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Increasing Extraction Efficiency of Pesticides and Dioxins from Wet Samples Using a Novel Polymer During Accelerated Solvent Extraction
Katerina Bousova, Pranathi Perati, Rahmat Ullah, Kannan Srinivasan

Thermo Scientific™ Dionex™ ASE™ Prep MAP is a proprietary polymer designed to remove moisture and increase extraction efficiencies from wet samples including soils, tissues and food products. This unique formulation allows moisture removal under a variety of ionic strength conditions and accelerated solvent extraction conditions.

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Identifying Unknown Chemicals and Disinfection Byproducts in Swimming Pools and Hot Tubs
Jonathan D. Byer, Susan D. Richardson, Eric J. Daiber, Sridevi Anduri Chowdary, Joe Binkley, Jeff Patrick

DBPs were identified in finished water, tap water, swimming pool water, and hot tub water that were not present in the source water. High Resolution Deconvolution was used effectively to identify a greater number of peaks in the chromatogram than by nominal resolution MS.

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Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
Ningombam Sanjib Meitei*(1); Arun Apte(2); Dietmar Waidelich(3); Fadi Abdi(4); Matthias Glueckmann(3)

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.

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Automatic Characterization of Lipids Using Charge Remote Fragmentation Ions and Peaks Characteristic of Fatty Acid Fragmentation From MALDI MS/MS Data
Ningombam Sanjib Meitei*(1); Arun Apte(2); Dietmar Waidelich(3); Fadi Abdi(4); Matthias Glueckmann(3)

Automated identification of lipids using CRF ions and high energy MS/MS fragment ions and novel software.

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Utilization of Hydrogen Carrier Gas on a High Resolution GC-TOFMS System: An Application Compendium
Joe Binkley, David Alonso

GC-HRT methods utilizing hydrogen carrier gas were developed for analysis of representative specialty chemical, forensic, and metabolomic markets.

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Integrated platform including automated bligh and dyer extraction and dual-column
Emmanuel Varesio, Guenter Boehm, Sandra Jahn, Renzo Picenoni, Gérard Hopfgartner

• Automated Bligh and Dyer extraction for metabolomic studies.
• Dual-column UHPLC setup for the analysis of the polar and lipidic fractions.
• Alternating acidic and basic mobile phase for the separation of the polar fraction.
• Identification of unknown compounds by SWATH HR MS2 spectra acquisition.

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Automated protein digestion workflows for MS-based proteomics applications
Gunnar Dittmar1, Oliver Popp1, Guenter Boehm2, Andreas Bruchmann3

The PAL RTC provides an affordable and reliable platform optimised for medium-throughput peptide preparation for shotgun-proteomics based mass spectrometry.
Reduce hands-on time on repetitive work!
Increase consistency!
Increase reproducibility

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Deciphering Regulatory Mechanisms in M. xanthus Using Isotopic Ratio Outlier Analysis (IROA) for Metabolome-wide Quantitation
Daniel Krug 1,2, Carsten Volz 1, Aiko Barsch 3, Chris Beecher 4, Felice de Jong 4, Rolf Müller 1,2

Comprehensive study of regulation in myxobacteria with an untargeted metabolomics setup using Isotopic Ratio Outlier Analysis (IROA) and UHR-Q-TOF

Reliable relative quantitation of known and unknown metabolites from a myxobacterial mutant strain in response to induction of the transcriptional antirepressor taA

Compound identification facilitated by the use of ultra-high resolution MS and the knowledge of the number of carbons in each molecule due to IROA

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Intact Protein LC-MS: How to Overcome the Challenges?
Robert van Ling, Evert-Jan Sneekes, Sebastiaan Dolman, Laurent Rieux, Mauro DePra, Christian Ravnsborg, Dafydd Milton, Remco Swart

Purpose: Facilitate intact protein LC-MS without compromising performance.
Methods: Construct prototypes of integrated column and sprayer dedicated for intact protein separations and compare performance.
Results: Three prototypes have been directly compared and all showed good protein separations, each with their unique area of strength.

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Scientific News
Scientists Come Up with New Technique to Detect Alien Life on Mars
Researchers have provided evidence that combining chromatography/mass spectroscopy with Raman spectroscopy could improve astrobiological studies.
New Test Detects Drug Use From A Single Fingerprint
Research published in the journal Analyst has demonstrated a new, non-invasive test that can detect cocaine use through a simple fingerprint.
Map Diagnostics Developing Mass Spec Test for Down Syndrome
The company hopes that this new test will provide an accessible, affordable and rapid alternative to current screening methods.
LECO Announces Special Events at ASMS
Company to host a series of events during the conference held at the America’s Center, Saint Louis, MO on May 31-June 4.
Discovery Accelerates Targeted Cancer Treatment
In collaboration with international scientists, researchers from the University of Copenhagen have developed a method to help shorten the road to better cancer treatment.
PNNL & Oregon Health & Science University Collaborate
Agreement pairs mass spectrometry and biomedical science expertise to open new doors for health.
ORNL Researchers Probe Chemistry, Topography and Mechanics with One Instrument
Scientists to explore thin films of phase-separated polymers.
Proteomics Identifies DNA Repair Toolbox
Max-Planck scientists identify protein profiles of DNA repair.
How an RNA Gene Silences a Whole Chromosome
Caltech study shows how Xist silences X-chromosomes.
Fake Malaria Drugs Not As Common As Previously Reported
Researchers welcome reassuring findings but note poor quality drugs are still a problem.
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