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Investigating the Effects of Commercial Antimicrobial Agents on Human Corneal Epithelial Cell Membranes
Ian J. Horner, Jerod J. Hurst, Nadine D. Kraut, Alyssa A. Rook, Crystal M. Collado, G Ekin-Atilla Gokcumen, and Frank V. Bright

Several commercial multi-purpose solutions (MPS) products contain polyhexamethylene biguanide (PHMB) and/or polyquaternium-1 (PQ-1) as antimicrobial agents. In this poster we report the effects of PHMB and PQ-1 on small unilamellar vesicles (SUV) that we have designed to mimic the average human corneal epithelial cell membrane.

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Aptamer-Based Electrochemical Biosensing Platform for Detection of Hormonal Pollutants in Water
Contreras Jimenez, G.; Eissa, S.; Ng, A.; Zourob, M.; Siaj, M.

A novel detection mechanism based on aptamers has been developed to detect small molecules as hormones, antibiotics, toxins, drugs, etc. For first time, an aptasensor to detect progesterone has been developed.

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An investigation into the effects of aging on automotive bumper samples by xylene soluble flow injection polymer analysis (XS-FIPA)
Bassem Sabagh, Wei Sen Wong, Bernd Tartsch

This poster describes the use of flow injection polymer analysis (FIPA) as an analytical tool for xylene soluble (XS) determination with quick and easy simultaneous measurements of molecular weight (MW), intrinsic viscosity (IV) and XS%. The technique was applied to automotive bumper samples which had undergone an aging test. The results from the XS-FIPA technique highlight the differences caused by the aging process.

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The role of AHPCO Technology in reducing allergic rhinitis cases as Air Purifier, Surface Sterilizer and Ice Maker sterilizer
Dr. Nabarun K. Ghosh, PhD1, Dr. Constantine K. Saadeh, MD FAAAAI2, Dr. Jeff Bennert, PhD CTN3 and Ms. Griselda Estrada, BS1

Dirty ice makers can cause potential health hazards. To prevent any potential contamination, the interior surfaces of the ice machine must be cleaned and sanitized regularly. This report justifies the demand and use of novel equipment that will sanitize the surface of an ice machine continuously. We evaluated the Bi-Polar® unit built by Air Oasis (1.2) in sanitizing the ice machine surface.

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Tolerance to Allergenic Foods Following Food Oral Immunotherapy (FOIT)
AR Hague1, RL Wasserman1,2, SK Silvers1,2, RW Sugerman1,2, M Herbert3

We report on 21 patients who completed FOIT (food oral immunotherapy) escalation followed by a period of maintenance dosing and later underwent a tolerance FC (food challenge). 90% of tested FOIT patients and 94% of patients who met our pre-defined criteria for tolerance FC achieved tolerance to their allergenic food.

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Single Practice Six-Year Experience Treating Food Allergy With Oral Immunotherapy
DM Pence1, AR Hague1, RL Wasserman1,2, SK Silvers1,2, RW Sugerman1,2, M Herbert3

We report a more-than-six-year experience with food oral immunotherapy (FOIT) in a private allergy practice setting. Most patients can be desensitized to one or more allergenic foods. Ongoing evaluation and modification of the FOIT procedures improves outcomes and acceptability. FOIT can be successfully performed in an allergy office.

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Ichthyophonus vs. Proteins: Should we be eating these fish?
Alisa Aist

The project, Ichthyophonus vs. Proteins, analyzes the effect of Ichthyophonus on the protein content of Halibut from Homer. This experiment found that Ichthyophonus does not have a significant effect on the protein content of the tested Halibut. The findings confirm the belief that Ichthyophonus is not harmful to humans and the Halibut are still safe to eat.

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Uncertainty estimation of an analytical method for analysis of fumonisin B1 in four types of rice intended for consumption human
Petrarca, M.H.; Rossi, E.A.; Sylos, C.M.

The expanded measurement uncertainty of a sample preparation method based on QuEChERS procedure for the determination of fumonisin B1 in four types of rice, using HPLC-FLD after precolumn derivatisation with ortho-phthaldialdehyde, was estimated from in-house validation data.

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B.M. Gurupadayya, S. Sharfuddin and R.S. Chandan

We developed LCMS/MS bioanalytical method for quantitative estimation of Pitofenone HCl in plasma is simple, sensitive, accurate, precise, and selective. Percentage recovery shows that the method is free from interference of matrix. The analytical method presented here has proved to be useful for investigation of the characteristics of Pitofenone in human plasma in pharmacokinetic and pharmacogenetic studies.

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Showing Results 11 - 20 of 146
Scientific News
Metabolomic Platform Reveals Fundamental Flaw in Common Lab Technology
A new study led by scientists at The Scripps Research Institute (TSRI) shows that a technology used in thousands of laboratories, called gas chromatography mass spectrometry (GC-MS), fundamentally alters the samples it analyzes.
New Hope for Personalized Treatment of Eczema
Pharmaceutical researchers at Oregon State University have developed a new approach to treat eczema and other inflammatory skin disorders that would use individual tests and advanced science to create personalized treatments based on each person's lipid deficiencies.
Flowing Electrons Help Ocean Microbes Gulp Methane
Recent work at Caltech has shown that microbes work together to consume large amounts of methane released from vents on the ocean floor by using electrons to share energy over long distances.
Thousands of Protein Interactions Identified
Thanks to the work by Utrecht University researcher Fan Liu and her colleagues, it is now possible to map the interactions between proteins in human cells.
Newly Identified Biochemical Pathway Could Be Target for Insulin Control
Researchers at Duke Medicine and the University of Alberta are reporting the identification of a new biochemical pathway to control insulin secretion from islet beta cells in the pancreas, establishing a potential target for insulin control.
Dirty,Crusty Meals Fit for (Long-Dormant) Microbes
Researchers apply the latest analytical techniques to further our understanding of desert biocrusts.
CSI -- On The Metabolite's Trail
Bioinformaticians at the University of Jena make the most efficient search engine for molecular structures available online.
First Complete Structural Study Of A Pegylated Protein
Significant data obtained at NUI Galway reports first crystal structure of a protein modified with a single PEG chain.
Potential Ovarian Cancer Biomarker Isolated
Researchers from North Carolina State University utilized a highly sensitive mass spectrometry analysis to identify and measure difficult-to-detect N-glycan biomarkers associated with ovarian cancers in stages I – IV.
Waters’ Centers of Innovation Program Honors Ohio State University Laboratory
Wysocki-led facility recognized for proteomics, disease research and mass spectrometry excellence.
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