Product Innovation Award in Asia Pacific
The award recognizes the company’s continued innovation in the mass spectrometry industry and a number of new products introduced into the market in recent years.
Thursday, October 30, 2014
Scientific News
JPK NanoWizard® Applied to a Wide Range of Research
The NanoWizard® AFM from JPK is applied for interdisciplinary research at the University of South Australia for applications including smart wound healing and how plants can protect themselves from toxins.
New Centre Offers Ultra-Speed Protein Analysis
UW-Madison researchers to establish development centre for next-gen protein measurement technologies.
Determination of 13 Organic Toxicants in Human Blood
Researchers have utilised liquid-liquid extraction coupling HPLC-MS/MS to identify and quantify organic toxicants in human blood.
Accessing Metabolic Information with Mass Spec
Scientists at the Helmholtz Zentrum München have developed a new mass spectrometry imaging method which, for the first time, makes it possible to analyze hundreds of metabolites in fixed tissue samples.
Unravelling the Roots of Insect’s Waterproof Coating
Researchers have identified the genes that control cuticular lipid production in Drosophila, by performing an RNAi screen and using Direct Analysis in Real Time and GC-MS.
Massive Helium Discovery a "Game Changer" for Medical Industry
A new development is gas exploration has yielded the discovery of a huge helium gas field, which could help relieve the dwindling supply.
Unidentified Spectra Detector
New algorithm clusters over 250 million spectra for analysis, such that millions of unidentified peptide sequences can be recognised.
Making Metabolite Identification More Efficient
Metasense combines the industry's most-comprehensive metabolic transformation prediction with efficient analysis of LC/MS analytical measurements to identify, visualize, and report chemical biotransformations.
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Scroll Up
Scroll Down
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!