Corporate Banner
Satellite Banner
Mass Spectrometry
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

ChromaDex® and Scripps Research Institute Collaborate on METLIN Metabolite Database

Published: Friday, June 01, 2012
Last Updated: Friday, June 01, 2012
Bookmark and Share
The collaboration with The Scripps Center for Metabolomics will generate tandem mass spectrometry data for compounds from the ChromaDex natural products and phytochemical catalog.

The Scripps METLIN Metabolite Database is a repository of metabolite information that includes tandem mass spectrometry data for over 55,000 unique and potentially therapeutic compounds. It is a public, web-based database designed for the archiving, visualization, and analysis of metabolite data. The information is provided to facilitate metabolomics experiments by providing scientists with a comprehensive source of structures for potential metabolites of their compounds of interest. An annotated list of known metabolites and their mass, chemical formula, and structure are available on the METLIN website. The METLIN database was developed and is maintained by the Siuzdak laboratory at the Scripps Research Institute, La Jolla, California.

Currently, there is limited information for natural products in the database. By expanding the population of data, it will increase the knowledge base and visibility for researchers to screen potential compounds for use in areas of clinical interest, such as cancer, heart disease, diabetes, or Alzheimer's.

"We are very excited about expanding the METLIN metabolite database with the ChromaDex phytochemicals.  METLIN is currently the largest repository of metabolite tandem mass spectrometry data.  This important class of ChromaDex compounds will expand METLIN's compound library and mass spectrometry data to nutraceuticals and many novel plant-related natural products.   The importance in the ChromaDex/METLIN partnership is that it will facilitate metabolomics experiments around the world." states Gary Siuzdak Ph.D, Senior Director, Center for Metabolomics and Mass Spectrometry Scripps Research Institute.

Frank Jaksch, Founder and CSO for ChromaDex, stated "Collaborating with Scripps Research Institute with our natural product libraries will further advance small molecule profiling to increase demand for natural product libraries through the ease of the Internet to assist in finding candidate compounds for research and development."


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
New ACE-inhibiting Molecule Found in the Asparagus
Scientists have determined that sulfur-containing compounds in plants can inhibit ACE.
The Linking of Molecules and Microbes
Researchers have succeeded in making antibiotic substances and their bacterial producers simultaneously visible.
PTR-MS Breath Test Shows Potential for Detecting Liver Disease
Researchers at the University of Birmingham have published results that suggest a non-invasive breath test for liver disease using an IONICON PTR-MS.
New Test Could Distinguish Between Bipolar Disorder, Depression
Scientists are developing a test that could tell the difference between bipolar disorder and depression.
Early Detection of Lung Cancer
The University of Manchester has signed a collaboration agreement with Abcodia to perform proteomics studies on a cohort of non-small cell lung cancer cases from the UKCTOCS biobank, with the aim of discovering new blood-based biomarkers for earlier detection of the disease.
Detecting Hidden Ingredients
Researchers from China have used mass spectrometry to reveal the use of undeclared substances in dietary supplements.
How the Lung Repairs its Wounds
Researchers have gained detailed insights into the dynamic remodeling of the tissue during lung repair.
Automation Abound at AACC in Atlanta
Discover the latest breakthroughs, trends and products from the AACC Annual Meeting & Clinical Lab Expo.
Could a simple saliva test detect Alzheimer's?
Researchers have presented findings suggesting that a simple, non-invasive diagnostic for Alzheimer's could be within reach.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!