Corporate Banner
Satellite Banner
Mass Spectrometry
Scientific Community
Become a Member | Sign in
Home>News>This Article

PREMIER Biosoft Releases SimGlycan v. 5.0

Published: Friday, June 13, 2014
Last Updated: Thursday, June 12, 2014
Bookmark and Share
PREMIER Biosoft has announced the release of SimGlycan v. 5.0 to provide informatics support to Thermo Scientific LC-mass spectrometry (MS) methods.

PREMIER Biosoft, a next generation leader in bioinformatics, has announced the release of a new version of SimGlycan®, a comprehensive, high throughput tool to provide automated informatics support for LC-MS and MS/MS glycan data analysis workflows. The new version of the software facilitates processing of LC-MS and MS/MS data for peak detection, peak picking and alignment of glycans based on retention time, precursor m/z values, observed intensities across multiple samples.

According to Julian Saba, Senior Scientist at Thermo Scientific™, "Recent developments in mixed–mode column chemistries and faster scanning mass spectrometers have increased the number of glycans resolved and identified by LC-MS workflows thereby delivering an unmatched analytical solution for glycan research. Our sophisticated workflows, along with SimGlycan® as the informatics support,  provide best-in-class glycan analysis. "

The newly developed glycomics workflow that features Thermo Scientific™ GlycanPac™ AXR-1 column coupled to a Thermo Scientific™ Orbitrap™ Fusion™ Tribrid mass spectrometer or Thermo ScientificTM Q ExactiveTM hybrid quadrupole-Orbitrap mass spectrometer enable resolution and identification of far more structures compared to other commercially available column technologies. However, the increase in peak resolution and detected compounds lead to large data sets. Manual deconvolution of complex chromatograms, identification of isotopic peaks, identifying MS/MS scans for detected compounds and selection of correct precursor m/z values from the isotope cluster for MS/MS data analysis is effectively incorporated in SimGlycan®.

"As instruments get more sophisticated and aim to deliver highly accurate results, our effort is to upgrade the informatics support in the hands of the glycomics community to precisely interpret the new data analysis workflows supported by Thermo's instruments." said Arun Apte, CEO at PREMIER Biosoft.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Dr. Vladimir Shulaev Joins PREMIER Biosoft Scientific Advisory Board
Dr. Shulaev joins SAB to further the development of software solutions for metabolomics and lipidomics research.
Saturday, September 19, 2015
PREMIER Biosoft Announces Collaboration with University of Utah
Formal collaboration to advance metabolomics and lipidomics research.
Friday, August 07, 2015
PREMIER Biosoft and JEOL Enter Agreement
The co-marketing agreement aims to advance research involving marker studies, drug metabolite profiling, lipid and proteomics analysis using MALDI-IMS technology.
Thursday, June 06, 2013
PREMIER Biosoft Acquires ProteoIQ
Company adds strength to its mass spectrometry product portfolio with the acquisition of ProteoIQ from NuSep, Australia.
Tuesday, March 12, 2013
Scientific News
Newly Identified Biochemical Pathway Could Be Target for Insulin Control
Researchers at Duke Medicine and the University of Alberta are reporting the identification of a new biochemical pathway to control insulin secretion from islet beta cells in the pancreas, establishing a potential target for insulin control.
Dirty,Crusty Meals Fit for (Long-Dormant) Microbes
Researchers apply the latest analytical techniques to further our understanding of desert biocrusts.
CSI -- On The Metabolite's Trail
Bioinformaticians at the University of Jena make the most efficient search engine for molecular structures available online.
First Complete Structural Study Of A Pegylated Protein
Significant data obtained at NUI Galway reports first crystal structure of a protein modified with a single PEG chain.
Potential Ovarian Cancer Biomarker Isolated
Researchers from North Carolina State University utilized a highly sensitive mass spectrometry analysis to identify and measure difficult-to-detect N-glycan biomarkers associated with ovarian cancers in stages I – IV.
Waters’ Centers of Innovation Program Honors Ohio State University Laboratory
Wysocki-led facility recognized for proteomics, disease research and mass spectrometry excellence.
Protein Aggregation After Heat Shock Is An Organized, Reversible Response
New study finds protein aggregation after heat exposure is a reversible cellular process, not unrecoverable damage from misfolding.
World’s Largest Protein Interaction Map Created
A multinational team of scientists sifted through cells of vastly different organisms – from amoebae to worms to mice to humans – to reveal how proteins fit together to build different cells and bodies.
Evidence of Ancient Life Discovered Deep Below the Seafloor
Ancient rocks harbored microbial life deep below the seafloor, reports a team of scientists from the Woods Hole Oceanographic Institution (WHOI), Virginia Tech, and the University of Bremen.
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos