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Using a Spike-in Experiment to Evaluate Analysis of LC-MS Data
Data from the spike-in experiment can be used for developing and optimizing LC-MS data preprocessing algorithms and to evaluate workflows implemented in existing software tools. LC-Tandem MS Analysis of Perfluorooctane Sulfonate and Perfluorooctanoic Acid in Fish Fillets The methodology, developed by researchers from Mario Negri Institute, can be used to monitor and assess human exposure to perfluorinated compounds through sea food consumption. Lipidomics of Intact Mitochondria by MALDI-TOF/MS Researchers from University of Bari Aldo Moro describe a simple and fast method of lipid analyses of isolated intact mitochondria by means of MALDI-TOF mass spectrometry. Characterisation of Flavonoid Aglycones by Negative Ion Chip-Based Nanospray Tandem Mass Spectrometry Researchers from the University of Bristol employ this technique for the identification of medium-polarity flavonoids from a simple extract of green tea without employing any prior sample preparation, cleanup or chromatography. Warwick Researchers Solve 40-year-old Fourier Transform Mass Spectrometry Phasing Problem Scientists at the University of Warwick have developed a computation which simultaneously doubles the resolution, sensitivity and mass accuracy of Fourier Transform Mass Spectrometry at no extra cost. Proteomics: Top European Researcher Scoops two Prestigious Science Awards A German researcher has just been awarded not one but two top science accolades for his research in mass spectrometry. Breakthrough Proteomics Technique SWATH™ Acquisition is Made Available to the Worldwide Scientific Community Data-independent SWATH™ Acquisition on the TripleTOF™ 5600 system enables comprehensive proteome-wide quantitation and is published in Molecular and Cellular Proteomics. Proteomic Profiling and Protein Identification by MALDI-TOF Mass Spectrometry in Unsequenced Parasitic Nematodes Researchers from the University of Liverpool utilise MALDI-TOF MS in conjunction with Peptide Mass Fingerprint searching for the reliable protein identification in unsequenced organisms. Development of a Screening Method for the Determination of PCBs in Water This novel method utilises gas chromatography coupled to triple quadrupole mass spectrometry for the simultaneous analysis of 11 polychlorinated biphenyls. Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and Analysis This paper provides an overview of the data processing tools available, offering a review of the collection of recent reports on the topic. 
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