Corporate Banner
Satellite Banner
Mass Spectrometry
Scientific Community
Become a Member | Sign in
Home>News>This Article

A LoGiCal® Success for Online SPE-LC/MSMS

Published: Thursday, November 29, 2012
Last Updated: Thursday, November 29, 2012
Bookmark and Share
Online SPE-LC/MSMS method for the analysis of synthetic cannabinoids.

LoGiCal® reference materials from LGC Standards have enabled specialist instrument manufacturer Spark Holland in Emmen, the Netherlands, to establish an online SPE-LC/MSMS method for the analysis of synthetic cannabinoids.

Business Development Manager Martin Sibum explained: “We develop applications for a variety of markets, including clinical pharma, toxicology and forensics, and are involved in screening for drugs of abuse. The use of designer drugs is on the increase, and we needed to develop a quantitative online SPE-LC/MSMS method for the analysis of synthetic cannabinoids, or ‘Spice’ compounds. These compounds are relatively new, and LGC Standards was quite unique in being able to supply reference standards for five Spice compounds from stock.”

“Availability of these reference materials allowed us to quickly and easily prepare calibration standards for each compound, and to develop an automated SPE method on a Symbiosis™ system. Within two days, we had established an online SPE-LC/MSMS method for the quantification of five Spice compounds in urine. This was the first time we had worked with LGC Standards, and we achieved excellent results using LoGiCal reference materials. CVs were less than 5 % - and accuracy within ±10 % - for all compounds and concentrations, with correlation coefficients greater than 0.99. LGC Standards was really helpful and showed an interested in the results, so it was an excellent first collaboration.”

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,100+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
Could 2D Mass Spec Breakthrough Lead to Medical Revolution?
Pharmaceutical research could be quicker and more precise, thanks to an innovative breakthrough in 2D mass spec from the University of Warwick.
New Pathway for COPD Biomarker Development
A study from Philip Morris International has highlighted multi-lipid profiling as a potential new pathway for COPD biomarker development.
Reclaim from the Drain - The Importance of Water Reuse
This infographic explains the importance of reusing water to meet the world's increasing water demand.
Clinical Trial Finds Medicine Program Alters Blood Serum
Meditation, yoga and vegetarian diet linked to decline in plasma metabolites associated with inflammation and cardiovascular disease risk.
3D-Printing in Science: Conference Co-Staged with LABVOLUTION
LABVOLUTION 2017 will have an added highlight of a simultaneous conference, "3D-Printing in Science".
Antibiotic Resistance Can Occur Naturally in Soil Bacteria
Scientists have found natural anti-biotic resistant bacteria in soils with little to no human exposure.
Gene Deletion Reveals Cell Secrets
Researchers have deleted 174 genes in yeast to analyse the effect of individual gene deletion.
Peer Reviewed Study Demonstrates Mass Spec Technique
The peer reviewed study demonstrates MS workflow, TMTCalibrator workflow, which dramatically enhances detection of key early stage Alzheimer’s biomarkers.
Impact of Emerging Contaminants in Our Water Supply
Emerging contaminants, any synthetic or naturally occurring chemical not commonly monitored in the environment, in our water supply are becoming of increasing concern due to their potential ecological and/or human health effects.
Scroll Up
Scroll Down

SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,100+ scientific videos